DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rtf1 and VIP5

DIOPT Version :9

Sequence 1:	NP_001286717.1	Gene:	Rtf1 / 37554	FlyBaseID:	FBgn0034722	Length:	775	Species:	Drosophila melanogaster
Sequence 2:	NP_001322666.1	Gene:	VIP5 / 842395	AraportID:	AT1G61040	Length:	643	Species:	Arabidopsis thaliana

Alignment Length:	795	Identity:	180/795 - (22%)
Similarity:	312/795 - (39%)	Gaps:	242/795 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 AGAPSSKKKKRQKPS---RDSSSSESNWD--DDSQDERQPARQSPAQTQQEHKPPEQASQPAQLS 119
            ||..:|..:.|..||   |:.|.|:.:.|  |||.::|..|.:.|:.:|...|...:|.:..: :
plant    12 AGRTNSAGRSRHPPSSRRREGSYSDGSSDSRDDSDEDRGYASRKPSGSQVPLKKRLEAEREDR-A 75

  Fly   120 EQEEGEVSDSDSDKSKSNSSSSGSDSSSSSSSSDSEFDDGFDDDLMGDDEDRRRLNGLSEKERET 184
            .:.||...|..||:           ...||..||      |.|||..::|||::|.|::|.:||.
plant    76 ARVEGGYGDGPSDR-----------EGDSSEESD------FGDDLYKNEEDRQKLAGMTEFQREM 123

  Fly   185 EIYKRIEQREIMRTRWEIERKLKLARRGEKN-QEKSKNKGERAKKKKEKREKKARKAREAQAPLP 248
            .:.:|.:                  ::|:|| .||.::|.|..|....|:|.:         |||
plant   124 ILSERAD------------------KKGDKNFTEKLRSKRESEKTPVSKKETQ---------PLP 161

  Fly   249 TQASTSTLLDVEPKPSNEVRSASPLSTPALNRDAASTSAAVASIMPDDAASSAGVSDYFDHKERS 313
            .              |..|||:           |.|...|.|.   |||.:
plant   162 A--------------SRGVRSS-----------ARSADRAAAK---DDALN-------------- 184

  Fly   314 KERKKNVEANKTDDKRSNAMALLKAKREGKAKREEEEAKRMAEKDRDDDKEELDSVSGCKSAVKL 378
                                              |..||||.::|               .|...
plant   185 ----------------------------------ELRAKRMKQQD---------------PAALR 200

  Fly   379 KASEIYSDDSGSSDWDE-EEKPAGKRSRSNSSKASSES---------------EDEEKAPQRPVF 427
            |..:.....|||.|:.. :.||....:.|:||::.|:|               .|::::.
plant   201 KLRDASKGGSGSRDFSSTKRKPLASSNLSSSSQSDSDSRSQSDDEGSNGGMLDSDDDRSD----- 260

  Fly   428 ITTREDLNKLRLSRYKMERFVNLPIFESTVLNCFVRISIGNNGQKPVYRVAEI--VGVVETGKIY 490
            :.|.||:.::.:.|.|:.:::..|.||..::.||||:.||.:...|:||:..:  |...:..|.|
plant   261 VPTFEDVKEVTIRRSKLAKWLMEPFFEELIVGCFVRVGIGRSKSGPIYRLCWVKNVDATDPDKTY 325

  Fly   491 SLGTTRTNRGLRLKHGTQERVFR--LEFISNQEFTENEFNKWNEVCQQSHVQMPTIDLIAIKQND 553
            .|....|::.|.:..|.:....|  :..||:....|.|:.:|....::::.:|||...|:.|:..
plant   326 KLENKTTHKYLNVVWGNETSAARWQMAMISDGHPLEEEYRQWIREVERTNGRMPTKQDISEKKEA 390

  Fly   554 IKKALNYEFKDEDVDKIVEEKNRFRNRPTNYAMKKTCLMKERDAAMLRGDYDIAQDLGQQIDELE 618
            |::..::.:..|.|.::::||.....||.|.|.:|..|.||.:.|..:.|     :.|  ::.::
plant   391 IQRTNSFVYSAETVKQMLQEKKSASVRPMNVAAEKDRLRKELEIAQSKND-----EAG--VERIK 448

  Fly   619 NRASELDKRRS------HTLNLISYINDRNRKKNVEDAEKAILEEARANKGLKISDPFTRRITQP 677
            ::..:||..|:      ..|.| :.:|.:||.:|.::|.:.....|....|....|||:||.|:.
plant   449 SKIKQLDASRNKKGVDKKALKL-AEMNKKNRAENFKNASEVKSITASLKAGEAGYDPFSRRWTRS 512

  Fly   678 RMGFKGAKKDEDDMQLAPLPPPPPGKKRPNEAGTSS----------ASVRSTDS----------- 721
            ...:.|..|.:|..:              |||..::          |.|.:|::
plant   513 SNYYNGKNKGKDGEE--------------NEAAVAAAVETNGADAGAGVEATEAALEAAAEAGKL 563

  Fly   722 --------KDYSLYSLHDFDIDLDV--------PLPVNTNSVPKP-------ASKPAETVSKR-- 761
                    :......||:|::.|.:        |..|....:.:.       ..:.||...||
plant   564 IDTRAPIGQGAEHNQLHNFELSLSLTALQKYGGPQGVQKAFMARKQLTEATVGCRVAENDGKRHG 628

  Fly   762 -SLNLEDYKKKRGLI 775
             :|.:.|||::|||:
plant   629 LTLTVSDYKRRRGLL 643

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rtf1	NP_001286717.1	Plus3	428..535	CDD:197843	30/110 (27%)
VIP5	NP_001322666.1	COG5296	70..516	CDD:227615	135/594 (23%)
VIP5	NP_001322666.1	Plus3	261..372	CDD:197843	30/110 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	56	1.000	Domainoid score	I4084
eggNOG	1	0.900	-	-		E1_COG5296
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	129	1.000	Inparanoid score	I1885
OMA	1	1.010	-	-		QHG55546
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003630
OrthoInspector	1	1.000	-	-		otm3579
orthoMCL	1	0.900	-	-		OOG6_103917
Panther	1	1.100	-	-	LDO	PTHR13115
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3500
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830