Protein Alignment Rtf1 and RTF1

DIOPT Version :10

• Sequence 1: NP_611665.1
• Gene: Rtf1 / 37554
• FlyBaseID: FBgn0034722
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: NP_011270.1
• Gene: RTF1 / 852607
• SGDID: S000003213
• Length: 558
• Species: Saccharomyces cerevisiae
• Alignment Length: 620
• Identity: 146/620 - (23%)
• Similarity: 254/620 - (40%)
• Gaps: 144/620 - (23%)

  Fly    86 DDSQDERQPARQSPAQTQQEHKPPEQASQPAQLSEQEEGEVSDSDSDKSKSNSSSSGSDSSSSSS 150
            |:|::|.|....:.|:..:.:  .:..|:..::   |.|.|.|.|.:...:..|...:|..|...
Yeast    15 DESEEEDQVLTTTSAKRAKNN--DQSLSKKRRI---EVGSVEDDDEEDDYNPYSVGNADYGSEEE 74

  Fly   151 SSDSEFDDGFDDDLMG---DDEDRRRLNGLSEKERETEIYKRIEQREIMRTRWEIERKLKLAR-R 211
            ...:.|      .|.|   |:.||..|..|.|.||||.::   |:.:||: ::: ||||..|| |
Yeast    75 EEANPF------PLEGKYKDESDREHLESLPEMERETLLF---ERSQIMQ-KYQ-ERKLFRARGR 128

  Fly   212 GEKNQEKSKNKGERAKKKKEKREKKARKAREAQAPLPTQASTSTLLDVEPKPSNEVRSASPLSTP 276
            ..|.|:      :|||..::.|:              |:|||
Yeast   129 DMKEQQ------QRAKNDEDSRK--------------TRAST----------------------- 150

  Fly   277 ALNRDAASTSAAVASIMPDDAASSAGVSDYFDHKERSKERKKNVEANKTDDKRSNAMALLKAKRE 341
                  .||.|             .|.||                              :||.:.
Yeast   151 ------RSTHA-------------TGHSD------------------------------IKASKL 166

  Fly   342 GKAKREEEEAKRMAEKDRDDDKEELDSVSGCKSAVKLKASEIYSDDSGSSDWDEEE-KPAGKRSR 405
            .:.|::.....|....:.|:|.|| |           ...|.|.||.||...|:|| .|..:|..
Yeast   167 SQLKKQRARKNRHYSDNEDEDDEE-D-----------YREEDYKDDEGSEYGDDEEYNPFDRRDT 219

  Fly   406 SNSSKASSESEDEEKAPQRPVFITTREDLNKLRLSRYKMERFVNLPIFESTVLNCFVRISIGNNG 470
            .:..:....:|:|::..:.|..    .|.||||:.|..:.:|...|.||..|..|:.|:::|.:.
Yeast   220 YDKREEVEWAEEEDEQDREPEI----SDFNKLRIGRSFVAKFCFYPGFEDAVKGCYGRVNVGTDK 280

  Fly   471 Q--KPVYRVAEIVGVVETGKIYSLGTTRTNRGLRLKHGTQERVFRLEFISNQEFTENEFNKWNEV 533
            :  |..||:..|..|. ..|.|::|...||:...:..|...:||::.:.|:..|.|:|:.::...
Yeast   281 RTGKTSYRMVRIERVF-LQKPYNMGKFYTNQYFGVTQGKDRKVFQMNYFSDGLFAEDEYQRYLRA 344

  Fly   534 CQQSHVQMPTIDLIAIKQNDIKKALNYEFKDEDVDKIVEEKNRFRNR--PTNYAMKKTCLM-KER 595
            ...|.:..|::..::.|..::...:|....|:..|::|..:.:|..:  .||..::||.|. |.:
Yeast   345 LDNSQMIKPSLHSLSNKTKEVMDFVNTPLTDKTTDEVVRHRMQFNKKLSGTNAVLEKTVLREKLQ 409

  Fly   596 DAAMLRGDYDIAQDLGQQIDELENRASELDKRRSH---TLNLISYINDRNRK---KNVEDAEKAI 654
            .|.....:.|||: ...|:...|.|.|..:|...:   .:..:..:..:|||   .|:.:||...
Yeast   410 YAKETNNEKDIAK-YSAQLRNFEKRMSVYEKHHENDQSDIKKLGELTSKNRKLNMSNIRNAEHVK 473

  Fly   655 LEEARANKGLKISDPFTRRITQPRMGFKGAKKDED 689
            .|:  :|.....||||:|..|:.::.::..:|:|:
Yeast   474 KED--SNNFDSKSDPFSRLKTRTKVYYQEIQKEEN 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rtf1	NP_611665.1	COG5296	<433..677	CDD:227615	68/254 (27%)
		Plus-3	434..534	CDD:460817	30/101 (30%)
RTF1	NP_011270.1	COG5296	1..558	CDD:227615	146/620 (24%)