Protein Alignment wdp and slit1a

DIOPT Version :10

• Sequence 1: NP_611661.1
• Gene: wdp / 37548
• FlyBaseID: FBgn0034718
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001030140.1
• Gene: slit1a / 556123
• ZFINID: ZDB-GENE-030722-3
• Length: 1524
• Species: Danio rerio
• Alignment Length: 363
• Identity: 79/363 - (21%)
• Similarity: 129/363 - (35%)
• Gaps: 125/363 - (34%)

  Fly     4 VHLTAWLALFLIVVANATPTPARTPTGCPADCTCSLSQHTHKPLYHLKCNSTRGLRLTEKTFQST 68
            :.:..|:.|.:          .:|.:||||.||||.:.        :.|:   ||.|  |.....
Zfish    10 LEVCVWVLLLV----------CKTGSGCPALCTCSGTT--------VDCH---GLGL--KNIPRN 51

  Fly    69 VP--VHSIDLSHLNLTRLSH-------------------------LLDKLPELTSADLSHNQLKD 106
            :|  ...::|:..||||::.                         ..|::.||....|:.|||..
Zfish    52 IPRNTERLELNGNNLTRINRNDFTGLKYLRVLQLMENQIVTVERGAFDEMRELERLRLNRNQLHQ 116

  Fly   107 LGHL----GKGLKRLNLKHN-------------------QLTSDKLR-------KLPQHLQVLNL 141
            |..|    ...|.||:|..|                   ||..:.:.       :..:.|:||.|
Zfish   117 LPELLFQKNAALSRLDLSENFIQAIPRKAFRGATDIKNLQLDKNHISCIEDGAFRAMRGLEVLTL 181

  Fly   142 QHNNITHLPL-ELTHMHQLHQLELSHNAINCSCQTLEVRNWLVERIVYMEHPVV-----CSYPLE 200
            .:|||:.:|: ...||.:|....|..|.:.|.|....:..||.||      |.:     ||.|..
Zfish   182 NNNNISSIPVSSFNHMPKLRTFRLHSNNLVCDCVLSWLSQWLRER------PNIGLFTQCSSPAP 240

  Fly   201 FRGRSWLQLKQDEI-CKKEKYQWFDT---EENELMMGDQPAAVSAEREDEEELGKDFLPIVGNPA 261
            .||.:..::::.|. |..:.    |:   :...|..|..||..|......:..||
Zfish   241 LRGLNVAEVQKHEFSCSGQS----DSAVGQSCSLSSGSCPAVCSCNNNIVDCRGK---------- 291

  Fly   262 ATAKKVRSPQIPLPSDQVEGSGDLSETNMELKLPEETV 299
                   .|.: :||       .|.::..|::|.:.::
Zfish   292 -------GPTL-IPS-------SLPDSMTEIRLEQNSI 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wdp	NP_611661.1	leucine-rich repeat	47..70	CDD:275378	5/22 (23%)
		LRR	<72..>169	CDD:443914	34/152 (22%)
		leucine-rich repeat	73..93	CDD:275378	6/44 (14%)
		leucine-rich repeat	94..112	CDD:275378	7/21 (33%)
		leucine-rich repeat	114..134	CDD:275378	7/45 (16%)
		leucine-rich repeat	136..158	CDD:275378	10/22 (45%)
		leucine-rich repeat	159..171	CDD:275378	3/11 (27%)
slit1a	NP_001030140.1	LRR	<25..>245	CDD:443914	60/238 (25%)
		leucine-rich repeat	36..55	CDD:275380	6/31 (19%)
		leucine-rich repeat	56..79	CDD:275380	5/22 (23%)
		leucine-rich repeat	80..103	CDD:275380	1/22 (5%)
		leucine-rich repeat	104..127	CDD:275380	7/22 (32%)
		leucine-rich repeat	128..151	CDD:275380	5/22 (23%)
		leucine-rich repeat	152..175	CDD:275380	2/22 (9%)
		leucine-rich repeat	176..199	CDD:275380	10/22 (45%)
		leucine-rich repeat	200..327	CDD:275380	31/150 (21%)
		LRR	<282..>454	CDD:443914	8/58 (14%)
		leucine-rich repeat	328..351	CDD:275380
		leucine-rich repeat	352..372	CDD:275380
		leucine-rich repeat	400..423	CDD:275380
		leucine-rich repeat	424..521	CDD:275380
		LRR	515..>813	CDD:443914
		leucine-rich repeat	522..559	CDD:275380
		leucine-rich repeat	560..583	CDD:275380
		leucine-rich repeat	584..607	CDD:275380
		leucine-rich repeat	608..631	CDD:275380
		leucine-rich repeat	632..653	CDD:275380
		leucine-rich repeat	656..747	CDD:275380
		leucine-rich repeat	748..778	CDD:275380
		leucine-rich repeat	779..802	CDD:275380
		leucine-rich repeat	803..823	CDD:275380
		leucine-rich repeat	827..850	CDD:275380
		PCC	835..>907	CDD:188093
		EGF_CA	920..955	CDD:238011
		EGF_CA	958..996	CDD:238011
		EGF_CA	998..1034	CDD:238011
		EGF_CA	1078..1112	CDD:238011
		LamG	1179..1312	CDD:214598