DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wrapper and zig-4

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_509335.1	Gene:	zig-4 / 181051	WormBaseID:	WBGene00006981	Length:	253	Species:	Caenorhabditis elegans

Alignment Length:	237	Identity:	51/237 - (21%)
Similarity:	79/237 - (33%)	Gaps:	71/237 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 QQHAIEVQLAPQV----LIEPSDL-----TEQRI---GAIFEVVCEAQGVPQPVITWRLNGNVIQ 174
            :.|:..|.||.::    |..|:.:     .|..:   |..:::.|:....|...|.|:.||.:||
Worm    23 EMHSAVVTLANEIDTNYLTSPAKIKIVAPLESALIPGGETYQLRCDIMSTPAATIHWKFNGKLIQ 87

  Fly   175 PQSNTGNRQSLI-----------------LEIKSRNQAGLIECVASNG------------VGEPA 210
            ..:.....:.|:                 ::..|...:|...||..||            .||.:
Worm    88 GSNELNVEEKLLNFGKAIVDTGIVASILTIQCPSAENSGTYSCVGYNGHQTIETVAEVEIEGEAS 152

  Fly   211 VANVYLHVLFSPEVSIPQPVVYT-----KLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTT 270
            ...       |...|.|:.|.:|     ..|:.|.|.|  .|.......|..:
Worm   153 GCR-------SNHKSAPEIVFWTDSRFEMTGNVATLVC--RANQQVDWVWMSN------------ 196

  Fly   271 HESELQTNRSVDHYVNAVRHMLVVKSVRNADMGQYECRASNQ 312
              .||..|.  |.:.......||:|::...|||.|.|.|.||
Worm   197 --DELVKNN--DKFTVLSNGDLVIKNIVWDDMGTYTCIARNQ 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	Ig	41..124	CDD:299845	0/1 (0%)
		IG_like	41..118	CDD:214653
		IG_like	145..218	CDD:214653	18/104 (17%)
		Ig	147..219	CDD:299845	18/100 (18%)
		I-set	224..323	CDD:254352	25/94 (27%)
		IGc2	236..314	CDD:197706	21/77 (27%)
		FN3	339..431	CDD:238020
zig-4	NP_509335.1	I-set	47..147	CDD:254352	17/99 (17%)
		Ig	65..144	CDD:143165	15/78 (19%)
		IG_like	176..245	CDD:214653	21/77 (27%)
		Ig	<193..238	CDD:299845	16/58 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900