DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Gp150 and CG4168

DIOPT Version :9

Sequence 1:NP_477049.2 Gene:Gp150 / 37549 FlyBaseID:FBgn0013272 Length:1076 Species:Drosophila melanogaster
Sequence 2:NP_001285953.1 Gene:CG4168 / 34889 FlyBaseID:FBgn0028888 Length:1330 Species:Drosophila melanogaster


Alignment Length:689 Identity:171/689 - (24%)
Similarity:307/689 - (44%) Gaps:127/689 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   271 YLVATCSRLDM--GIQKFGSDITDLVVT-NVGPKYPILMGPNFFQ----NLGL------------ 316
            ||..|.:::..  .:..|..::..|.:: |.....|:|...|:.|    |:|.            
  Fly   439 YLYLTSNQISQLNNLPSFTENLRVLSLSGNNFSMIPVLGLKNYTQLSYLNMGYNSITDIPEGIFA 503

  Fly   317 -----KNVASIKIANCTLEYLHAEAFHGLNELYAVNLTDVGLAIINPDTFVG-NKKLRMLTIS-- 373
                 .|:.:|.:.|..:.:||..:|.||.::..::|:...:.|.:|..|.. ::.|::|.:|  
  Fly   504 VDSWGSNLQTILLRNNKITHLHLGSFAGLEQIQEISLSFNDITIHHPLVFENVSRTLKILELSFA 568

  Fly   374 ---GNDLSVMSSIHYLLKSSSIEELDFSRNNLMELNPKAFSHLSNVVYINLSQNSLKKLPEKAFE 435
               ...|..:..:..||..|.:..|....|||.:::.::|:.:..:.|||||.|.||.||...|:
  Fly   569 VFPARSLESLDPLDALLPLSQLIWLGLDNNNLKQVSNESFAQMRELSYINLSFNQLKTLPRGLFQ 633

  Fly   436 K--VTLLEELDLSYNSLTELPRDIFNG----TTLSILHLKYNTFNGDLHFGTKDLQQLDLSFNSI 494
            .  .:.|.|:|||||.|..|....|:.    .||::...:..|.........:.|:.||||:|.:
  Fly   634 SDAHSHLVEIDLSYNGLERLEAQTFHSLGDLQTLNLQSNRLRTIARHAFHNLEFLRYLDLSYNRL 698

  Fly   495 VQVHHSMFDKMPGLTNLNLKGNGIKKIQPDSFLTLKN----LRHIDLSINDL----DQISGMLFF 551
            |.:.|..|..:|.|..|:|..|.:..:...|||.:.|    || :::|.|.:    |::|..::.
  Fly   699 VNISHGAFTVLPNLAALDLMHNQLCSLSLKSFLYVSNTTTPLR-LNVSHNHIASFYDELSSYMYI 762

  Fly   552 KNSELDVIRLNDNPRLSQLPTDGFLSYSGEFTVYYLDISNCAIGPLGHKAFSTMPHLTTLKLAWN 616
              .:||:    .:..:::  :|.|.:.:.  |:.:|::::..:|.|...||..:..|..|.:|.|
  Fly   763 --YQLDI----SHNHVTK--SDSFTNLAN--TLRFLNLAHNQLGSLQSHAFGDLEFLEILNVAHN 817

  Fly   617 NINHLPREIFTGLHKLIDLDLSNNLITRMDDLIFMDNGELTKLSLAGNPISRLSVRLFLPLHQLR 681
            |:..|.|..|.||:.|.:||||:|.:.::....|.:..:|..|.:..|.:..|...:|:.. :|.
  Fly   818 NLTSLRRRSFQGLNSLQELDLSHNQLDQLQVEQFSNLRKLRILRINSNRLRALPREVFMNT-RLE 881

  Fly   682 CLDVNDCELTT--LLSDRDLGAGYKIFDSLRSFNASGNLIKKISS-------------------- 724
            .||:.:.:|:.  :.:..|:|.      :|||...|.|.::.:.:                    
  Fly   882 FLDIAENQLSVWPVPAFTDIGF------TLRSIQMSHNNLEYLDASMFINSQFLYDISLARNRIT 940

  Fly   725 ---EDVKSF-KNLRSLDITNNPLKCTPDFQEFISYVTLQ---------MQMTPKRLPVLANLEDD 776
               ::..|| .||.:||::.|||..|...:.|:....|:         ..:.|.:||:|:.|  |
  Fly   941 ILPDNTFSFLNNLTNLDLSQNPLVTTNLREVFVHTPRLRKLSLHHMGLYVLPPLKLPLLSYL--D 1003

  Fly   777 ATIVQLETLAQAGWSSLAHEVCKHAEGSDLLDEKKADSAEAKLEKRLKESVKKLN---------- 831
            .:...|:.|:..|  ||.|  .:|..    :...|..:|....| .|..||:.|:          
  Fly  1004 VSGNYLQELSPLG--SLRH--LRHVN----VSHNKLTNASCAAE-HLPPSVRVLDLAHNPLRRIT 1059

  Fly   832 -EDEAKL-----LSVLDKSVLDK---SRLSSMQKIMKGS 861
             .|.|.|     |::||..|.:.   |:|.|::|:...|
  Fly  1060 LHDLASLRHLAELNILDVKVTNPQAFSKLRSLRKLHASS 1098

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gp150NP_477049.2 LRR_8 317..377 CDD:290566 15/65 (23%)
leucine-rich repeat 343..366 CDD:275380 4/23 (17%)
leucine-rich repeat 367..391 CDD:275380 6/28 (21%)
LRR_RI <374..619 CDD:238064 72/258 (28%)
LRR_8 390..450 CDD:290566 24/61 (39%)
leucine-rich repeat 393..415 CDD:275380 5/21 (24%)
leucine-rich repeat 416..439 CDD:275380 11/24 (46%)
leucine-rich repeat 440..483 CDD:275380 13/46 (28%)
leucine-rich repeat 463..481 CDD:275380 2/17 (12%)
LRR_8 484..542 CDD:290566 22/61 (36%)
leucine-rich repeat 484..507 CDD:275380 9/22 (41%)
leucine-rich repeat 508..531 CDD:275380 7/22 (32%)
leucine-rich repeat 532..569 CDD:275380 8/40 (20%)
leucine-rich repeat 556..583 CDD:275380 4/26 (15%)
leucine-rich repeat 570..607 CDD:275380 8/36 (22%)
LRR_RI <586..745 CDD:238064 47/184 (26%)
LRR_8 606..666 CDD:290566 20/59 (34%)
leucine-rich repeat 608..631 CDD:275380 10/22 (45%)
leucine-rich repeat 632..655 CDD:275380 7/22 (32%)
leucine-rich repeat 656..674 CDD:275380 4/17 (24%)
leucine-rich repeat 733..745 CDD:275378 6/11 (55%)
CG4168NP_001285953.1 leucine-rich repeat 99..118 CDD:275380
LRR_8 121..181 CDD:290566
LRR_RI 122..350 CDD:238064
leucine-rich repeat 122..146 CDD:275380
leucine-rich repeat 147..170 CDD:275380
leucine-rich repeat 171..194 CDD:275380
leucine-rich repeat 195..214 CDD:275380
leucine-rich repeat 215..236 CDD:275380
LRR_8 265..322 CDD:290566
leucine-rich repeat 266..287 CDD:275380
leucine-rich repeat 288..311 CDD:275380
leucine-rich repeat 312..338 CDD:275380
LRR_RI 315..546 CDD:238064 21/106 (20%)
leucine-rich repeat 339..365 CDD:275380
LRR_8 365..424 CDD:290566
leucine-rich repeat 366..388 CDD:275380
leucine-rich repeat 389..412 CDD:275380
LRR_8 413..470 CDD:290566 6/30 (20%)
leucine-rich repeat 414..436 CDD:275380
leucine-rich repeat 437..459 CDD:275380 4/19 (21%)
leucine-rich repeat 460..483 CDD:275380 5/22 (23%)
LRR_8 482..545 CDD:290566 12/62 (19%)
leucine-rich repeat 484..510 CDD:275380 2/25 (8%)
leucine-rich repeat 511..534 CDD:275380 7/22 (32%)
leucine-rich repeat 535..589 CDD:275380 10/53 (19%)
LRR_RI 588..891 CDD:238064 89/314 (28%)
LRR_8 588..650 CDD:290566 24/61 (39%)
leucine-rich repeat 590..613 CDD:275380 5/22 (23%)
leucine-rich repeat 614..639 CDD:275380 11/24 (46%)
LRR_8 638..698 CDD:290566 19/59 (32%)
leucine-rich repeat 640..663 CDD:275380 10/22 (45%)
leucine-rich repeat 664..687 CDD:275380 3/22 (14%)
LRR_8 688..749 CDD:290566 22/61 (36%)
leucine-rich repeat 688..711 CDD:275380 9/22 (41%)
leucine-rich repeat 712..735 CDD:275380 7/22 (32%)
leucine-rich repeat 740..783 CDD:275380 10/51 (20%)
LRR_8 784..843 CDD:290566 22/58 (38%)
leucine-rich repeat 785..808 CDD:275380 5/22 (23%)
leucine-rich repeat 809..832 CDD:275380 10/22 (45%)
LRR_RI <827..1053 CDD:238064 58/243 (24%)
LRR_8 832..890 CDD:290566 15/58 (26%)
leucine-rich repeat 833..856 CDD:275380 7/22 (32%)
leucine-rich repeat 857..879 CDD:275380 5/22 (23%)
leucine-rich repeat 880..900 CDD:275380 4/19 (21%)
LRR_8 904..963 CDD:290566 12/58 (21%)
leucine-rich repeat 905..928 CDD:275380 5/22 (23%)
leucine-rich repeat 929..952 CDD:275380 2/22 (9%)
leucine-rich repeat 953..977 CDD:275380 8/23 (35%)
leucine-rich repeat 978..1020 CDD:275380 12/45 (27%)
LRR_8 1019..1074 CDD:290566 13/61 (21%)
leucine-rich repeat 1045..1068 CDD:275380 5/22 (23%)
leucine-rich repeat 1069..1090 CDD:275380 6/20 (30%)
leucine-rich repeat 1091..1114 CDD:275380 2/8 (25%)
leucine-rich repeat 1115..1161 CDD:275380
leucine-rich repeat 1162..1190 CDD:275380
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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