Protein Alignment KCNG1 and Kcng1

DIOPT Version :9

• Sequence 1: NP_002228.2
• Gene: KCNG1 / 3755
• HGNCID: 6248
• Length: 513
• Species: Homo sapiens
• Sequence 2: NP_001074603.1
• Gene: Kcng1 / 241794
• MGIID: 3616086
• Length: 514
• Species: Mus musculus
• Alignment Length: 514
• Identity: 477/514 - (92%)
• Similarity: 491/514 - (95%)
• Gaps: 1/514 - (0%)

Human     1 MTLLPGDNSDYDYSALSCTSDASFHPAFLPQRQAIKGAFYRRAQRLRPQDEPRQGCQPEDRRRRI 65
            |||||||||.||||||||.||.||||||.||||||||.||||||||||||:..|.|...||||:|
Mouse     1 MTLLPGDNSHYDYSALSCASDTSFHPAFFPQRQAIKGVFYRRAQRLRPQDDLHQSCSLGDRRRQI 65

Human    66 IINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILNVCDDYDVTCNEFFFDRNPGAFGTILTF 130
            |||||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||
Mouse    66 IINVGGIKYSLPWTTLDEFPLTRLGQLKACTNFDDILSVCDDYDVTCNEFFFDRNPGAFGTILTF 130

Human   131 LRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMVEREEEDDALDSEGRD 195
            |||||||||||||||||||||||||||||||||||||||||||||||||:|||||::.||||.::
Mouse   131 LRAGKLRLLREMCALSFQEELLYWGIAEDHLDGCCKRRYLQKIEEFAEMMEREEEEEPLDSEDQE 195

Human   196 SEGPAEGEGRLGRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGH 260
            ||||:..||||.||||||||||||||||||||||||||||||||||||||||||||||||||||.
Mouse   196 SEGPSASEGRLSRCMRRLRDMVERPHSGLPGKVFACLSVLFVTVTAVNLSVSTLPSLREEEEQGQ 260

Human   261 CSQMCHNVFIVESVCVGWFSLEFLLRLIQAPSKFAFLRSPLTLIDLVAILPYYITLLVDGAAAGR 325
            ||||||||||||||||||||||||||.||||||||||||||||||||||||||:||||||||:.|
Mouse   261 CSQMCHNVFIVESVCVGWFSLEFLLRFIQAPSKFAFLRSPLTLIDLVAILPYYVTLLVDGAASSR 325

Human   326 RKPGAGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIAL 390
            |||..||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 RKPSTGNSYLDKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTARRCTREFGLLLLFLCVAIAL 390

Human   391 FAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFP 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   391 FAPLLYVIENEMADSPEFTSIPACYWWAVITMTTVGYGDMVPRSTPGQVVALSSILSGILLMAFP 455

Human   456 VTSIFHTFSRSYLELKQEQERVMFRRAQFLIKTKSQLS-VSQDSDILFGSASSDTRDNN 513
            ||||||||||||||||||||||:.||||:||||||||| :|||||||||||||||||||
Mouse   456 VTSIFHTFSRSYLELKQEQERVLIRRAQYLIKTKSQLSGMSQDSDILFGSASSDTRDNN 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KCNG1	NP_002228.2	BTB_POZ_KCNG1_2	60..173	CDD:349728	110/112 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	184..204		10/19 (53%)
		Ion_trans	227..471	CDD:395416	236/243 (97%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	424..429		4/4 (100%)
Kcng1	NP_001074603.1	BTB_POZ_KCNG1_2	60..173	CDD:349728	110/112 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	180..205		14/24 (58%)
		Ion_trans	227..471	CDD:395416	236/243 (97%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	424..429		4/4 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83968077
Domainoid	1	1.000	463	1.000	Domainoid score	I9012
eggNOG	1	0.900	-	-		E1_COG2126
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20515
Inparanoid	1	1.050	957	1.000	Inparanoid score	I6183
Isobase	0	0.000	Not matched by this tool.
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG39567
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000074
OrthoInspector	1	1.000	-	-		oto122528
orthoMCL	1	0.900	-	-		OOG6_107871
Panther	1	1.100	-	-	LDO	PTHR11537
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6668
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	17.290