DRSC/TRiP Functional Genomics Resources

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Protein Alignment wdp and Lrrc4

DIOPT Version :9

Sequence 1:NP_001286712.1 Gene:wdp / 37548 FlyBaseID:FBgn0034718 Length:677 Species:Drosophila melanogaster
Sequence 2:NP_619623.2 Gene:Lrrc4 / 192198 MGIID:2182081 Length:652 Species:Mus musculus


Alignment Length:472 Identity:92/472 - (19%)
Similarity:149/472 - (31%) Gaps:198/472 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 VHLTAWLALFLIVVANATPTPARTPTGCPADCTCS------------------------------ 38
            |:|||.:.:....:|.|.   :..|..||:.|:||                              
Mouse    21 VYLTAQVWILCAAIAAAA---SAGPQNCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTRYLNLM 82

  Fly    39 ------LSQHTHKPLYHLKC-----NSTRGLRLTEKTFQSTVPVHSIDLSHLNLTRL-------- 84
                  :...|.:.|:||:.     ||.|.:.:  ..|.....:::::|....||.:        
Mouse    83 ENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEV--GAFNGLASLNTLELFDNWLTVIPSGAFEYL 145

  Fly    85 -----------------SHLLDKLPELTSADLSHNQLKDLGHLGKGLKR--LNLKHNQLTSDKLR 130
                             |:..:::|.|...||  .:||.|.::.:|...  .|||:..|....::
Mouse   146 SKLRELWLRNNPIESIPSYAFNRVPSLMRLDL--GELKKLEYISEGAFEGLFNLKYLNLGMCNIK 208

  Fly   131 KLP--------QHLQV---------------------------------------------LNLQ 142
            .:|        :.|::                                             |||.
Mouse   209 DMPNLTPLVGLEELEMSGNHFPEIRPGSFHGLSSLKKLWVMNSQVSLIERNAFDGLASLVELNLA 273

  Fly   143 HNNITHLPLEL-THMHQLHQLELSHNAINCSCQTLEVRNWLVERIVYMEHPV------VCSYPLE 200
            |||::.||.:| |.:..|.:|.|.||..||.|..|.:..||.|.|     |.      .|..|:.
Mouse   274 HNNLSSLPHDLFTPLRYLVELHLHHNPWNCDCDILWLAWWLREYI-----PTNSTCCGRCHAPMH 333

  Fly   201 FRGRSWLQLKQDEICKKEKYQWFDTEENELMMGDQPAAVSAEREDEEELG---------KDFLPI 256
            .|||..:::.|..         |......:|  |.|..::...:...||.         |..|| 
Mouse   334 MRGRYLVEVDQAA---------FQCSAPFIM--DAPRDLNISEDRMAELKCRTPPMSSVKWLLP- 386

  Fly   257 VGNPAATAKKVRSPQIPLPSD---------------------QVEGSGD----LSETNMELKLP- 295
              |....:...|.|:|.:.:|                     .|.|:.:    |:.::.||..| 
Mouse   387 --NGTVLSHASRHPRISVLNDGTLNFSRVLLIDTGVYTCMVTNVAGNSNASAYLNVSSAELNTPN 449

  Fly   296 ---------EETVAEPE 303
                     |.|...||
Mouse   450 FSFFTTVTVETTEISPE 466

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdpNP_001286712.1 LRR_RI <31..176 CDD:238064 49/266 (18%)
leucine-rich repeat 47..70 CDD:275378 7/27 (26%)
LRR_8 71..124 CDD:290566 15/79 (19%)
leucine-rich repeat 73..93 CDD:275378 4/44 (9%)
leucine-rich repeat 94..112 CDD:275378 6/17 (35%)
LRR_8 112..169 CDD:290566 22/112 (20%)
leucine-rich repeat 114..134 CDD:275378 5/29 (17%)
leucine-rich repeat 136..158 CDD:275378 11/67 (16%)
leucine-rich repeat 159..171 CDD:275378 5/11 (45%)
Lrrc4NP_619623.2 LRRNT 45..78 CDD:214470 5/32 (16%)
LRR_8 74..132 CDD:290566 9/59 (15%)
LRR 1 75..96 1/20 (5%)
leucine-rich repeat 76..99 CDD:275380 2/22 (9%)
LRR_RI 91..304 CDD:238064 42/216 (19%)
LRR 2 99..120 6/22 (27%)
leucine-rich repeat 100..123 CDD:275380 5/24 (21%)
LRR 3 123..144 3/20 (15%)
leucine-rich repeat 124..147 CDD:275380 3/22 (14%)
LRR_8 146..207 CDD:290566 13/62 (21%)
LRR 4 147..168 1/20 (5%)
leucine-rich repeat 148..171 CDD:275380 1/22 (5%)
LRR 5 171..193 7/23 (30%)
leucine-rich repeat 172..196 CDD:275380 7/25 (28%)
LRR 6 196..217 5/20 (25%)
leucine-rich repeat 197..218 CDD:275380 4/20 (20%)
LRR_8 218..277 CDD:290566 6/58 (10%)
LRR 7 218..239 1/20 (5%)
leucine-rich repeat 219..242 CDD:275380 1/22 (5%)
LRR 8 242..263 0/20 (0%)
leucine-rich repeat 243..266 CDD:275380 0/22 (0%)
LRR 9 266..287 9/20 (45%)
leucine-rich repeat 267..288 CDD:275380 10/20 (50%)
LRRCT 299..350 CDD:214507 17/64 (27%)
IG_like 358..440 CDD:214653 14/84 (17%)
Ig 369..440 CDD:299845 13/73 (18%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24369
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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