DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment wdp and chp

DIOPT Version :9

Sequence 1:	NP_001286712.1	Gene:	wdp / 37548	FlyBaseID:	FBgn0034718	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_001263137.1	Gene:	chp / 43690	FlyBaseID:	FBgn0267435	Length:	1338	Species:	Drosophila melanogaster

Alignment Length:	320	Identity:	72/320 - (22%)
Similarity:	119/320 - (37%)	Gaps:	110/320 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 NSTRGLRLTE----KTFQSTVPVHSIDLSHLNLTRLSHLLD---------------KLPELTSAD 98
            :|...|.|.|    ..|.||  :||:|||  |..|....||               .:|:|...|
  Fly   845 SSLAALTLCELHLSNNFIST--IHSMDLS--NKFRSLRYLDISYNYLLRIDDAVFATMPKLAVLD 905

  Fly    99 LSHN---QLKDLGHLG-----------------------KGLKRLNLKHNQLTSDKLRKLPQ--- 134
            ||||   ::.|...:|                       |.|:...|.:|:|.|     :||
  Fly   906 LSHNRDLKVMDKSFMGLENSLIKLGLENISLSTVPEIRLKYLREFRLGYNELPS-----IPQELA 965

  Fly   135 ----HLQVLNLQHNNITHLPLELTHMHQLHQLELSHN-----------AINCSCQTLEVRNWLVE 184
                :|::|:|.:|::|::||....:..|.:|.||.|           .:|...:.|::.|:
  Fly   966 HNMSNLRMLDLSNNDLTNVPLMTQALPHLRRLMLSGNPITSLNNNSFDGVNEDLEMLDISNF--- 1027

  Fly   185 RIVYMEHPVVCSYP----LEFRGRSWLQLKQDEICKKEKYQ----WFDTEENELMMGDQPAAVSA 241
            |:.|.|:..:.|.|    |:....|.|:........:..|.    |.:        ..||
  Fly  1028 RLHYFEYGCLDSLPHLRSLKLTAYSHLEHFNIPHLLRHHYNIRQLWIE--------APQP----- 1079

  Fly   242 EREDEEELGKDFLPIVGNPAATAKKVRSPQIPLPSD---QVEGSGDLSETNMELKLPEET 298
                       |..||...:...:::::.|:..|:|   ::||......||:....|:.|
  Fly  1080 -----------FTRIVKKGSGPTQEMQTLQLGNPTDLQREMEGHLPSKLTNITFSGPQFT 1128

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
wdp	NP_001286712.1	LRR_RI	<31..176	CDD:238064	46/185 (25%)
		leucine-rich repeat	47..70	CDD:275378	7/20 (35%)
		LRR_8	71..124	CDD:290566	22/93 (24%)
		leucine-rich repeat	73..93	CDD:275378	8/34 (24%)
		leucine-rich repeat	94..112	CDD:275378	8/43 (19%)
		LRR_8	112..169	CDD:290566	20/74 (27%)
		leucine-rich repeat	114..134	CDD:275378	5/19 (26%)
		leucine-rich repeat	136..158	CDD:275378	7/21 (33%)
		leucine-rich repeat	159..171	CDD:275378	5/22 (23%)
chp	NP_001263137.1	leucine-rich repeat	84..103	CDD:275380
		LRR_8	102..163	CDD:290566
		leucine-rich repeat	104..128	CDD:275380
		LRR_RI	<128..261	CDD:238064
		leucine-rich repeat	129..152	CDD:275380
		LRR_8	152..212	CDD:290566
		leucine-rich repeat	153..177	CDD:275380
		leucine-rich repeat	178..201	CDD:275380
		LRR_8	202..261	CDD:290566
		leucine-rich repeat	202..226	CDD:275380
		leucine-rich repeat	227..250	CDD:275380
		leucine-rich repeat	251..279	CDD:275380
		leucine-rich repeat	280..326	CDD:275380
		LRR_8	326..386	CDD:290566
		leucine-rich repeat	327..348	CDD:275380
		leucine-rich repeat	352..375	CDD:275380
		leucine-rich repeat	376..401	CDD:275380
		leucine-rich repeat	426..450	CDD:275378
		LRR_RI	<448..651	CDD:238064
		leucine-rich repeat	451..474	CDD:275380
		LRR_8	473..559	CDD:290566
		leucine-rich repeat	475..524	CDD:275380
		leucine-rich repeat	500..519	CDD:275380
		leucine-rich repeat	525..548	CDD:275380
		leucine-rich repeat	549..574	CDD:275380
		LRR_8	573..633	CDD:290566
		leucine-rich repeat	575..598	CDD:275380
		leucine-rich repeat	599..622	CDD:275380
		LRR_8	622..683	CDD:290566
		leucine-rich repeat	623..646	CDD:275380
		leucine-rich repeat	647..730	CDD:275380
		leucine-rich repeat	648..673	CDD:275380
		leucine-rich repeat	674..705	CDD:275380
		LRR_8	704..763	CDD:290566
		leucine-rich repeat	731..754	CDD:275380
		LRR_8	753..813	CDD:290566
		leucine-rich repeat	755..778	CDD:275380
		leucine-rich repeat	779..802	CDD:275380
		leucine-rich repeat	803..823	CDD:275380
		leucine-rich repeat	852..876	CDD:275380	11/27 (41%)
		LRR_8	854..910	CDD:290566	19/59 (32%)
		LRR_RI	<877..>1006	CDD:238064	31/133 (23%)
		leucine-rich repeat	877..900	CDD:275380	2/22 (9%)
		leucine-rich repeat	901..925	CDD:275380	8/23 (35%)
		leucine-rich repeat	926..946	CDD:275380	0/19 (0%)
		LRR_8	947..1004	CDD:290566	19/61 (31%)
		leucine-rich repeat	947..970	CDD:275380	7/27 (26%)
		leucine-rich repeat	971..993	CDD:275380	7/21 (33%)
		LRR_8	992..1049	CDD:290566	14/59 (24%)
		leucine-rich repeat	994..1014	CDD:275380	5/19 (26%)
		leucine-rich repeat	1019..1042	CDD:275380	6/25 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24369
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100