Protein Alignment wdp and lrrc4

DIOPT Version :10

• Sequence 1: NP_611661.1
• Gene: wdp / 37548
• FlyBaseID: FBgn0034718
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_002939414.1
• Gene: lrrc4 / 100493671
• XenbaseID: XB-GENE-968937
• Length: 641
• Species: Xenopus tropicalis
• Alignment Length: 334
• Identity: 67/334 - (20%)
• Similarity: 106/334 - (31%)
• Gaps: 143/334 - (42%)

  Fly     4 VHLTAW-----LALFLIVVANATPTPARTPTGCPADCTCS------------------------- 38
            ||.| |     .|::|:|....:......|..||:.|:||
 Frog     9 VHHT-WKAVLFSAIYLMVHMWISCAAYSGPQSCPSVCSCSNQFSKVVCTRRGLSEVPQGIPSNTR 72

  Fly    39 -----------LSQHTHKPLYHLKC-----NSTRGLRLTEKTFQSTVPVHSIDLSHLNLTRL--- 84
                       :...|.:.|:||:.     ||.|.:.:  ..|.....:::::|....||.:
 Frog    73 SLNLMENNIQMIQADTFRHLHHLEVLQLGRNSIRQIEV--GAFNGLASLNTLELFDNWLTVIPSG 135

  Fly    85 ----------------------SHLLDKLPELTSADLSHNQLKDLGHLGKGLKR--LNLKHNQLT 125
                                  |:..:::|.|...||  .:||.|.::.:|...  .|||:..|.
 Frog   136 AFEYLSKLRELWLRNNPIESIPSYAFNRVPSLMRLDL--GELKKLEYISEGAFEGLYNLKYLNLG 198

  Fly   126 SDKLRKLP--------QHLQV-------------------------------------------- 138
            ...:|.:|        :.|::
 Frog   199 MCNIRDMPNLTPLVGLEELEISGNNFPEIKPGSFHGLRSLKKLWIMNSQINTIERNAFDDLTSLV 263

  Fly   139 -LNLQHNNITHLPLEL-THMHQLHQLELSHNAINCSCQTLEVRNWLVERIVYMEHPV------VC 195
             |||.|||:|.||.:| ..:..|.:|.|.||..:|.|..|.:..||.|.|     |.      .|
 Frog   264 ELNLAHNNVTSLPHDLFAPLKYLVELHLHHNPWDCDCDVLWLSWWLREYI-----PTNSTCCGRC 323

  Fly   196 SYPLEFRGR 204
            ..|...||:
 Frog   324 HSPPHMRGK 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
wdp	NP_611661.1	leucine-rich repeat	47..70	CDD:275378	7/27 (26%)
		LRR	<72..>169	CDD:443914	34/177 (19%)
		leucine-rich repeat	73..93	CDD:275378	4/44 (9%)
		leucine-rich repeat	94..112	CDD:275378	6/17 (35%)
		leucine-rich repeat	114..134	CDD:275378	6/29 (21%)
		leucine-rich repeat	136..158	CDD:275378	11/67 (16%)
		leucine-rich repeat	159..171	CDD:275378	5/11 (45%)
lrrc4	XP_002939414.1	LRRNT	40..71	CDD:214470	5/30 (17%)
		LRR	<69..>295	CDD:443914	41/229 (18%)
		leucine-rich repeat	71..94	CDD:275380	2/22 (9%)
		leucine-rich repeat	95..118	CDD:275380	5/24 (21%)
		leucine-rich repeat	119..142	CDD:275380	3/22 (14%)
		leucine-rich repeat	143..166	CDD:275380	1/22 (5%)
		leucine-rich repeat	167..191	CDD:275380	7/25 (28%)
		leucine-rich repeat	192..213	CDD:275380	5/20 (25%)
		leucine-rich repeat	214..237	CDD:275380	1/22 (5%)
		leucine-rich repeat	238..261	CDD:275380	0/22 (0%)
		leucine-rich repeat	262..283	CDD:275380	10/20 (50%)
		LRRCT	294..345	CDD:214507	13/44 (30%)
		IG_like	353..435	CDD:214653
		Ig strand B	364..368	CDD:409353
		Ig strand C	376..379	CDD:409353
		Ig strand E	402..405	CDD:409353
		Ig strand F	415..420	CDD:409353
		Ig strand G	428..431	CDD:409353