DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gp150 and CG4781

DIOPT Version :9

Sequence 1:	NP_477049.2	Gene:	Gp150 / 37549	FlyBaseID:	FBgn0013272	Length:	1076	Species:	Drosophila melanogaster
Sequence 2:	NP_611951.1	Gene:	CG4781 / 37943	FlyBaseID:	FBgn0035043	Length:	469	Species:	Drosophila melanogaster

Alignment Length:	350	Identity:	86/350 - (24%)
Similarity:	144/350 - (41%)	Gaps:	71/350 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   440 LEELDLSYNSLTELPRDIFNGTTLSILHLKYNTFNGDLHFGTKDLQQLDLSFNSIVQVHHSMFDK 504
            ::.||||:|:|..:|                 .|..|      .|.||:|..|:|.|:....|.:
  Fly    88 IDSLDLSWNALDSVP-----------------IFTSD------SLHQLNLRHNNISQLVSGNFKQ 129

  Fly   505 MPGLTNLNLKGNGIKKIQPDSFLTLKNLRHIDLSINDLDQISGMLFFKNSELDVIRLNDNPRLSQ 569
            :..|..|.|..|.|.|::..||..|.:|:.:||:.|:|..:.|.||.....|..:.::.|.|.::
  Fly   130 LTSLRELYLGWNSIGKLESGSFDGLPHLQVLDLAHNNLHLLPGHLFAPLLVLGTLDISWNRRFNE 194

  Fly   570 LPTDGFLSYSGEFTVYYLDISNCAIGPLGHKAFSTMPHLTTLKLAWNNINHLPREIFTGLHKLID 634
            ...|.:......:.:..|.:..|::..| |...:.  .|..|.|..|.:..:|.::   ...|:.
  Fly   195 SGGDLYTGLGVNWKLSTLRLDACSLNDL-HLPVNA--PLKELSLRRNQLKRIPTQL---PETLLR 253

  Fly   635 LDLSNNLITRMDDLIFMDNGELTKL------------SLAGNPISRLSVRLFLPLHQLRCLDVND 687
            ||:|:||   :::|:..|...||::            .:..|.::.:.|...|.....|.|...|
  Fly   254 LDISDNL---LEELLPEDTANLTQVRQLFIEDMPVLQRVVANSLTHVDVLETLSFQNSRQLSHLD 315

  Fly   688 CE-----LTTLLSDRDLGAGYKIFDSLRSFNASGNLIKKISSEDVKSFKNLRSLDITNNPLKCTP 747
            .|     :||....|          :|||.:..|.:::..:|.....|..|..||:...||:|..
  Fly   316 AEAFGPIMTTPTKKR----------ALRSLSFRGTMLRTFNSTLAPIFTQLAELDLNGLPLQCDC 370

  Fly   748 DFQEFISYVTLQMQMTPKRLPVLAN 772
            :.      |.|      |:|||..|
  Fly   371 EL------VWL------KQLPVQTN 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gp150	NP_477049.2	LRR_8	317..377	CDD:290566
		leucine-rich repeat	343..366	CDD:275380
		leucine-rich repeat	367..391	CDD:275380
		LRR_RI	<374..619	CDD:238064	46/178 (26%)
		LRR_8	390..450	CDD:290566	5/9 (56%)
		leucine-rich repeat	393..415	CDD:275380
		leucine-rich repeat	416..439	CDD:275380
		leucine-rich repeat	440..483	CDD:275380	9/42 (21%)
		leucine-rich repeat	463..481	CDD:275380	2/17 (12%)
		LRR_8	484..542	CDD:290566	21/57 (37%)
		leucine-rich repeat	484..507	CDD:275380	8/22 (36%)
		leucine-rich repeat	508..531	CDD:275380	9/22 (41%)
		leucine-rich repeat	532..569	CDD:275380	11/36 (31%)
		leucine-rich repeat	556..583	CDD:275380	4/26 (15%)
		leucine-rich repeat	570..607	CDD:275380	5/36 (14%)
		LRR_RI	<586..745	CDD:238064	40/175 (23%)
		LRR_8	606..666	CDD:290566	16/71 (23%)
		leucine-rich repeat	608..631	CDD:275380	5/22 (23%)
		leucine-rich repeat	632..655	CDD:275380	8/22 (36%)
		leucine-rich repeat	656..674	CDD:275380	4/29 (14%)
		leucine-rich repeat	733..745	CDD:275378	5/11 (45%)
CG4781	NP_611951.1	leucine-rich repeat	90..108	CDD:275380	9/40 (23%)
		LRR_8	108..167	CDD:290566	21/58 (36%)
		leucine-rich repeat	109..132	CDD:275380	8/22 (36%)
		LRR_RI	<121..>261	CDD:238064	38/148 (26%)
		leucine-rich repeat	133..156	CDD:275380	9/22 (41%)
		leucine-rich repeat	157..180	CDD:275380	8/22 (36%)
		leucine-rich repeat	181..208	CDD:275380	4/26 (15%)
		leucine-rich repeat	230..253	CDD:275380	6/25 (24%)
		leucine-rich repeat	254..274	CDD:275380	8/22 (36%)
		leucine-rich repeat	275..299	CDD:275380	1/23 (4%)
		leucine-rich repeat	300..319	CDD:275380	5/18 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR45617
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100