Protein Alignment Gp150 and Lrrc15

DIOPT Version :10

• Sequence 1: NP_477049.2
• Gene: Gp150 / 37549
• FlyBaseID: FBgn0013272
• Length: 1076
• Species: Drosophila melanogaster
• Sequence 2: NP_083249.1
• Gene: Lrrc15 / 74488
• MGIID: 1921738
• Length: 579
• Species: Mus musculus
• Alignment Length: 522
• Identity: 134/522 - (25%)
• Similarity: 223/522 - (42%)
• Gaps: 66/522 - (12%)

  Fly   258 CPRFCQCARN-----VNSYLVATCSRLD---MGIQKFGSDITDL---VVTNVGPKYPILMG---- 307
            ||..|.|:|.     ..:.:||..|.|.   |.:|...:.||:|   ...|:.....:.|.
Mouse    25 CPSECTCSRASQVECTGAQIVAMPSPLPWNAMSLQILNTHITELPEDKFLNISALIALKMEKNEL 89

  Fly   308 ----PNFFQNLGLKNVASIKIANCTLEYLHAEAFHGLNELYAVNLTDVGLAIINPDTFVGNKKLR 368
                |..|:|||  ::..:.:||..|:.|....|..:|.|..:.|::..|..|.|..|.....|:
Mouse    90 ANIMPGAFRNLG--SLRHLSLANNKLKNLPVRLFQDVNNLETLLLSNNQLVQIQPAQFSQFSNLK 152

  Fly   369 MLTISGNDLSVMSS--IHYLLKSSSIEELDFSRNNLMELNPKAFSHLSNVVYINLSQNSLKKLPE 431
            .|.:.||:|..:..  ..:|:   .:.:|:...|....|:|:.|.||.|:..:.|.:|.|..:|.
Mouse   153 ELQLYGNNLEYIPEGVFDHLV---GLTKLNLGNNGFTHLSPRVFQHLGNLQVLRLYENRLSDIPM 214

  Fly   432 KAFEKVTLLEELDLSYNSLTELPRDIFNGTTLSILHLKYNTFNGDLHFGTKDLQQLDLSFNSIVQ 496
            ..|:.:..|:||.|..|.:..|...:|:                    ..::||:|.||.|.|..
Mouse   215 GTFDALGNLQELALQENQIGTLSPGLFH--------------------NNRNLQRLYLSNNHISH 259

  Fly   497 VHHSMFDKMPGLTNLNLKGNGIKKIQPDSFLTLKNLRHIDLSINDLDQISGMLFFKNSELDVIRL 561
            :...:|.::|.|..|.|.||.:|::.|..|..:.|||.:.|..|.:..:....|...::|.|:.|
Mouse   260 LPPGIFMQLPHLNKLTLFGNSLKELSPGVFGPMPNLRELWLYNNHITSLPDNAFSHLNQLQVLIL 324

  Fly   562 NDNPRLSQLPTDGFLSYSGEFTVYYLDISNCAIGPLGHKAFSTMPHLTTLKLAWNNINHLPREIF 626
            :.| :||.:....|   :|...:..|.:...|:..|....|.::.:|..:.|..|.:..||..||
Mouse   325 SHN-QLSYISPGAF---NGLTNLRELSLHTNALQDLDGNVFRSLANLRNVSLQNNRLRQLPGSIF 385

  Fly   627 TGLHKLIDLDLSNNLITRMDDLIFMDNGELTKLSLAGNPISRLSVRLFLPLHQLRCLDVNDCELT 691
            ..::.|:.:.|.||.:..:...||...|.|.:|.|..|| .|....: ||||.  .|.:|...|.
Mouse   386 ANVNGLMTIQLQNNNLENLPLGIFDHLGNLCELRLYDNP-WRCDSNI-LPLHD--WLILNRARLG 446

  Fly   692 T----LLSDRDLGAGYKIFDSLRSFNASGNLIK-----KISS-EDVKSFKNLRSLDITNNPLKCT 746
            |    :.|......|..:.  :.:.|..|..::     ::|| .|..|:.:..|:..|....:.|
Mouse   447 TDTLPVCSSPASVRGQSLV--IINVNFPGPSVQGPETPEVSSYPDTSSYPDSTSISSTTEITRST 509

  Fly   747 PD 748
            .|
Mouse   510 DD 511

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gp150	NP_477049.2	LRR	341..758	CDD:443914	108/420 (26%)
		leucine-rich repeat	343..366	CDD:275380	6/22 (27%)
		leucine-rich repeat	367..391	CDD:275380	6/25 (24%)
		leucine-rich repeat	393..415	CDD:275380	7/21 (33%)
		leucine-rich repeat	416..439	CDD:275380	5/22 (23%)
		leucine-rich repeat	440..483	CDD:275380	7/42 (17%)
		leucine-rich repeat	463..481	CDD:275380	0/17 (0%)
		leucine-rich repeat	484..507	CDD:275380	8/22 (36%)
		leucine-rich repeat	508..531	CDD:275380	8/22 (36%)
		leucine-rich repeat	532..569	CDD:275380	10/36 (28%)
		leucine-rich repeat	556..583	CDD:275380	8/26 (31%)
		leucine-rich repeat	570..607	CDD:275380	6/36 (17%)
		leucine-rich repeat	608..631	CDD:275380	7/22 (32%)
		leucine-rich repeat	632..655	CDD:275380	6/22 (27%)
		leucine-rich repeat	656..674	CDD:275380	6/17 (35%)
		leucine-rich repeat	733..745	CDD:275378	2/11 (18%)
Lrrc15	NP_083249.1	LRR_8	54..113	CDD:404697	14/60 (23%)
		LRR 1	54..75		5/20 (25%)
		leucine-rich repeat	58..78	CDD:275380	5/19 (26%)
		LRR 2	78..99		3/20 (15%)
		LRR 3	102..123		5/20 (25%)
		LRR	103..>441	CDD:443914	98/368 (27%)
		leucine-rich repeat	103..126	CDD:275380	5/22 (23%)
		LRR 4	126..147		6/20 (30%)
		leucine-rich repeat	127..150	CDD:275380	6/22 (27%)
		LRR 5	150..171		5/20 (25%)
		leucine-rich repeat	151..174	CDD:275380	6/25 (24%)
		LRR 6	174..195		5/20 (25%)
		leucine-rich repeat	175..198	CDD:275380	7/22 (32%)
		LRR 7	198..219		6/20 (30%)
		leucine-rich repeat	199..222	CDD:275380	5/22 (23%)
		LRR 8	222..243		7/40 (18%)
		leucine-rich repeat	223..246	CDD:275380	7/42 (17%)
		LRR 9	246..267		8/20 (40%)
		leucine-rich repeat	247..270	CDD:275380	8/22 (36%)
		LRR 10	270..291		8/20 (40%)
		leucine-rich repeat	271..294	CDD:275380	8/22 (36%)
		LRR 11	294..315		6/20 (30%)
		leucine-rich repeat	295..318	CDD:275380	5/22 (23%)
		LRR 12	318..339		7/24 (29%)
		leucine-rich repeat	319..342	CDD:275380	8/26 (31%)
		LRR 13	342..363		4/20 (20%)
		leucine-rich repeat	343..364	CDD:275380	4/20 (20%)
		LRR 14	366..387		7/20 (35%)
		leucine-rich repeat	367..387	CDD:275380	7/19 (37%)
		LRR 15	390..411		6/20 (30%)
		leucine-rich repeat	391..412	CDD:275380	6/20 (30%)
		LRRCT	423..>462	CDD:214507	12/42 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..509		6/32 (19%)