Protein Alignment T3dh and ADH4

DIOPT Version :10

• Sequence 1: NP_477209.2
• Gene: T3dh / 37551
• FlyBaseID: FBgn0017482
• Length: 464
• Species: Drosophila melanogaster
• Sequence 2: NP_011258.2
• Gene: ADH4 / 852636
• SGDID: S000003225
• Length: 382
• Species: Saccharomyces cerevisiae
• Alignment Length: 416
• Identity: 102/416 - (24%)
• Similarity: 171/416 - (41%)
• Gaps: 55/416 - (13%)

  Fly    53 FGPGVSAEVGADLRNLGARKVCLVTDKNVVQLPSVKVALDSLARNGINYEVYDETRVEPTDGSMW 117
            ||.|...|....::|...:|..:|||..:..:.........|....:|..:||:|:..|...::.
Yeast    15 FGEGALEETADYIKNKDYKKALIVTDPGIAAIGLSGRVQKMLEERDLNVAIYDKTQPNPNIANVT 79

  Fly   118 HAVEFARGKEFDAFLAIGGGSAMDTAKAANLFSSDANAEFLDYVNCPIGRGKEISVKLKPLIAMP 182
            ..::..:.:..:..::||||||.|.|||..|.::: ..|..||..  :.:.|:.::   ||.|:.
Yeast    80 AGLKVLKEQNSEIVVSIGGGSAHDNAKAIALLATN-GGEIGDYEG--VNQSKKAAL---PLFAIN 138

  Fly   183 TTSGTGSETTGVAIFDYKKLHAKTGISSKFLKPTLAVIDPLHTLSQPQRVMAFAGFDVFCHALES 247
            ||:||.||.|...|...::...|..|....:.|.:||.||......|..:.|..|.|...|.:|:
Yeast   139 TTAGTASEMTRFTIISNEEKKIKMAIIDNNVTPAVAVNDPSTMFGLPPALTAATGLDALTHCIEA 203

  Fly   248 FTAVDYRERGLAPSDPSLRPTYQGRNPVSDVWARFALETIRKNFVNAIYQPDNLEARSQMHLAST 312
            :.:.                   ..||::|..|...::.|.::.|.|.....:.:||:.|..|..
Yeast   204 YVST-------------------ASNPITDACALKGIDLINESLVAAYKDGKDKKARTDMCYAEY 249

  Fly   313 MAGVGFGNAGVHLCHGLSYPISGNVRDYKPKGYSADHALIPHGLSVVISAPAVFE--FTAPACPD 375
            :||:.|.||.:...|.|::.:.|...             :|||:...:..|.|.|  ...|....
Yeast   250 LAGMAFNNASLGYVHALAHQLGGFYH-------------LPHGVCNAVLLPHVQEANMQCPKAKK 301

  Fly   376 RHLEAAQLLGAEVRGVEKADAGRLLADTVRGF--MQRA-GIENGLRELGFSSSDIPALVEGTLPQ 437
            |..|.|...||.....|         :|::..  :.|. .|...|:|||..:.|...|.|..:..
Yeast   302 RLGEIALHFGASQEDPE---------ETIKALHVLNRTMNIPRNLKELGVKTEDFEILAEHAMHD 357

  Fly   438 E-RITKLAPRAQTQENLSQLFEKSME 462
            . .:|.  |...|:|.:..:.:|:.|
Yeast   358 ACHLTN--PVQFTKEQVVAIIKKAYE 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
T3dh	NP_477209.2	HOT	48..461	CDD:341469	101/413 (24%)
ADH4	NP_011258.2	PDDH	5..377	CDD:341467	100/410 (24%)