DRSC/TRiP Functional Genomics Resources

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Protein Alignment wdp and SLITRK4

DIOPT Version :9

Sequence 1:NP_001286712.1 Gene:wdp / 37548 FlyBaseID:FBgn0034718 Length:677 Species:Drosophila melanogaster
Sequence 2:NP_001171678.1 Gene:SLITRK4 / 139065 HGNCID:23502 Length:837 Species:Homo sapiens


Alignment Length:557 Identity:119/557 - (21%)
Similarity:200/557 - (35%) Gaps:187/557 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 VVANATPTPARTPTGCPADCTC-------------------SLSQHTHKPL----YHLKCNSTRG 57
            :|:..|..|..||  |||.|.|                   |:|:...|||    .|:..||.:.
Human   329 IVSYQTRVPPLTP--CPAPCFCKTHPSDLGLSVNCQEKNIQSMSELIPKPLNAKKLHVNGNSIKD 391

  Fly    58 LRLTEKTFQSTVPVHSIDLSHL--------------NLTRLSHL------LDKL-PELTSA---- 97
            :.:::.|     ....:||.||              |||.|..|      :::| ||:.|.    
Human   392 VDVSDFT-----DFEGLDLLHLGSNQITVIKGDVFHNLTNLRRLYLNGNQIERLYPEIFSGLHNL 451

  Fly    98 ---DLSHNQLKDLGHLGKGLKRLNLKHNQLTSDKLRKLPQH------LQVLNLQHNNITHLPLE- 152
               .|.:|.:|::. .|......||:...|.::.|:.||.:      |..|||::|...:||:. 
Human   452 QYLYLEYNLIKEIS-AGTFDSMPNLQLLYLNNNLLKSLPVYIFSGAPLARLNLRNNKFMYLPVSG 515

  Fly   153 -LTHMHQLHQLELSHNAINCSCQTLEVRNW---LVERIVYMEHPVVCSYPLEFRGRSWLQLKQDE 213
             |..:..|.|::|..|..:|:|..:.::.|   |.:.||..|  :.|..|::|.......||.:.
Human   516 VLDQLQSLTQIDLEGNPWDCTCDLVALKLWVEKLSDGIVVKE--LKCETPVQFANIELKSLKNEI 578

  Fly   214 ICKKEKYQWFDTEENELMMGDQPAAVSAEREDEEELGKDFLPIVG-NPAAT----AKKVRSP--- 270
            :|.|              :.::|:|                |... .||.|    ...:|||   
Human   579 LCPK--------------LLNKPSA----------------PFTSPAPAITFTTPLGPIRSPPGG 613

  Fly   271 QIPL-------------------------------PSDQVEGSG--DLSETNMELKLPEETVAEP 302
            .:||                               |:.:.||.|  |.....::|:..:....:.
Human   614 PVPLSILILSILVVLILTVFVAFCLLVFVLRRNKKPTVKHEGLGNPDCGSMQLQLRKHDHKTNKK 678

  Fly   303 EAAESQLVDAAASPSVLEEHIVKDEDEDDEGSGSGGGLLIIPDPSKVKIT-------SEDDIDSD 360
            :...::    |..|..:|: :.|......:.|.:|   .:..||...|:.       .:|.:..|
Human   679 DGLSTE----AFIPQTIEQ-MSKSHTCGLKESETG---FMFSDPPGQKVVMRNVADKEKDLLHVD 735

  Fly   361 GKPEESDVRPLEN--PENSENPDTVF----------SNKIGI--YEGDQEEKKPVEEDNIVPVVM 411
            .:...|.:..|:.  |....|   ||          .|.||:  :|....||:|.::..      
Human   736 TRKRLSTIDELDELFPSRDSN---VFIQNFLESKKEYNSIGVSGFEIRYPEKQPDKKSK------ 791

  Fly   412 TNLDTGLESDVVTDGPLDSSKESEDI-LTAKIGKPKD 447
            .:|..|..|.:|.:     .::||.. |.||:....|
Human   792 KSLIGGNHSKIVVE-----QRKSEYFELKAKLQSSPD 823

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
wdpNP_001286712.1 LRR_RI <31..176 CDD:238064 51/203 (25%)
leucine-rich repeat 47..70 CDD:275378 5/26 (19%)
LRR_8 71..124 CDD:290566 19/80 (24%)
leucine-rich repeat 73..93 CDD:275378 10/40 (25%)
leucine-rich repeat 94..112 CDD:275378 4/24 (17%)
LRR_8 112..169 CDD:290566 18/64 (28%)
leucine-rich repeat 114..134 CDD:275378 5/19 (26%)
leucine-rich repeat 136..158 CDD:275378 8/23 (35%)
leucine-rich repeat 159..171 CDD:275378 4/11 (36%)
SLITRK4NP_001171678.1 LRR 1 60..81
leucine-rich repeat 63..84 CDD:275380
LRR_8 83..143 CDD:316378
LRR 2 84..105
leucine-rich repeat 85..108 CDD:275380
LRR 3 108..129
leucine-rich repeat 109..132 CDD:275380
LRR_8 132..190 CDD:316378
LRR 4 132..153
leucine-rich repeat 133..156 CDD:275380
LRR 5 156..177
leucine-rich repeat 157..179 CDD:275380
LRR 6 179..200
leucine-rich repeat 180..204 CDD:275380
leucine-rich repeat 205..295 CDD:275380
LRRCT 213..>253 CDD:214507
leucine-rich repeat 296..371 CDD:275380 11/43 (26%)
leucine-rich repeat 372..402 CDD:275380 7/34 (21%)
LRR 7 378..399 4/25 (16%)
LRR_8 402..461 CDD:316378 15/58 (26%)
LRR 8 402..423 4/20 (20%)
leucine-rich repeat 403..426 CDD:275380 6/22 (27%)
LRR 9 426..447 5/20 (25%)
leucine-rich repeat 427..450 CDD:275380 6/22 (27%)
LRR 10 450..471 4/21 (19%)
leucine-rich repeat 451..472 CDD:275380 4/21 (19%)
LRR 11 474..495 6/20 (30%)
leucine-rich repeat 475..496 CDD:275380 5/20 (25%)
LRR 12 497..518 7/20 (35%)
leucine-rich repeat 498..522 CDD:275380 8/23 (35%)
PCC 502..>563 CDD:188093 18/62 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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