DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wrapper and zig-8

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_499714.1	Gene:	zig-8 / 176732	WormBaseID:	WBGene00006985	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	187	Identity:	41/187 - (21%)
Similarity:	72/187 - (38%)	Gaps:	32/187 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 ENSQKFKSIPTTVKTYENDTVQLPCTLNTPFRY-VRWHR-DDVALVD------SRHPELPPPDR- 87
            |.|:......|.|.....:...|.|::.....: :.|.| .|.||:.      :|.|......:
Worm    33 ERSRVENPSQTIVNVVAENPAYLHCSVPPDAEHEIAWTRVSDGALLTAGNRTFTRDPRWQVSKKS 97

  Fly    88 IMLWPNGSLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVLIEPSDLTEQRIGAIF-- 150
            ..:|   .|.:...:..|:|.|.||:|.....|   :|:.:::....|..||.|.::....:.
Worm    98 ANIW---VLNLRRAEQQDSGCYLCEINDKHNTV---YAVYLKVLEPPLPSPSSLQKKSTKLMANM 156

  Fly   151 ---EVV--CEAQGVPQPV----ITWRLNGNVIQPQSNTGNRQSLILEIKSRNQAGLI 198
               |||  |......:..    :.|..:||.|    |..:.:..||::|  ..||::
Worm   157 SGDEVVLNCTVTSTDKDEEVLDVVWTRDGNTI----NFNDTEKYILKVK--RDAGVV 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	Ig	41..124	CDD:299845	20/91 (22%)
		IG_like	41..118	CDD:214653	19/85 (22%)
		IG_like	145..218	CDD:214653	14/65 (22%)
		Ig	147..219	CDD:299845	14/63 (22%)
		I-set	224..323	CDD:254352
		IGc2	236..314	CDD:197706
		FN3	339..431	CDD:238020
zig-8	NP_499714.1	IG_like	55..134	CDD:214653	19/84 (23%)
		Ig	55..129	CDD:143165	18/79 (23%)
		ig	158..229	CDD:278476	14/56 (25%)
		IG_like	158..227	CDD:214653	14/56 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900