Protein Alignment wdp and slt-1

DIOPT Version :10

• Sequence 1: NP_611661.1
• Gene: wdp / 37548
• FlyBaseID: FBgn0034718
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_510437.2
• Gene: slt-1 / 181562
• WormBaseID: WBGene00004854
• Length: 1410
• Species: Caenorhabditis elegans
• Alignment Length: 356
• Identity: 79/356 - (22%)
• Similarity: 137/356 - (38%)
• Gaps: 99/356 - (27%)

  Fly    14 LIVVANATPTPARTPTGCPADCTC-------------SLSQHTHKPLYHLKCNSTRGLRLTEKTF 65
            |::..:||         |||:|.|             .:.|:.......|........::....|
 Worm     9 LLIPESAT---------CPAECVCVDRTVSCVGQQLTEVPQNIPNDTIRLDLQDNEITKIGPNDF 64

  Fly    66 QS-------------TVPVHSIDLS--------HLNLTRLSHLLDKLPELTSADLSHNQLKDLGH 109
            .|             .|.:|:...|        .|:..|:.||.|        ::..|.||
 Worm    65 SSLMNLKALQLMDNQIVTIHNQSFSSLVFLQKLRLSRNRIRHLPD--------NVFQNNLK---- 117

  Fly   110 LGKGLKRLNLKHNQLT--SDKLRKLPQHLQVLNLQHNNI---------THLPLELTHMH------ 157
                |..|:|..|.:|  ||...:.|:.|:||||..|:|         :.:.||:..::
 Worm   118 ----LTHLDLSENDITVVSDAQLQGPEFLEVLNLDKNHIFCLENNVISSWVSLEVLTLNGNRLTT 178

  Fly   158 -------QLHQLELSHNAINCSCQTLEVRNWLVERIVYMEHPVVCSYPLEFRGRSWLQLKQDEI- 214
                   :..||:|.:|..||.|:...:|.||.:  ...::..||:.||..:|.| :::.||:.
 Worm   179 FEEPSNARFRQLDLFNNPWNCDCRLRWMRKWLEK--AEGQNKTVCATPLNLQGSS-IEILQDKFM 240

  Fly   215 -C---KKEKY-QWFDTEENELMMGDQPAAVSAEREDEEELGKDFLPIVGNPAATAKKVRSPQI-P 273
             |   :|.:| :..:|.|    :...|...:....|..:.|..::|....|:.|..::...|| .
 Worm   241 TCSGNRKRRYKKTCETAE----ICPLPCTCTGTTVDCRDSGLTYVPTNLPPSTTEIRLEQNQISS 301

  Fly   274 LPSDQVEGSGDLSETNMELKLPEETVAEPEA 304
            :||...:...:|  |.::|.....|..:|:|
 Worm   302 IPSHSFKNLKNL--TRLDLSKNIITEIQPKA 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wdp	NP_611661.1	leucine-rich repeat	47..70	CDD:275378	3/35 (9%)
		LRR	<72..>169	CDD:443914	31/128 (24%)
		leucine-rich repeat	73..93	CDD:275378	6/27 (22%)
		leucine-rich repeat	94..112	CDD:275378	3/17 (18%)
		leucine-rich repeat	114..134	CDD:275378	7/21 (33%)
		leucine-rich repeat	136..158	CDD:275378	9/43 (21%)
		leucine-rich repeat	159..171	CDD:275378	4/11 (36%)
slt-1	NP_510437.2	LRRNT	17..47	CDD:214470	6/29 (21%)
		leucine-rich repeat	26..45	CDD:275380	1/18 (6%)
		LRR	46..420	CDD:443914	70/310 (23%)
		leucine-rich repeat	48..69	CDD:275380	3/20 (15%)
		leucine-rich repeat	70..93	CDD:275380	3/22 (14%)
		leucine-rich repeat	94..117	CDD:275380	6/30 (20%)
		leucine-rich repeat	118..165	CDD:275380	15/46 (33%)
		leucine-rich repeat	142..163	CDD:275380	7/20 (35%)
		leucine-rich repeat	166..284	CDD:275380	29/124 (23%)
		leucine-rich repeat	285..312	CDD:275380	6/26 (23%)
		leucine-rich repeat	313..336	CDD:275380	6/20 (30%)
		leucine-rich repeat	337..384	CDD:275380
		leucine-rich repeat	385..408	CDD:275380
		PCC	390..>478	CDD:188093
		LRRNT	484..512	CDD:214470
		leucine-rich repeat	494..516	CDD:275380
		leucine-rich repeat	517..538	CDD:275380
		LRR	<523..>812	CDD:443914
		leucine-rich repeat	539..562	CDD:275380
		leucine-rich repeat	563..586	CDD:275380
		leucine-rich repeat	587..610	CDD:275380
		leucine-rich repeat	611..675	CDD:275380
		leucine-rich repeat	676..729	CDD:275380
		leucine-rich repeat	730..753	CDD:275380
		leucine-rich repeat	754..777	CDD:275380
		leucine-rich repeat	778..799	CDD:275380
		PCC	783..>924	CDD:188093
		EGF_CA	909..945	CDD:238011
		EGF_CA	947..983	CDD:238011
		EGF_CA	<994..1023	CDD:238011
		EGF_CA	1025..1061	CDD:238011
		LamG	1133..1268	CDD:214598
		CT	1334..1405	CDD:214482