DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wrapper and Fgfrl1

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	NP_473412.1	Gene:	Fgfrl1 / 116701	MGIID:	2150920	Length:	529	Species:	Mus musculus

Alignment Length:	273	Identity:	58/273 - (21%)
Similarity:	93/273 - (34%)	Gaps:	104/273 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 RIGAIFEVVCEAQGVPQPVITWRLNGNVIQ---------PQSNTGNRQSLILEIK--SRNQAGLI 198
            |:|....:.|..:|.|.|:..|..:|..|.         ||.         |::|  ....||:.
Mouse    38 RLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQG---------LKVKEVEAEDAGVY 93

  Fly   199 ECVASNGVGEPAVANVYLHVL--FSPEVSIPQP-----------------------------VVY 232
            .|.|:||.|..:| |..|.::  .||....|.|                             |:.
Mouse    94 VCKATNGFGSLSV-NYTLIIMDDISPGKESPGPGGSSGGQEDPASQQWARPRFTQPSKMRRRVIA 157

  Fly   233 TKLGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESELQTNRSVDHYVNAVRH-----ML 292
            ..:||...|:|:....|...:.|                   ::.::::.| :.|..|     .|
Mouse   158 RPVGSSVRLKCVASGHPRPDIMW-------------------MKDDQTLTH-LEASEHRKKKWTL 202

  Fly   293 VVKSVRNADMGQYECRASNQISVKSGSVELT--------GRPMPCLFKINP--------GT---- 337
            .:|:::..|.|:|.||.||    |:|::..|        .|..|.|...:|        ||
Mouse   203 SLKNLKPEDSGKYTCRVSN----KAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQ 263

  Fly   338 ---QSSTSHVLVW 347
               :|....|:.|
Mouse   264 CKVRSDVKPVIQW 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wrapper	NP_477404.1	Ig	41..124	CDD:299845
		IG_like	41..118	CDD:214653
		IG_like	145..218	CDD:214653	23/83 (28%)
		Ig	147..219	CDD:299845	22/82 (27%)
		I-set	224..323	CDD:254352	23/132 (17%)
		IGc2	236..314	CDD:197706	18/82 (22%)
		FN3	339..431	CDD:238020	3/9 (33%)
Fgfrl1	NP_473412.1	I-set	29..112	CDD:369462	23/83 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	116..151		4/34 (12%)
		Ig2_FGFRL1-like	153..234	CDD:143264	22/104 (21%)
		Ig	257..351	CDD:386229	5/20 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	405..427
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000