Protein Alignment Liprin-gamma and Ppfibp2

DIOPT Version :10

• Sequence 1: NP_001097414.1
• Gene: Liprin-gamma / 37552
• FlyBaseID: FBgn0034720
• Length: 1152
• Species: Drosophila melanogaster
• Sequence 2: NP_001094052.1
• Gene: Ppfibp2 / 308918
• RGDID: 1565383
• Length: 876
• Species: Rattus norvegicus
• Alignment Length: 851
• Identity: 230/851 - (27%)
• Similarity: 339/851 - (39%)
• Gaps: 185/851 - (21%)

  Fly   290 SRFHHLHSAPRPEATMKLREENDRLNAELLRLRRLLELSTDGAVGGVDTAPEMEAVASGEGSAAK 354
            |:.:| |||...|.   .:|...||..:...|...:.:.||......:...::|....|......
  Rat    94 SQVNH-HSAASNET---YQERLARLEGDKESLILQVSVLTDQVEAQGEKIRDLEVCLEGHQVKLN 154

  Fly   355 ERIERLESELRSVKNQLLTMRLERKKLRTDKSDLLGQVKQLCASL-----QEKEQELRDFIRNYQ 414
            ...|.|:.||           |.|..|.|.|.||:.:|.:|...|     ::||||.:.  |..:
  Rat   155 AAEEMLQQEL-----------LSRTSLETQKLDLMTEVSELKLKLVGMEKEQKEQEEKQ--RKAE 206

  Fly   415 ERVRETETTNAKISGDRDRERFQL---LKQARDEAERSLALAQQLSARDLQLQRLQEQL------ 470
            |.::|.:....|:. :.:.||.|.   ||..:.|..:   |.:|::.:|.:::||..||
  Rat   207 ELLQELKHLKIKVE-ELENERNQYEWELKATKAEVAQ---LQEQVALKDAEIERLHSQLSRSSAL 267

  Fly   471 --------QEARRQLTGC----LSDQESLHSFAPLTPPSAASGMLSQMAAASGMGGGLAGMRGTT 523
                    ||..|...|.    :::::.......||      |:|:|......:   :...:|::
  Rat   268 HSDHAERDQEIHRLKMGMETLRVANEDKDRRIEELT------GLLNQYLRVKEI---VMATQGSS 323

  Fly   524 EDSGRGNSLSAFSGSLSGGSGATAGDRNSCSNDSGLRNSS--------------DRESTGGELNF 574
            |.:...|. ....||....:..:.........:...|.||              .|.......:.
  Rat   324 ERTLSINE-DEIEGSFRKWNTTSKSPEEVMKQEVSPRCSSPTPGPPPLPQKSLETRAQKKLSCSL 387

  Fly   575 SDGTCDNG-PCITVDPDSISLVSSQNMYQFGTPKERS-------PTL-------SPLNSAAYSRS 624
            .|..|::| .||..:..|          ..|.||:.|       |||       :|...||.|..
  Rat   388 EDLRCESGNKCINGNQTS----------PVGEPKDSSFLAEQKYPTLPGKLSGATPNGEAAKSPP 442

  Fly   625 VEQL-----GSPV----DPEGPGNGAISRKFANASKSG----------PLGARNGRG--GTWGSI 668
            ...|     ||..    |.||.....:.....:::.||          |.|.|:.:|  ..||.|
  Rat   443 TASLQPDSSGSSQPKLRDTEGGWEDIVMTNELSSTSSGTESSPQSPLTPDGKRSPKGIKKFWGKI 507

  Fly   669 SRVFARSRNKNKALSADGVTEYADYSWNPLTEEGYAEKLRLLREA------SQLPIDRWRATQVL 727
            .|  .:|.|.|  ....|:.|:.........    ..:|...|:.      :..|..:|...:|.
  Rat   508 RR--TQSGNFN--TDTPGMVEFRRGGLRATA----GPRLSRTRDTKGQKCDANAPFAQWSTERVC 564

  Fly   728 AWLEVALGMPQYSARCAENVKSGKVLLELNDVELEAGLGLAHPMHRKKLRLAIEEQRRPEMVRYP 792
            .||: ..|:.||.....:.|.||..||.....::|..||:.||:|||||.||::.....:..:..
  Rat   565 TWLQ-DFGLAQYVIFARQWVASGHTLLTATPQDMEKELGIKHPLHRKKLVLAVKAINTKQEEKSA 628

  Fly   793 LITQLGHTWVATEWLPDIGLPQYAEPFVQSLVDARMLDTLSKKELEKFLGVTRKFHQASIVHGIH 857
            |   |.|.|| |.||.|||||||.:.|.:|.||.|||..|:..:| .||.||.:.|..||...||
  Rat   629 L---LDHVWV-TRWLDDIGLPQYKDQFYESRVDGRMLQYLTVNDL-LFLKVTSQLHHLSIKCAIH 688

  Fly   858 VLRIVKYDRQTLAMRRVQSETVDTDPIV-WTNQRFIRWVRSIDLGEYADNLKDSGVHGGLVVLEP 921
            ||.:.|::...|..|......:....:| |:|.|.:.|:||:||.|||.||:.|||||||::|||
  Rat   689 VLHVNKFNPNCLHRRPADESNLSPSEVVQWSNHRVMEWLRSVDLAEYAPNLRGSGVHGGLIILEP 753

  Fly   922 SFSGDTMATALGIPPSKNIIRRHLNTEFDALILPARATLGQGIRSGCGVVPLTGPG-------GL 979
            .|:|||:|..|.|||.|.::||||.|:|:|||.|......:...:.....|||...       |.
  Rat   754 RFTGDTLAMLLNIPPQKTLLRRHLTTKFNALIGPEAEQEKRDKMASPAYTPLTTTAKVRPRKLGF 818

  Fly   980 QHYATTDRRSSGNLRISAWKGSQSSLSKAFRFNSKPHRTGDRSSFGNST------SPTPSYSSSE 1038
            .|:        ||:|                          :..|..||      .|..:.|.|.
  Rat   819 SHF--------GNMR--------------------------KKKFDESTDYICPMEPGDAVSDSH 849

  Fly  1039 GGGGIY 1044
            ...|:|
  Rat   850 RVYGVY 855

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Liprin-gamma	NP_001097414.1	COG4372	<346..>460	CDD:443500	31/121 (26%)
		SAM_kazrin_repeat1	718..787	CDD:188963	24/68 (35%)
		SAM_kazrin_repeat2	796..860	CDD:188966	33/63 (52%)
		SAM_kazrin_repeat3	882..953	CDD:188969	41/71 (58%)
Ppfibp2	NP_001094052.1	SMC_prok_B	59..>316	CDD:274008	58/251 (23%)
		SAM_liprin-beta1,2_repeat1	555..618	CDD:188962	24/63 (38%)
		SAM_liprin-beta1,2_repeat2	629..691	CDD:188965	34/66 (52%)
		SAM_liprin-beta1,2_repeat3	714..785	CDD:188968	41/70 (59%)