Protein Alignment Gp150 and Gp5

DIOPT Version :10

• Sequence 1: NP_477049.2
• Gene: Gp150 / 37549
• FlyBaseID: FBgn0013272
• Length: 1076
• Species: Drosophila melanogaster
• Sequence 2: NP_036927.2
• Gene: Gp5 / 25259
• RGDID: 2724
• Length: 567
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 135/551 - (24%)
• Similarity: 225/551 - (40%)
• Gaps: 88/551 - (15%)

  Fly   243 LLTDDEQVVFSEDVPCPRFCQCARNVNSYLVATCSRLDMGIQKFGSDITDLVVTNVGPKYPILMG 307
            ||:....:|.::..|||:.|:|.             :...:|..|..:..:.
  Rat     6 LLSAVLSLVGAQPFPCPKTCKCV-------------VRDAVQCSGGSVAHIA------------- 44

  Fly   308 PNFFQNLGL-KNVASIKIANCTLEYLHAEAFHGLNELYAVNLTDVGLAIINPDTFVGNKKLRMLT 371
                 .||| .|:..|.:.......|.:.:|.|:..|..:.|:|..::.|:|.||....||:.|.
  Rat    45 -----ELGLPTNLTHILLFRMDRGVLQSHSFSGMTVLQRLMLSDSHISAIDPGTFNDLVKLKTLR 104

  Fly   372 ISGNDLSVMSSIHYLLKSSSIEELDFSRNNLMELNPKAFSHLSNVVYINLSQNSLKKLPEKAFEK 436
            ::.|.:|.:... .|.|...:|:|....|.|.:|:...|..|.|:..:.|:||.|..||...|..
  Rat   105 LTRNKISHLPRA-ILDKMVLLEQLFLDHNALRDLDQNLFQKLLNLRDLCLNQNQLSFLPANLFSS 168

  Fly   437 VTLLEELDLSYNSLTELPRDIFNGTTLSILHLKYNTFNGDLHFGTKDLQQLDLSFNSIVQVHHSM 501
            :..|:.||||.|:||.||:.:...      .:|              |::|.|..|.::.:...:
  Rat   169 LGKLKVLDLSRNNLTHLPQGLLGA------QIK--------------LEKLLLYSNRLMSLDSGL 213

  Fly   502 FDKMPGLTNLNLKGNGIKKIQPDSFLTLKNLRHIDLSINDLDQISGMLFFKNSELDVIRLNDNPR 566
            ...:..||.|.|:.|.::.|.|.:|.:|.||..:.||.|.|:.:...||...|.:..:.|.:||
  Rat   214 LANLGALTELRLERNHLRSIAPGAFDSLGNLSTLTLSGNLLESLPPALFLHVSCVTRLTLFENP- 277

  Fly   567 LSQLPTDGFLSYSGEFTVYYLDISNCAIGPLGHKAFSTMPHLTTLKLAWNN-INHLPREIFTGLH 630
            |.:||...|...:|   :..|.::...:..|...||..:..|.||.|..|. ::.|||.:|.||.
  Rat   278 LEELPEVLFGEMAG---LRELWLNGTHLRTLPAAAFRNLSGLQTLGLTRNPLLSALPRGMFHGLT 339

  Fly   631 KLIDLDLSNNLITRMDDLIFMDNGELTKLSLAGNPISRLSVRLFLPLHQLRCLDVNDCELTTLLS 695
            :|..|.|..|.:..:.:......|.|.::||..|.:..|...||..|..|..:.:...:|.||..
  Rat   340 ELRVLALHTNALEELPEDALRGLGRLRQVSLRHNRLRALPRTLFRNLSSLVTVQLEHNQLKTLPG 404

  Fly   696 DRDLGAGYKIFDSLRSFNASGNLIKKISSEDVKSFKNLRSLDITNNPLKCTPDFQEFISYVTLQM 760
            |        :|.:|                     ..|..:.:.:||..|......|:.::...:
  Rat   405 D--------VFAAL---------------------PQLTRVLLGHNPWLCDCGLWPFLQWLRHHL 440

  Fly   761 QMTPKRLPVLAN-LEDDATIVQLETLAQAGW 790
            ::..:..|...| .|..|::...|.|....|
  Rat   441 ELLGRDEPPQCNGPESRASLTFWELLQGDQW 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gp150	NP_477049.2	LRR	341..758	CDD:443914	110/417 (26%)
		leucine-rich repeat	343..366	CDD:275380	7/22 (32%)
		leucine-rich repeat	367..391	CDD:275380	6/23 (26%)
		leucine-rich repeat	393..415	CDD:275380	7/21 (33%)
		leucine-rich repeat	416..439	CDD:275380	7/22 (32%)
		leucine-rich repeat	440..483	CDD:275380	11/42 (26%)
		leucine-rich repeat	463..481	CDD:275380	1/17 (6%)
		leucine-rich repeat	484..507	CDD:275380	4/22 (18%)
		leucine-rich repeat	508..531	CDD:275380	9/22 (41%)
		leucine-rich repeat	532..569	CDD:275380	12/36 (33%)
		leucine-rich repeat	556..583	CDD:275380	8/26 (31%)
		leucine-rich repeat	570..607	CDD:275380	8/36 (22%)
		leucine-rich repeat	608..631	CDD:275380	11/23 (48%)
		leucine-rich repeat	632..655	CDD:275380	4/22 (18%)
		leucine-rich repeat	656..674	CDD:275380	5/17 (29%)
		leucine-rich repeat	733..745	CDD:275378	3/11 (27%)
Gp5	NP_036927.2	LRR_8	<64..110	CDD:404697	14/45 (31%)
		LRR 1	75..96		7/20 (35%)
		leucine-rich repeat	76..99	CDD:275380	7/22 (32%)
		LRR	95..424	CDD:443914	101/382 (26%)
		LRR 2	99..120		6/21 (29%)
		leucine-rich repeat	100..123	CDD:275380	6/23 (26%)
		LRR 3	123..144		6/20 (30%)
		leucine-rich repeat	124..147	CDD:275380	7/22 (32%)
		LRR 4	147..168		8/20 (40%)
		leucine-rich repeat	148..171	CDD:275380	7/22 (32%)
		LRR 5	171..193		10/27 (37%)
		leucine-rich repeat	172..195	CDD:275380	10/28 (36%)
		LRR 6	195..216		5/34 (15%)
		leucine-rich repeat	196..219	CDD:275380	4/22 (18%)
		LRR 7	219..240		8/20 (40%)
		leucine-rich repeat	220..243	CDD:275380	9/22 (41%)
		LRR 8	243..264		8/20 (40%)
		leucine-rich repeat	244..267	CDD:275380	7/22 (32%)
		LRR 9	267..288		7/21 (33%)
		leucine-rich repeat	268..291	CDD:275380	7/23 (30%)
		LRR 10	291..312		5/23 (22%)
		leucine-rich repeat	292..315	CDD:275380	4/22 (18%)
		LRR 11	315..337		9/21 (43%)
		leucine-rich repeat	316..338	CDD:275380	9/21 (43%)
		LRR 12	340..361		4/20 (20%)
		leucine-rich repeat	341..364	CDD:275380	4/22 (18%)
		LRR 13	364..385		7/20 (35%)
		leucine-rich repeat	365..388	CDD:275380	8/22 (36%)
		LRR 14	388..409		6/28 (21%)
		leucine-rich repeat	389..410	CDD:275380	6/28 (21%)
		PCC	394..>458	CDD:188093	14/92 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	474..499