Protein Alignment Rtf1 and RTF1

DIOPT Version :9

• Sequence 1: NP_001286717.1
• Gene: Rtf1 / 37554
• FlyBaseID: FBgn0034722
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: NP_011270.1
• Gene: RTF1 / 852607
• SGDID: S000003213
• Length: 558
• Species: Saccharomyces cerevisiae
• Alignment Length: 683
• Identity: 153/683 - (22%)
• Similarity: 269/683 - (39%)
• Gaps: 194/683 - (28%)

  Fly    23 TNLESDLMSLA---KKRKKPQTAAKSSSRSDSDSDWANNKAGAPSSKKKKRQKPSRDSSSSESNW 84
            ::|:.||::||   :..::.|....:|::...::|.:       .|||::.:..|.:
Yeast     2 SDLDEDLLALAGADESEEEDQVLTTTSAKRAKNNDQS-------LSKKRRIEVGSVE-------- 51

  Fly    85 DDDSQDERQPARQSPAQTQQEHKPPEQASQPAQLSEQEEGEVSDSDSDKSKSNSSSSGSDSSSSS 149
            |||.:|:..|.....|....|.   |:.:.|..|    ||:..
Yeast    52 DDDEEDDYNPYSVGNADYGSEE---EEEANPFPL----EGKYK---------------------- 87

  Fly   150 SSSDSEFDDGFDDDLMGDDEDRRRLNGLSEKERETEIYKRIEQREIMRTRWEIERKLKLAR-RGE 213
                             |:.||..|..|.|.||||.::   |:.:||: ::: ||||..|| |..
Yeast    88 -----------------DESDREHLESLPEMERETLLF---ERSQIMQ-KYQ-ERKLFRARGRDM 130

  Fly   214 KNQEKSKNKGERAKKKKEKREKKARKAREAQAPLPTQASTSTLLDVEPKPSNEVRSASPLSTPAL 278
            |.|:      :|||..::.|:              |:|||
Yeast   131 KEQQ------QRAKNDEDSRK--------------TRAST------------------------- 150

  Fly   279 NRDAASTSAAVASIMPDDAASSAGVSDYFDHKERSKERKKNVEANKTDDKRSNAMALLKAKREGK 343
                .||.|             .|.||                              :||.:..:
Yeast   151 ----RSTHA-------------TGHSD------------------------------IKASKLSQ 168

  Fly   344 AKREEEEAKRMAEKDRDDDKEELDSVSGCKSAVKLKASEIYSDDSGSSDWDEEE-KPAGKRSRSN 407
            .|::.....|....:.|:|.|| |           ...|.|.||.||...|:|| .|..:|...:
Yeast   169 LKKQRARKNRHYSDNEDEDDEE-D-----------YREEDYKDDEGSEYGDDEEYNPFDRRDTYD 221

  Fly   408 SSKASSESEDEEKAPQRPVFITTREDLNKLRLSRYKMERFVNLPIFESTVLNCFVRISIGNNGQ- 471
            ..:....:|:|::..:.|..    .|.||||:.|..:.:|...|.||..|..|:.|:::|.:.:
Yeast   222 KREEVEWAEEEDEQDREPEI----SDFNKLRIGRSFVAKFCFYPGFEDAVKGCYGRVNVGTDKRT 282

  Fly   472 -KPVYRVAEIVGVVETGKIYSLGTTRTNRGLRLKHGTQERVFRLEFISNQEFTENEFNKWNEVCQ 535
             |..||:..|..|. ..|.|::|...||:...:..|...:||::.:.|:..|.|:|:.::.....
Yeast   283 GKTSYRMVRIERVF-LQKPYNMGKFYTNQYFGVTQGKDRKVFQMNYFSDGLFAEDEYQRYLRALD 346

  Fly   536 QSHVQMPTIDLIAIKQNDIKKALNYEFKDEDVDKIVEEKNRFRNR--PTNYAMKKTCLM-KERDA 597
            .|.:..|::..::.|..::...:|....|:..|::|..:.:|..:  .||..::||.|. |.:.|
Yeast   347 NSQMIKPSLHSLSNKTKEVMDFVNTPLTDKTTDEVVRHRMQFNKKLSGTNAVLEKTVLREKLQYA 411

  Fly   598 AMLRGDYDIAQDLGQQIDELENRASELDKRRSH---TLNLISYINDRNRK---KNVEDAEKAILE 656
            .....:.|||: ...|:...|.|.|..:|...:   .:..:..:..:|||   .|:.:||....|
Yeast   412 KETNNEKDIAK-YSAQLRNFEKRMSVYEKHHENDQSDIKKLGELTSKNRKLNMSNIRNAEHVKKE 475

  Fly   657 EARANKGLKISDPFTRRITQPRMGFKGAKKDED 689
            :  :|.....||||:|..|:.::.::..:|:|:
Yeast   476 D--SNNFDSKSDPFSRLKTRTKVYYQEIQKEEN 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtf1	NP_001286717.1	Plus3	428..535	CDD:197843	31/108 (29%)
RTF1	NP_011270.1	COG5296	1..558	CDD:227615	153/683 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	55	1.000	Domainoid score	I2730
eggNOG	1	0.900	-	-		E1_COG5296
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55546
OrthoFinder	1	1.000	-	-		FOG0003630
OrthoInspector	1	1.000	-	-		oto99987
orthoMCL	1	0.900	-	-		OOG6_103917
Panther	1	1.100	-	-	LDO	PTHR13115
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1264
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.850