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Protein Alignment Gp150 and lron-15

DIOPT Version :10

Sequence 1:	NP_477049.2	Gene:	Gp150 / 37549	FlyBaseID:	FBgn0013272	Length:	1076	Species:	Drosophila melanogaster
Sequence 2:	NP_495322.3	Gene:	lron-15 / 174079	WormBaseID:	WBGene00016974	Length:	1275	Species:	Caenorhabditis elegans

Alignment Length:	673	Identity:	146/673 - (21%)
Similarity:	280/673 - (41%)	Gaps:	142/673 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   274 ATCSRLDMGIQKFGSDITDLVVTNVGPKYPIL------------MGPNFFQNLGLKNVASIKIAN 326
            :|..||::.    |:.|.::....:....|:|            :.|..|:.  |||:.|:.:.|
Worm   461 STVRRLNLA----GNRINNMSDYLIFEHMPLLTYVDVSFNRIRFISPRVFEK--LKNLESLFLQN 519

  Fly   327 CTLEYLHAEAFHGLNELYAVNLTDVGLAIINPDTFVGNKKLRMLTISGNDLSVM----------- 380
            ..|  .|..:...|::|..:.|.:..:..|:..:.....||:.|:::||.|.::
Worm   520 NQL--AHFPSLFRLDKLRHLMLDNNQIQKIDNFSLADLPKLQHLSLAGNQLDIITENMFGSSSSS 582

  Fly   381 ---------SSIHYLLKSS-----SIEELDFSRNNLMELNPKAFSHLSNVVYINLSQNSLKKLPE 431
                     :.||.:...|     ::::|..|.||:..:....||:|.|:.|::||.|.:.|:..
Worm   583 ELKSLNLAHNKIHSISSRSFSDLDNLQQLRLSHNNIRTITSMTFSNLRNLRYLDLSHNRIIKILP 647

  Fly   432 KAFEKVTLLEELDLSYNSLTELPRDIFNG-TTLSILHLKYNTFNG-------------------- 475
            .|..::..|:.|.|.:|:|.|:.||.|.. :.|..|.|.:|.|..
Worm   648 SALYQLPALDVLHLDHNNLNEIDRDAFRSFSDLQSLKLSHNAFRRFSCEFLGSISQVHQLDLSSN 712

  Fly   476 -----DLHFGTKDLQQLDLSFNSIVQVHHSMFDKMPGLTNLNLKGNGIKKIQPDSFLTLKNLRHI 535
                 |:....:.:::|.|:.||:.:::..:......||::::..|||..:..|:|...:.|.||
Worm   713 QINEIDIFCIARGIRKLSLASNSVEKINRKLLQDATELTSIDISHNGIIDVDSDAFCECRKLSHI 777

  Fly   536 ------------------------DLSINDLDQISGMLFFKNSELDVIRLNDNPRLSQLPTDGFL 576
                                    |:|.||:..:....|.||:.|. :.:|:| :||::|.:...
Worm   778 KLSHNYIRNLWKGTFQYQESLHTLDISFNDILFLHQGTFGKNNILQ-LHVNNN-KLSRIPLEALS 840

  Fly   577 SYSGEFTVYYLDISNCAIGPLGHKAFSTMPHLTTLKLAWNNINHLPREIFTGLHKLIDLDLSNNL 641
            |...  :::.||:::..|..:.....::..:|:.|..|.|.::.:....|..|..|..||||||.
Worm   841 STMA--SLHLLDLAHNNIKIVDSSQLTSFGNLSILSFANNKVDSIEDGAFENLLSLKILDLSNNP 903

  Fly   642 ITRMDDLIFMD----------------------NGELTKLSLAGNPISRLSVRLFLPLHQLRCLD 684
            :|......|.|                      :..:..|:::.|.|..||.:...||.::..||
Worm   904 VTSWSPTAFRDLSHSISSINMANTGLFSMPKFSHRSIQSLNISCNKIYELSEKDLAPLTKVVALD 968

  Fly   685 VNDCELTTLLSDRDLGAGYKIFDSLRSFNASGNLIKKISSEDVKSFKNLRSLDITNNP-LKCTPD 748
            ::...|..:.|     ..::....|:..|.|.|.|..:::|.::....|.:|.:::.| |...||
Worm   969 ISHNNLKQISS-----MAFEPLIHLKQLNVSANPITHLTNEHIQQLYKLETLHVSDMPFLLRLPD 1028

  Fly   749 FQEFISYVTLQMQMTPKRLPVLANLEDDATIVQLETLAQAGWSSL--AHEVCKHAEGSDLLDEKK 811
            ...|       .||...:...|.|:.|.|...|:.::.    |:|  .|.:....:.|.|  :::
Worm  1029 SHAF-------GQMNNLKHFFLYNIPDMARPYQISSIL----SNLPPLHTIYVDIKESAL--DRQ 1080

  Fly   812 ADSAEAKLEKRLKESVKKLNEDE 834
            ..:|:.:|.:.|..:.:.|.:.|
Worm  1081 FYTADTRLLRHLVVAGRNLTKIE 1103

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.