DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment wdp and lrrc4.2

DIOPT Version :9

Sequence 1:NP_001286712.1 Gene:wdp / 37548 FlyBaseID:FBgn0034718 Length:677 Species:Drosophila melanogaster
Sequence 2:NP_001093494.1 Gene:lrrc4.2 / 566572 ZFINID:ZDB-GENE-030131-7997 Length:644 Species:Danio rerio


Alignment Length:493 Identity:99/493 - (20%)
Similarity:153/493 - (31%) Gaps:200/493 - (40%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 VHLTAWLALFLIVV--------ANATPTPARTPTGCPADCTCS---------------------- 38
            || .||.|..|..|        .:|.|:...|   ||:.|.||                      
Zfish     9 VH-RAWNAALLCAVYLMVRSWSVSAAPSGQLT---CPSVCFCSNVSNKVVCTRRSLVRVPPGIPA 69

  Fly    39 LSQH--------------THKPLYHLKC-----NSTRGLRLTEKTFQSTVPVHSIDLSHLNLTRL 84
            .::|              |.:.|.||:.     ||.|.:.:  ..|.....:::::|....||.:
Zfish    70 TTRHLNLMENSIETIEAGTFQHLRHLEVLQLGRNSIRQIEV--GAFSGLNSLNTLELFDNRLTVI 132

  Fly    85 -------------------------SHLLDKLPELTSADLSHNQLKDLGHLGKG-LKRL-NLKHN 122
                                     |:..:::|.|...||  .:|:.|.::.:| .:.| |||:.
Zfish   133 PSGAFEYLSKLRELWLRSNPIESIPSYAFNRVPSLMRLDL--GELRKLEYISEGAFEGLHNLKYL 195

  Fly   123 QLTSDKLRKLP--------QHLQV----------------------------------------- 138
            .|....||::|        :.|::                                         
Zfish   196 NLGMCNLREMPVLTPLVGLEELEMSENYFPELKPGSFRGLKSLKKLWIMNSRITTIERNAFDDVT 260

  Fly   139 ----LNLQHNNITHLPLEL-THMHQLHQLELSHNAINCSCQTLEVRNWLVERIVYMEHPV----- 193
                |||.|||::.||.:| ..:..|.:|.|.||...|.|..:.:..||.|.|     |.     
Zfish   261 ALVELNLAHNNLSSLPHDLFAPLSYLVELHLHHNPWRCDCDVVWLAWWLREYI-----PTNSTCC 320

  Fly   194 -VCSYPLEFRGRSWLQLKQDEICKKEKYQWFDTEENELMMGDQPAAVSAEREDEEELGKDFLP-- 255
             .|..|...|||..:::.|..         |......::...:...:||||  ..||.....|  
Zfish   321 GRCHTPAYLRGRYLVEVDQST---------FQCSAPFILDAPRDLNISAER--VAELKCRTAPMS 374

  Fly   256 ----IVGNPAATAKKVRSPQIP------------LPSD-------------QVEGSGDLSETNME 291
                ::.|..........|:|.            ||:|             ....|..|:.|..|
Zfish   375 SVRWLLPNGTVLTHGSNHPRISVLNDGTLNFSNVLPADTGVYTCMVTNMAGNSNASAYLNVTAAE 439

  Fly   292 LK------LPEETVAEPEAAESQLV---DAAASPSVLE 320
            |.      ....||.|.|....:::   ...|||||.:
Zfish   440 LNTSNLSYFTTVTVEEVEPTSQEVIKPKTVTASPSVFQ 477

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdpNP_001286712.1 LRR_RI <31..176 CDD:238064 50/266 (19%)
leucine-rich repeat 47..70 CDD:275378 7/27 (26%)
LRR_8 71..124 CDD:290566 15/79 (19%)
leucine-rich repeat 73..93 CDD:275378 4/44 (9%)
leucine-rich repeat 94..112 CDD:275378 5/17 (29%)
LRR_8 112..169 CDD:290566 24/112 (21%)
leucine-rich repeat 114..134 CDD:275378 8/28 (29%)
leucine-rich repeat 136..158 CDD:275378 10/67 (15%)
leucine-rich repeat 159..171 CDD:275378 5/11 (45%)
lrrc4.2NP_001093494.1 leucine-rich repeat 71..94 CDD:275380 3/22 (14%)
LRR_8 72..129 CDD:290566 10/58 (17%)
LRR_RI 74..>276 CDD:238064 34/205 (17%)
leucine-rich repeat 95..118 CDD:275380 5/24 (21%)
leucine-rich repeat 119..142 CDD:275380 3/22 (14%)
LRR_8 141..202 CDD:290566 13/62 (21%)
leucine-rich repeat 143..166 CDD:275380 1/22 (5%)
leucine-rich repeat 167..191 CDD:275380 7/25 (28%)
leucine-rich repeat 192..213 CDD:275380 6/20 (30%)
LRR_8 213..272 CDD:290566 6/58 (10%)
leucine-rich repeat 214..237 CDD:275380 1/22 (5%)
leucine-rich repeat 238..261 CDD:275380 0/22 (0%)
leucine-rich repeat 262..283 CDD:275380 9/20 (45%)
LRRCT 294..345 CDD:214507 15/64 (23%)
IG_like 353..435 CDD:214653 15/83 (18%)
Ig 365..435 CDD:299845 11/69 (16%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24369
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.100

Return to query results.
Submit another query.