DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gp150 and si:dkey-182i3.11

DIOPT Version :9

Sequence 1:NP_477049.2 Gene:Gp150 / 37549 FlyBaseID:FBgn0013272 Length:1076 Species:Drosophila melanogaster
Sequence 2:XP_021322095.1 Gene:si:dkey-182i3.11 / 100334238 ZFINID:ZDB-GENE-121214-258 Length:710 Species:Danio rerio


Alignment Length:534 Identity:138/534 - (25%)
Similarity:224/534 - (41%) Gaps:144/534 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   302 YPILMGPNFFQNLGLKN--VASIKI---ANCTLEYLHAEAFHGLNELYAV-----------NLTD 350
            |.:|.||....:|.|::  :..|::   .|||  || |:.:...|:|.:|           |..|
Zfish   192 YGVLEGPLALTDLQLRDNMIDMIEMNVFENCT--YL-AKLYLSKNKLKSVGNGSFKGATGLNHLD 253

  Fly   351 VGL-------AIINPDTFVGNKKLRMLTISGNDL-----SVMSSIHYLLKSSSIEELDFSRNNLM 403
            :||       .|:..:|    ..|..|.:..||:     :|.|.|      .|::.||.|.|.|:
Zfish   254 LGLNGLAGIPTIVLQET----SNLTSLYLQKNDITSIPDNVFSEI------LSLKHLDLSYNGLV 308

  Fly   404 ELNPKAFSHLSNVVYINLSQNSLKKLPEKAFEKVTLLEELDLSYNSLTELPRDIFNGTTLSILHL 468
            .::..:|..||.:||::||.|.|:.|.:..||.:..||.|:|.:|.||.||.::|...|:     
Zfish   309 SISNGSFRSLSQLVYLDLSFNQLQTLTQHVFEDLGKLENLNLYHNKLTSLPNNMFKNLTM----- 368

  Fly   469 KYNTFNGDLHFGTKDLQQLDLSFNSIVQVHHSMFDKMPGLTNLNLKGNGIKKIQPDSFLTLKNLR 533
                           |::|.|..|:|..:...:|..:..|.:|.|..|.|.|:...:|..|:.|:
Zfish   369 ---------------LKELQLDSNNISVIPPDLFHPLSALKDLQLDNNHISKLHSHTFKKLRQLK 418

  Fly   534 HIDLSINDLDQISGMLFFKNSELDVIRLNDNPRLSQLPTDGFLSYSGEFTVYYLDISNCAIGPLG 598
            .:|:|.|||.:|...||.||  |..:.|.:|          .:|:..:|                
Zfish   419 QLDISSNDLTKIPNHLFHKN--LKELNLENN----------HISFISKF---------------- 455

  Fly   599 HKAFSTMPHLTTLKLAWNNINHLPREIFTGLHKLIDLDLSNNLITRMDDLIFMDNGELTKLSLAG 663
              :|..:..|.:|||:.||::.|.||:.|.|             ||:.:|:           |..
Zfish   456 --SFKNLHRLQSLKLSHNNLSKLYRELLTNL-------------TRLRELL-----------LNE 494

  Fly   664 NPISRLSVRLFLPLHQLRCLDVNDCELTTLLSD--RDLGAGYKIFDSLRSFNASGNLIKKISSED 726
            |.|..:.|..|..|..||.||:::.::..:|.|  .||.|       |:..:.|.|.:..:..:.
Zfish   495 NQIETIPVGFFKGLENLRVLDLSNNKMHFILPDAFNDLSA-------LKDLDLSFNFLHNLPEDI 552

  Fly   727 VKSFKNLRSLDITNNPLKCTPD--FQEFISYVTLQM------QMTPKRLPVLANLE--------- 774
            ..|.:||..|.:.||.|:..|.  |...:....|.:      ::.|.:...|..|.         
Zfish   553 FASLRNLTKLHLQNNKLRYLPSRLFSALVGLEELHLDRNYIQRIHPTQFEGLVKLHELDMKSNQL 617

  Fly   775 ---DDATIVQLETL 785
               :|.|::.|..|
Zfish   618 RSMEDGTLMPLRKL 631

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gp150NP_477049.2 LRR_8 317..377 CDD:290566 19/82 (23%)
leucine-rich repeat 343..366 CDD:275380 8/40 (20%)
leucine-rich repeat 367..391 CDD:275380 7/28 (25%)
LRR_RI <374..619 CDD:238064 71/249 (29%)
LRR_8 390..450 CDD:290566 23/59 (39%)
leucine-rich repeat 393..415 CDD:275380 7/21 (33%)
leucine-rich repeat 416..439 CDD:275380 9/22 (41%)
leucine-rich repeat 440..483 CDD:275380 11/42 (26%)
leucine-rich repeat 463..481 CDD:275380 0/17 (0%)
LRR_8 484..542 CDD:290566 18/57 (32%)
leucine-rich repeat 484..507 CDD:275380 6/22 (27%)
leucine-rich repeat 508..531 CDD:275380 8/22 (36%)
leucine-rich repeat 532..569 CDD:275380 14/36 (39%)
leucine-rich repeat 556..583 CDD:275380 4/26 (15%)
leucine-rich repeat 570..607 CDD:275380 3/36 (8%)
LRR_RI <586..745 CDD:238064 40/160 (25%)
LRR_8 606..666 CDD:290566 16/59 (27%)
leucine-rich repeat 608..631 CDD:275380 11/22 (50%)
leucine-rich repeat 632..655 CDD:275380 3/22 (14%)
leucine-rich repeat 656..674 CDD:275380 4/17 (24%)
leucine-rich repeat 733..745 CDD:275378 5/11 (45%)
si:dkey-182i3.11XP_021322095.1 PLN00113 97..>617 CDD:331614 134/518 (26%)
leucine-rich repeat 129..152 CDD:275380
leucine-rich repeat 153..176 CDD:275380
leucine-rich repeat 177..200 CDD:275380 4/7 (57%)
leucine-rich repeat 201..224 CDD:275380 6/24 (25%)
leucine-rich repeat 225..248 CDD:275380 5/23 (22%)
leucine-rich repeat 249..272 CDD:275380 6/26 (23%)
leucine-rich repeat 273..296 CDD:275380 7/28 (25%)
leucine-rich repeat 297..320 CDD:275380 7/22 (32%)
leucine-rich repeat 321..344 CDD:275380 9/22 (41%)
leucine-rich repeat 345..368 CDD:275380 10/22 (45%)
leucine-rich repeat 369..392 CDD:275380 6/22 (27%)
leucine-rich repeat 393..438 CDD:275380 17/44 (39%)
leucine-rich repeat 417..436 CDD:275380 8/18 (44%)
leucine-rich repeat 439..462 CDD:275380 6/50 (12%)
leucine-rich repeat 463..486 CDD:275380 11/35 (31%)
leucine-rich repeat 487..510 CDD:275380 7/33 (21%)
leucine-rich repeat 511..534 CDD:275380 8/22 (36%)
leucine-rich repeat 535..558 CDD:275380 4/22 (18%)
leucine-rich repeat 559..582 CDD:275380 7/22 (32%)
leucine-rich repeat 583..606 CDD:275380 3/22 (14%)
leucine-rich repeat 607..628 CDD:275380 3/20 (15%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
33.010

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