DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gp150 and atk

DIOPT Version :9

Sequence 1:NP_477049.2 Gene:Gp150 / 37549 FlyBaseID:FBgn0013272 Length:1076 Species:Drosophila melanogaster
Sequence 2:NP_001262113.1 Gene:atk / 40266 FlyBaseID:FBgn0036995 Length:1535 Species:Drosophila melanogaster


Alignment Length:624 Identity:152/624 - (24%)
Similarity:236/624 - (37%) Gaps:168/624 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   311 FQNL-GLKNVASIKIANCTLEYLHAEAFHGLNELYAVNLTDVGLAIINPDTFVGNKKLRMLTISG 374
            |.|| |||   .:.:|......:.::...||..|..::|::.||..:.|::|..|..|..|.||.
  Fly   426 FWNLPGLK---GLDLAQNQFARVDSQLLAGLPSLRRLDLSENGLIELAPNSFRHNPLLETLNISS 487

  Fly   375 NDLSVMSS---IHY-----------LLKS------SSIEELDFSRNNLMELNPKAFS---HLSNV 416
            |:|:.:.|   ||.           .|||      ..:|.:....|.:..| |.|.|   .|.|:
  Fly   488 NELTKIHSSTLIHLERLFEVDASYNQLKSVIAGLPRIVERISLKGNQITSL-PAAASKDLQLPNL 551

  Fly   417 VYINLSQNSLKKLPEKAFEKVTLLEELDLSYNSLTELPRDIFNG-TTLSILHLKYNTFN------ 474
            ..::||||.:::||...|:....|..|.|:.|.|.:|....|.| ..|.:|||:.|...      
  Fly   552 RMLDLSQNRIEQLPRHGFQGAMELRVLSLAQNELRQLKDTSFIGIQRLELLHLQENQLGEADERA 616

  Fly   475 --------------------GDLHFGTKD-LQQLDLSFNSIVQVHHSMFDKMPGLTNLNLKGNGI 518
                                .|..|.... |:|||||.|.|..:..:.||....|..|:|.||.:
  Fly   617 LLPLAELRNLNLQSNKLEAITDNFFSNNSRLEQLDLSRNLIRSISPTAFDTQRSLEYLDLSGNAL 681

  Fly   519 KKIQPDSFLTLKNLRHIDLSINDLDQISGMLFFKNSELDVIRLNDN--PRLSQLPTDGFLSYSGE 581
            ..|.. ....|.|||.||||.|.:.:|...:......:..|||::|  ..|.|          |.
  Fly   682 LDISV-GLGNLNNLRDIDLSYNQISRIQSDVIGGWRNVVEIRLSNNLIVELQQ----------GT 735

  Fly   582 F----TVYYLDISNCAIG------------------------PLGHKAFSTMPHLTTLKLAWNNI 618
            |    .:.|||:|:..|.                        .|....|..:|.|......:|.:
  Fly   736 FRNLPKLQYLDLSSNEIRNVEPGALKGLDELQEFVLADNKLVELKDHVFEELPSLLASHFQYNKL 800

  Fly   619 NHLPREIFTGLHKLIDLDLSNNLITRMDDLIFMDNGELTKLSLAGNPISRLSVRLFLPLHQLRCL 683
            .::..|.|...:.|:.|:||||....|:::.......|..|.|:.|.:..:|.   :||..|..|
  Fly   801 RYISPESFHNANSLVFLNLSNNHFRNMENIGLRSMRNLEVLDLSTNGVKLVST---MPLKALNWL 862

  Fly   684 -----DVND-CELTTLLSDRDLGAGYKIFDSLRSFNASGNLIKKISSEDVKSFKNLRS----LDI 738
                 |.|. |.:.        |:.::....||..:...|.::.|..   ::|:|:|.    ||:
  Fly   863 VELKMDNNQICRIQ--------GSPFETMPRLRVLSMRNNQLRSIKE---RTFRNVRGNIAILDV 916

  Fly   739 TNNPLKCTPDFQEFISYVTLQMQMT------PK----RLPVLANLEDDATIVQLETLAQAGWSSL 793
            ..||:.|..:.|    ::::.:|.|      ||    ||...|.:|....:              
  Fly   917 DGNPIDCNCEMQ----WLSVWLQETNFPYPGPKCQDGRLLRSARMERSLCV-------------- 963

  Fly   794 AHEVCKHAEGSDLLDEKKADSAEAKLEKRLKESVKKLNE 832
                     |:|:...::.|..:..|          |||
  Fly   964 ---------GADIYGNERTDGNQLPL----------LNE 983

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gp150NP_477049.2 LRR_8 317..377 CDD:290566 16/59 (27%)
leucine-rich repeat 343..366 CDD:275380 7/22 (32%)
leucine-rich repeat 367..391 CDD:275380 12/43 (28%)
LRR_RI <374..619 CDD:238064 82/325 (25%)
LRR_8 390..450 CDD:290566 19/62 (31%)
leucine-rich repeat 393..415 CDD:275380 7/24 (29%)
leucine-rich repeat 416..439 CDD:275380 7/22 (32%)
leucine-rich repeat 440..483 CDD:275380 15/69 (22%)
leucine-rich repeat 463..481 CDD:275380 7/43 (16%)
LRR_8 484..542 CDD:290566 25/57 (44%)
leucine-rich repeat 484..507 CDD:275380 10/22 (45%)
leucine-rich repeat 508..531 CDD:275380 7/22 (32%)
leucine-rich repeat 532..569 CDD:275380 13/38 (34%)
leucine-rich repeat 556..583 CDD:275380 8/32 (25%)
leucine-rich repeat 570..607 CDD:275380 9/64 (14%)
LRR_RI <586..745 CDD:238064 43/192 (22%)
LRR_8 606..666 CDD:290566 16/59 (27%)
leucine-rich repeat 608..631 CDD:275380 4/22 (18%)
leucine-rich repeat 632..655 CDD:275380 7/22 (32%)
leucine-rich repeat 656..674 CDD:275380 5/17 (29%)
leucine-rich repeat 733..745 CDD:275378 5/15 (33%)
atkNP_001262113.1 leucine-rich repeat 69..89 CDD:275380
leucine-rich repeat 90..113 CDD:275380
leucine-rich repeat 115..138 CDD:275380
leucine-rich repeat 139..160 CDD:275380
leucine-rich repeat 161..184 CDD:275380
LRR_8 183..244 CDD:290566
leucine-rich repeat 185..209 CDD:275380
LRR_4 209..247 CDD:289563
leucine-rich repeat 210..233 CDD:275380
leucine-rich repeat 234..259 CDD:275380
LRR_RI 250..492 CDD:238064 22/68 (32%)
LRR_8 259..318 CDD:290566
leucine-rich repeat 260..283 CDD:275380
leucine-rich repeat 284..307 CDD:275380
leucine-rich repeat 308..359 CDD:275380
leucine-rich repeat 334..348 CDD:275378
LRR_8 358..418 CDD:290566
leucine-rich repeat 360..383 CDD:275380
leucine-rich repeat 384..407 CDD:275380
LRR_8 406..466 CDD:290566 11/42 (26%)
leucine-rich repeat 408..431 CDD:275380 3/4 (75%)
leucine-rich repeat 432..455 CDD:275380 5/25 (20%)
LRR_RI 447..705 CDD:238064 76/259 (29%)
LRR_8 454..514 CDD:290566 16/59 (27%)
leucine-rich repeat 456..476 CDD:275380 6/19 (32%)
leucine-rich repeat 480..501 CDD:275380 8/20 (40%)
leucine-rich repeat 505..517 CDD:275378 2/11 (18%)
leucine-rich repeat 525..550 CDD:275380 7/25 (28%)
LRR_8 549..609 CDD:290566 21/59 (36%)
leucine-rich repeat 551..574 CDD:275380 7/22 (32%)
leucine-rich repeat 575..598 CDD:275380 8/22 (36%)
leucine-rich repeat 599..622 CDD:275380 5/22 (23%)
LRR_8 622..681 CDD:290566 17/58 (29%)
leucine-rich repeat 623..646 CDD:275380 2/22 (9%)
LRR_RI 647..896 CDD:238064 69/270 (26%)
leucine-rich repeat 647..670 CDD:275380 10/22 (45%)
leucine-rich repeat 671..693 CDD:275380 7/22 (32%)
leucine-rich repeat 694..717 CDD:275380 8/22 (36%)
LRR_8 716..776 CDD:290566 13/69 (19%)
leucine-rich repeat 718..741 CDD:275380 8/32 (25%)
leucine-rich repeat 742..763 CDD:275380 5/20 (25%)
LRR_8 765..824 CDD:290566 13/58 (22%)
leucine-rich repeat 766..789 CDD:275380 2/22 (9%)
leucine-rich repeat 790..813 CDD:275380 4/22 (18%)
leucine-rich repeat 814..835 CDD:275380 7/20 (35%)
leucine-rich repeat 838..861 CDD:275380 8/25 (32%)
LRR_8 862..921 CDD:290566 15/69 (22%)
leucine-rich repeat 862..885 CDD:275380 5/30 (17%)
leucine-rich repeat 886..906 CDD:275380 5/22 (23%)
TPKR_C2 919..>946 CDD:301599 7/30 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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