DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5819 and RLP15

DIOPT Version :9

Sequence 1:	NP_001246458.1	Gene:	CG5819 / 37547	FlyBaseID:	FBgn0034717	Length:	915	Species:	Drosophila melanogaster
Sequence 2:	NP_177559.1	Gene:	RLP15 / 843759	AraportID:	AT1G74190	Length:	965	Species:	Arabidopsis thaliana

Alignment Length:	894	Identity:	194/894 - (21%)
Similarity:	309/894 - (34%)	Gaps:	291/894 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LALLVLGVISSCRAVNCPWPCRCTWVVDSLYADCSRRSLQTYPNFDGIPVEHLDLSGNKFLE--F 69
            |.|.:|......|::|.. ..||:.:.|.:....|.|.|:        .:|.|||:.|||..  |
plant    94 LNLSLLHPFEDVRSLNLS-SSRCSGLFDDVEGYKSLRKLR--------KLEILDLASNKFNNSIF 149

  Fly    70 PTLYADIDSLIYLDLSSNYI-SSIGAKTLIGFTSLRTLLLANNSIDSWESLSPNEAFKYAPSLKR 133
            ..|.| ..||..|.|.||.: .|..||.|...|:|..|.|:.|..:.  |: |.:.......||.
plant   150 HFLSA-ATSLTTLFLRSNNMDGSFPAKELRDLTNLELLDLSRNRFNG--SI-PIQELSSLRKLKA 210

  Fly   134 LGLDGNRLGSFGNGESFELLTSSSLTDLGLS-SCGISSIGGDQMVNQLPNLERLNLANNQLAQIA 197
            |.|.||....     |.| |.....|||..| ..||.         :|.|::.|:|:.|:|  :.
plant   211 LDLSGNEFSG-----SME-LQGKFCTDLLFSIQSGIC---------ELNNMQELDLSQNKL--VG 258

  Fly   198 ALPS-----RTLRVLDLSNCSIKNLSGFFLDAMQNLEALNL------------------------ 233
            .|||     ..|||||||:..:.......|.::|:||.|:|
plant   259 HLPSCLTSLTGLRVLDLSSNKLTGTVPSSLGSLQSLEYLSLFDNDFEGSFSFGSLANLSNLMVLK 323

  Fly   234 --SRNTELQFDSLSE-------------------DPILTYMLRKLDVSYCNLDSIELSG-LP--- 273
              |:::.||.  |||                   :.:..::|.:.|:.:.:|....:|| ||
plant   324 LCSKSSSLQV--LSESSWKPKFQLSVIALRSCNMEKVPHFLLHQKDLRHVDLSDNNISGKLPSWL 386

  Fly   274 -----QLTEVRLQGNLLRVVDVNTFANNSMLEVVDLSQNVLRHIGQDAFAKL-KRLKELNLAFN- 331
                 :|..:.||.||.....:...|:|  |..:|:|.|...|:..:....: ..|:.||.:.|
plant   387 LANNTKLKVLLLQNNLFTSFQIPKSAHN--LLFLDVSANDFNHLFPENIGWIFPHLRYLNTSKNN 449

  Fly   332 ------------------EIAR------LDRNFIRNNDVLVELNLSRNVLQ-------------- 358
                              :::|      |.|:|:.....:..|.||.|.|.
plant   450 FQENLPSSLGNMNGIQYMDLSRNSFHGNLPRSFVNGCYSMAILKLSHNKLSGEIFPESTNFTNIL 514

  Fly   359 -----------------------KLTKIVSNSVRTINMSWC-EITSIESTALS------------ 387
                                   :|..:.:|::..:..||. |:.|:.:..:|
plant   515 GLFMDNNLFTGKIGQGLRSLINLELLDMSNNNLTGVIPSWIGELPSLTALLISDNFLKGDIPMSL 579

  Fly   388 -SLSVIQKLDLS---------------NNLITDMPTFMRSETLQQLNLANCRLTTVRNNTFR-EF 435
             :.|.:|.||||               |.::..:.....|.|:....|||..:..:|||.|. :.
plant   580 FNKSSLQLLDLSANSLSGVIPPQHDSRNGVVLLLQDNKLSGTIPDTLLANVEILDLRNNRFSGKI 644

  Fly   436 PELADLH------LNGNRLTSPIPPNYFDGNKFLDQLWLGD---NPWICDCHSPLFVDF------ 485
            ||..::.      |.||..|..| |:...|...:..|.|.:   |..|..|.|.....|
plant   645 PEFINIQNISILLLRGNNFTGQI-PHQLCGLSNIQLLDLSNNRLNGTIPSCLSNTSFGFGKECTS 708

  Fly   486 --YDYLTAKPAKIKDRNHLRCAAPAVFYGKLWEFACADVWILNARTSSTGEKAWSIIMLTLLGLG 548
              ||:..:.|:.             ||.|            .:.....:..|...|...:||.|.
plant   709 YDYDFGISFPSD-------------VFNG------------FSLHQDFSSNKNGGIYFKSLLTLD 748

  Fly   549 ALVLGYACLQKYLRKRKVRQSDRE----YEENDDELRRIRDLNERILREE-----------ATPS 598
            .|.:.|    |...:.|:..:.:.    |...:.:|....||:|..|..|           ...:
plant   749 PLSMDY----KAATQTKIEFATKHRYDAYMGGNLKLLFGMDLSENELSGEIPVEFGGLLELRALN 809

  Fly   599 LQHTQEISLLPSYEDAL---------------RMPKLVRPVKSMM-------DLSG--------- 632
            |.|.....::|....::               |:|..:..:.|:.       :|||
plant   810 LSHNNLSGVIPKSISSMEKMESFDLSFNRLQGRIPSQLTELTSLSVFKVSHNNLSGVIPQGRQFN 874

  Fly   633 ---PERARNSRKLRRSQTHAD-GDGSQSEAEDGLQLDSRQRFRSVEMLS 677
               .|....:|.|....|:.. .:.|..||::|::.|.    ..::|:|
plant   875 TFDAESYFGNRLLCGQPTNRSCNNNSYEEADNGVEADE----SIIDMVS 919

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5819	NP_001246458.1	leucine-rich repeat	56..78	CDD:275380	10/23 (43%)
		LRR_RI	<58..236	CDD:238064	64/212 (30%)
		LRR_8	78..141	CDD:290566	23/63 (37%)
		leucine-rich repeat	79..102	CDD:275380	9/23 (39%)
		leucine-rich repeat	103..130	CDD:275380	6/26 (23%)
		leucine-rich repeat	131..155	CDD:275380	9/23 (39%)
		LRR_8	156..214	CDD:290566	22/63 (35%)
		leucine-rich repeat	158..182	CDD:275380	7/24 (29%)
		LRR_8	202..285	CDD:290566	30/136 (22%)
		leucine-rich repeat	204..227	CDD:275380	8/22 (36%)
		leucine-rich repeat	254..274	CDD:275380	7/28 (25%)
		LRR_8	273..333	CDD:290566	17/87 (20%)
		leucine-rich repeat	275..298	CDD:275380	7/22 (32%)
		LRR_RI	277..>471	CDD:238064	58/295 (20%)
		leucine-rich repeat	299..322	CDD:275380	5/23 (22%)
		LRR_8	321..402	CDD:290566	27/171 (16%)
		leucine-rich repeat	323..346	CDD:275380	8/47 (17%)
		leucine-rich repeat	347..391	CDD:275380	12/94 (13%)
		leucine-rich repeat	392..413	CDD:275380	7/35 (20%)
		LRR_8	393..448	CDD:290566	20/76 (26%)
		leucine-rich repeat	414..437	CDD:275380	7/23 (30%)
		LRRCT	471..517	CDD:214507	11/53 (21%)
RLP15	NP_177559.1	LRRNT_2	28..72	CDD:369783
		PLN00113	<105..>287	CDD:215061	66/211 (31%)
		leucine-rich repeat	106..133	CDD:275380	8/35 (23%)
		leucine-rich repeat	134..157	CDD:275380	10/23 (43%)
		leucine-rich repeat	158..182	CDD:275380	9/23 (39%)
		leucine-rich repeat	183..207	CDD:275380	6/26 (23%)
		leucine-rich repeat	208..245	CDD:275380	16/51 (31%)
		leucine-rich repeat	246..269	CDD:275380	7/24 (29%)
		PLN00113	249..>892	CDD:215061	131/678 (19%)
		leucine-rich repeat	270..293	CDD:275380	8/22 (36%)
		leucine-rich repeat	294..318	CDD:275380	4/23 (17%)
		leucine-rich repeat	319..357	CDD:275380	6/39 (15%)
		leucine-rich repeat	368..392	CDD:275380	5/23 (22%)
		leucine-rich repeat	440..463	CDD:275380	4/22 (18%)
		leucine-rich repeat	465..488	CDD:275380	4/22 (18%)
		leucine-rich repeat	489..512	CDD:275380	5/22 (23%)
		leucine-rich repeat	513..536	CDD:275380	0/22 (0%)
		leucine-rich repeat	537..560	CDD:275380	5/22 (23%)
		leucine-rich repeat	561..584	CDD:275380	1/22 (5%)
		leucine-rich repeat	585..607	CDD:275380	5/21 (24%)
		leucine-rich repeat	608..629	CDD:275380	3/20 (15%)
		leucine-rich repeat	630..652	CDD:275380	6/21 (29%)
		leucine-rich repeat	653..676	CDD:275380	7/23 (30%)
		leucine-rich repeat	677..697	CDD:275380	5/19 (26%)
		leucine-rich repeat	744..804	CDD:275380	14/63 (22%)
		leucine-rich repeat	749..780	CDD:275380	5/34 (15%)
		leucine-rich repeat	805..828	CDD:275380	3/22 (14%)
		leucine-rich repeat	829..850	CDD:275380	2/20 (10%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000