DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wrapper and negr1

DIOPT Version :9

Sequence 1:NP_477404.1 Gene:wrapper / 37555 FlyBaseID:FBgn0025878 Length:500 Species:Drosophila melanogaster
Sequence 2:XP_031755650.1 Gene:negr1 / 100127726 XenbaseID:XB-GENE-987949 Length:388 Species:Xenopus tropicalis


Alignment Length:337 Identity:89/337 - (26%)
Similarity:139/337 - (41%) Gaps:48/337 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    11 CLL-AALILGQVQAELDFNNDLENSQKFKSIPTTVKTYENDTVQLPCTLNTPFRYVRW-HRDDVA 73
            ||| :.|..||   .:||        ::.::...| ..:.:|..|.|.|........| :|..:.
 Frog    27 CLLPSCLPAGQ---SMDF--------QWPAVDNLV-VRQGETAMLRCFLEEGASKGAWLNRSSII 79

  Fly    74 LVDSRHPELPPPDRIMLWPNG----SLQVANVQSSDTGDYYCEMNSD-SGHVVQQHAIEVQLAPQ 133
            ........:.|  |:.:..:.    ||::..|..||.|.|.|.:.:: |...:|.| :.|.::|:
 Frog    80 FAGGDKWSVDP--RVSIATSSKQEYSLRIQKVDVSDDGPYTCSVQTEHSPRTLQVH-LTVHVSPK 141

  Fly   134 VLIEPSDLTEQRIGAIFEVVCEAQGVPQPVITWRLNGNVIQPQSNT-GNRQSLILEIKSRNQAGL 197
            :....||:|... |....::|.|.|.|:|.|:||    .|.|.:.. |:.|.|.:...:|:|||.
 Frog   142 IYDISSDMTVNE-GTNVSLICLATGKPEPSISWR----HISPSAKQFGSGQYLDIYGITRDQAGD 201

  Fly   198 IECVASNGVGEPAVANVYLHVLFSPEVSIPQPVVYTKLGSRAHLECIVEAAPAATVKWFHHGLPV 262
            .||.|.|.|..|.|..|.:.|.|:|.:....| ....||....:.|...|.||...:|:.     
 Frog   202 YECSAENDVSFPDVKKVKVTVNFAPTILEITP-TGVSLGRTGLIRCETAAVPAPVFEWYK----- 260

  Fly   263 ALGAHSTTHESELQTNRSVDHYVNAVRHMLVVKSVRNADMGQYECRASNQISVKSGSVELTGRPM 327
              |....|:.   |....:.:|  ..|.:|.|.:|.....|.|.|.|.|::...:.|       :
 Frog   261 --GEKKLTNG---QRGIRIQNY--NTRSILTVSNVTEEHFGNYTCVAVNKLGTSNAS-------L 311

  Fly   328 PCLFKINPGTQS 339
            |....|.|.|.|
 Frog   312 PLNQIIEPSTTS 323

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wrapperNP_477404.1 Ig 41..124 CDD:299845 19/88 (22%)
IG_like 41..118 CDD:214653 17/82 (21%)
IG_like 145..218 CDD:214653 26/73 (36%)
Ig 147..219 CDD:299845 26/72 (36%)
I-set 224..323 CDD:254352 22/98 (22%)
IGc2 236..314 CDD:197706 19/77 (25%)
FN3 339..431 CDD:238020 1/1 (100%)
negr1XP_031755650.1 Ig 44..136 CDD:416386 20/95 (21%)
FR1 44..62 CDD:409353 3/18 (17%)
Ig strand A' 47..53 CDD:409353 1/6 (17%)
Ig strand B 55..63 CDD:409353 3/7 (43%)
CDR1 63..68 CDD:409353 1/4 (25%)
FR2 69..75 CDD:409353 1/5 (20%)
Ig strand C 69..74 CDD:409353 1/4 (25%)
CDR2 76..87 CDD:409353 0/10 (0%)
Ig strand C' 78..82 CDD:409353 0/3 (0%)
Ig strand C' 84..87 CDD:409353 0/2 (0%)
FR3 88..122 CDD:409353 10/35 (29%)
Ig strand D 91..98 CDD:409353 1/6 (17%)
Ig strand E 101..107 CDD:409353 2/5 (40%)
Ig strand F 114..122 CDD:409353 3/7 (43%)
CDR3 123..127 CDD:409353 0/3 (0%)
Ig strand G 127..136 CDD:409353 2/9 (22%)
FR4 129..136 CDD:409353 2/7 (29%)
Ig_3 140..208 CDD:404760 25/72 (35%)
Ig strand A' 146..151 CDD:409353 2/4 (50%)
Ig strand B 157..164 CDD:409353 1/6 (17%)
Ig strand C 170..175 CDD:409353 3/8 (38%)
Ig strand C' 177..179 CDD:409353 0/1 (0%)
Ig strand E 187..193 CDD:409353 2/5 (40%)
Ig strand F 200..207 CDD:409353 3/6 (50%)
Ig strand G 214..222 CDD:409353 2/7 (29%)
Ig_3 226..302 CDD:404760 21/88 (24%)
putative Ig strand A 226..232 CDD:409353 1/5 (20%)
Ig strand B 242..246 CDD:409353 0/3 (0%)
Ig strand C 255..259 CDD:409353 0/3 (0%)
Ig strand E 281..285 CDD:409353 1/3 (33%)
Ig strand F 295..300 CDD:409353 2/4 (50%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
11.000

Return to query results.
Submit another query.