back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment wrapper and ncam1b

DIOPT Version :9

Sequence 1:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster
Sequence 2:	XP_005157462.1	Gene:	ncam1b / 114442	ZFINID:	ZDB-GENE-010822-2	Length:	1055	Species:	Danio rerio

Alignment Length:	496	Identity:	119/496 - (23%)
Similarity:	203/496 - (40%)	Gaps:	110/496 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GQVQA--ELDFNNDLENSQKFKSIPTTVKTYENDT---------VQLPCTLN-TPFRYVRWHRDD 71
            |:::|  |:||    .:.:...::..|::..:.:|         ..|.|..: .|...|.|.|::
Zfish   188 GRIKARGEVDF----RSIKVVVNVLPTIRIRQAETNATADMGFSTLLACDPDGFPEPIVTWRRNN 248

  Fly    72 VALVDSRHPELPPPDRIMLWPNGS-LQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEVQLAPQVL 135
            ..|...        ::.....:|| :.|.:|...|.|||.|...:.:|...|:.:::|.:.|::.
Zfish   249 APLESG--------NKYSFNEDGSEMTVLDVTKLDEGDYTCIAKNKAGESEQELSLKVFVQPKIT 305

  Fly   136 IEPSDLTEQRIGAIFEVVCEAQGVPQPVITWRLNGNVI-----------------QPQSNTG--- 180
            ...|..|.:....: .:.|||.|.|.|.|||.....|.                 :|:.:.|
Zfish   306 YLESQTTTEMDEQV-TLTCEATGDPTPTITWSFGTRVFTEGEQEQQKRIYQASWTRPEQHKGPDG 369

  Fly   181 --------NRQSLILEIKSRNQAGLIECVASNGVGEPAVANVYLHVLFSPEVSIPQPVVYTKLGS 237
                    ...||.|:......||...|.|.|.:|| .|..|.|.|.::|:: :....|||..|:
Zfish   370 EVLVRSDARVSSLTLKYPQYTDAGQYLCTARNAIGE-TVQPVSLEVRYAPKI-LGSVAVYTWEGN 432

  Fly   238 RAHLECIVEAAPA-ATVKWFHHG--LPVA----LGAHSTTHESELQTNRSVDHYVNAVRHMLVVK 295
            .|::.|.|.|.|: .::.|...|  ||.|    :..|:|...|.|:.|..
Zfish   433 PANISCEVLAHPSDVSITWLRDGFQLPNANTSNIKIHNTPSASYLEVNPE--------------- 482

  Fly   296 SVRNADMGQYECRASNQISVKSGSVELTGRPM---PCLFKINPGTQSSTSHVLVWQTESL--LPI 355
              ..:|.|.|.|..||:|..:|....:....:   |.:.::.|  .|||:.||..:.||.  :|:
Zfish   483 --SQSDFGNYNCTTSNEIGTESREFIMIPADVPSAPSIGEVQP--YSSTAQVLFEEPESTGGVPV 543

  Fly   356 MEFKLKFRQIPSNNVTRQVRTNWTELTIPAQATNGLIYITTYTLHGLQPASLYEVSVLARNSFGW 420
            ::::.::|.:.        |..|.:...  :..:||   ::.|:.||:|.:.|||.:.|.|..|.
Zfish   544 LKYRAEWRAVG--------RGKWVQRVY--EVKDGL---SSVTVTGLKPETDYEVKMSAINGKGE 595

  Fly   421 SDNSKIVRFATGGEVELPNYSTESELQDDFTEEDFHNEITQ 461
            .|:|..:.|.|    |...||..:.:      ..||.|.|:
Zfish   596 GDSSPSMVFKT----EHVRYSYTNGI------FHFHTEDTE 626

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.