DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wrapper and zig-3

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_509336.1	Gene:	zig-3 / 192088	WormBaseID:	WBGene00006980	Length:	251	Species:	Caenorhabditis elegans

Alignment Length:	256	Identity:	53/256 - (20%)
Similarity:	86/256 - (33%)	Gaps:	95/256 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 DSGHVVQQHAIEVQLAPQVLIEPSDLTEQRIGAIFEVVCEAQGVPQPVITWRLNGNVIQPQSNTG 180
            ||.|:..:.::::       ||..:......|....:.|:....|..||.|..:|..||     |
Worm    34 DSTHLTTKPSLKI-------IEGLEDNTVSTGESVTLRCDVLSTPTGVIYWEKDGQRIQ-----G 86

  Fly   181 NRQSLILEIKSRN------QAGLI-----------------ECVASNGVGEPAVANVYLH--VLF 220
            :::..:.| |..|      ::|:|                 :|||:||           |  |..
Worm    87 DKELNVFE-KVLNAMGPTVESGIITSSYQIPCANLHHIGSYKCVATNG-----------HDTVES 139

  Fly   221 SPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESELQTN------- 278
            |.::|:....|..|...|        :||..|:              ||....|||.|
Worm   140 SAKISVEGQTVKCKSTRR--------SAPVITM--------------STESRFELQDNAATLICR 182

  Fly   279 -------------RSVD----HYVNAVRHMLVVKSVRNADMGQYECRASNQISVKSGSVEL 322
                         :.:|    .|.......|:::.::.:|||.|.|.|.|:.....|...|
Worm   183 ADRRANWNWMFEDKKIDFDSGRYELLPSGDLLIRKIQWSDMGSYFCIAHNKYGESRGETFL 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	Ig	41..124	CDD:299845	3/7 (43%)
		IG_like	41..118	CDD:214653	1/1 (100%)
		IG_like	145..218	CDD:214653	21/97 (22%)
		Ig	147..219	CDD:299845	21/96 (22%)
		I-set	224..323	CDD:254352	25/123 (20%)
		IGc2	236..314	CDD:197706	20/101 (20%)
		FN3	339..431	CDD:238020
zig-3	NP_509336.1	I-set	45..145	CDD:254352	25/123 (20%)
		Ig	61..142	CDD:143165	22/97 (23%)
		IG_like	177..244	CDD:214653	12/67 (18%)
		Ig	<191..237	CDD:299845	10/45 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900