DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wrapper and Lsamp

DIOPT Version :9

Sequence 1:NP_477404.1 Gene:wrapper / 37555 FlyBaseID:FBgn0025878 Length:500 Species:Drosophila melanogaster
Sequence 2:XP_038944182.1 Gene:Lsamp / 29561 RGDID:71102 Length:378 Species:Rattus norvegicus


Alignment Length:320 Identity:88/320 - (27%)
Similarity:133/320 - (41%) Gaps:56/320 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly    25 LDFNNDLENSQKFKSIPTTVKTYENDTVQLPCTLNTPFRYVRW-HRDDVALVDSRHPELPPPDRI 88
            :|||...:|        .||:  :.||..|.|.:......|.| :|..:.........|.|  |:
  Rat    49 VDFNRGTDN--------ITVR--QGDTAILRCVVEDKNSKVAWLNRSGIIFAGHDKWSLDP--RV 101

  Fly    89 MLWPNG----SLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVLIEPSDLTEQRIGAI 149
            .|....    ||::..|...|.|.|.|.:.:.......|..:.||:.|::....||:|... |:.
  Rat   102 ELEKRHALEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVYLIVQVPPKISNISSDVTVNE-GSN 165

  Fly   150 FEVVCEAQGVPQPVITWRLNGNVIQPQSNTGNRQSLILEIK--SRNQAGLIECVASNGVGEPAVA 212
            ..:||.|.|.|:||||||    .:.|.......:...|||.  :|.|:|..||.|:|.|....|.
  Rat   166 VTLVCMANGRPEPVITWR----HLTPLGREFEGEEEYLEILGITREQSGKYECKAANEVSSADVK 226

  Fly   213 NVYLHVLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFH--------HGLPVALGAHST 269
            .|.:.|.:.|.::..:....| .|.:|.|:|...|.||...:|:.        :||.:    .||
  Rat   227 QVKVTVNYPPTITESKSNEAT-TGRQASLKCEASAVPAPDFEWYRDDTRINSANGLEI----KST 286

  Fly   270 THESELQ-TNRSVDHYVNAVRHMLVVKSVRNADMGQYECRASNQISVKSGSVELTGRPMP 328
            ..:|.|. ||.:.:||                  |.|.|.|:|::.|.:.|:.|..|.:|
  Rat   287 EGQSSLTVTNVTEEHY------------------GNYTCVAANKLGVTNASLVLFKRVLP 328

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wrapperNP_477404.1 Ig 41..124 CDD:299845 20/87 (23%)
IG_like 41..118 CDD:214653 20/81 (25%)
IG_like 145..218 CDD:214653 26/74 (35%)
Ig 147..219 CDD:299845 26/73 (36%)
I-set 224..323 CDD:254352 26/107 (24%)
IGc2 236..314 CDD:197706 23/86 (27%)
FN3 339..431 CDD:238020
LsampXP_038944182.1 Ig 55..145 CDD:416386 22/101 (22%)
FR1 55..71 CDD:409353 6/25 (24%)
Ig strand A' 56..62 CDD:409353 3/15 (20%)
Ig strand B 64..72 CDD:409353 4/7 (57%)
CDR1 72..76 CDD:409353 0/3 (0%)
FR2 77..84 CDD:409353 2/6 (33%)
Ig strand C 77..83 CDD:409353 2/5 (40%)
CDR2 85..95 CDD:409353 0/9 (0%)
Ig strand C' 87..90 CDD:409353 0/2 (0%)
Ig strand C' 92..95 CDD:409353 0/2 (0%)
FR3 96..131 CDD:409353 11/36 (31%)
Ig strand D 100..107 CDD:409353 2/6 (33%)
Ig strand E 110..116 CDD:409353 2/5 (40%)
Ig strand F 123..131 CDD:409353 3/7 (43%)
CDR3 132..136 CDD:409353 0/3 (0%)
Ig strand G 136..145 CDD:409353 1/8 (13%)
FR4 138..145 CDD:409353 1/6 (17%)
Ig_3 148..218 CDD:404760 26/74 (35%)
Ig strand A' 155..160 CDD:409353 2/4 (50%)
Ig strand B 166..173 CDD:409353 2/6 (33%)
Ig strand C 179..184 CDD:409353 5/8 (63%)
Ig strand D 190..193 CDD:409353 0/2 (0%)
Ig strand E 197..203 CDD:409353 3/5 (60%)
Ig strand F 210..217 CDD:409353 3/6 (50%)
Ig strand G 224..232 CDD:409353 2/7 (29%)
Ig_3 235..311 CDD:404760 24/98 (24%)
Ig strand B 252..256 CDD:409353 2/3 (67%)
Ig strand C 265..269 CDD:409353 0/3 (0%)
Ig strand E 290..294 CDD:409353 2/3 (67%)
Ig strand F 304..309 CDD:409353 2/4 (50%)
Ig strand G 318..321 CDD:409353 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.