Protein Alignment CG5819 and igfals

DIOPT Version :10

• Sequence 1: NP_611660.1
• Gene: CG5819 / 37547
• FlyBaseID: FBgn0034717
• Length: 915
• Species: Drosophila melanogaster
• Sequence 2: XP_003198203.1
• Gene: igfals / 570758
• ZFINID: ZDB-GENE-061009-25
• Length: 614
• Species: Danio rerio
• Alignment Length: 580
• Identity: 148/580 - (25%)
• Similarity: 238/580 - (41%)
• Gaps: 128/580 - (22%)

  Fly    26 PCR--CTWVVD----SLYADCSRRSLQTYPNFDGIPVEHLDLSGNKF-------------LEFPT 71
            ||.  ||.:.|    .|...||.|:....|:...:....|.|.||.|             |||..
Zfish    48 PCAKGCTCLQDDYSLELNVYCSTRNFTQVPSDIPLSTRSLWLDGNLFSNLPAGAFEKLTNLEFLN 112

  Fly    72 L------------YADIDSLIYLDLSSNYISSIGAKTLIGFTSLRTLLLANNS---ID------- 114
            |            :..::||.:|.|..|.:.|:......|.::|.||.|.||.   ||
Zfish   113 LQSSLLVSLDAHAFRGLNSLAHLHLERNNLRSLSGLVFQGTSNLATLSLNNNQMFRIDDRLFAGM 177

  Fly   115 --------SWESLS--PNEAFKYAPSLKRLGLDGNRLGSFGNGESFELLTSSSLTDLGLSSCGIS 169
                    .|..||  |...|:....|:.|.|.|||| ::...:.|:.|  :.|.:|.|:...:.
Zfish   178 SHMWLLNLGWNLLSVLPETGFQDLHGLRELILAGNRL-AYLQPQLFQGL--NELKELDLTGNYLK 239

  Fly   170 SIGGDQMVNQLPNLERLNLANNQLAQIAA---LPSRTLRVLDLSNCSIKNLSGFFLDAMQNLEAL 231
            .|..:..: :||.|::|.|..||:..:|.   :..::||.||||...:..|.......:|:|..|
Zfish   240 VIKANVFL-KLPKLQKLYLGQNQIVTVAPRAFVGMKSLRWLDLSRNRLTVLHDETFIGLQSLHVL 303

  Fly   232 NLSRNT----------ELQFDSLSEDPILTYMLRKLDVSYCNLDSIELSGLPQLTEVRLQGNLLR 286
            .||.|:          :||:  |.|..:....:|.|.|..       ..||..|..:.|:.|.|:
Zfish   304 RLSNNSINSLRPGTFRDLQY--LEELCLYHNQIRALGVRV-------FEGLGHLEVLNLENNRLQ 359

  Fly   287 VVDVNTFANNSMLEVVDLSQNVLRHIGQDAFAKLKRLKELNL-----------AFNEIARLDRNF 340
            ...:.||...:.|.|:.|:.:....:....|..|.:|..::|           :|:.:..|.|.|
Zfish   360 EARMGTFMGLNHLAVMKLTGSCFHSLPDQVFKGLSKLHSIHLDRSCLTKVSSQSFSGLTGLRRLF 424

  Fly   341 IRNNDVLVELNLSRNVLQKLTKIVSNSVRTINMSWCEITSIESTALSSLSVIQKLDLSNNLITDM 405
            :::|::.:....|...||:|        :.:::.:.::|:|.|.....|..:..|.||.||:.::
Zfish   425 LQHNNISLVERQSFVELQRL--------QQLDLRFNKLTTITSNTFYGLKNLDYLLLSGNLLHNL 481

  Fly   406 P--TFMRSETLQQLNLANCRLTTVRNNTFREFPELADLHLNGNRLTS---PIPPNYFDGNKFLDQ 465
            |  ..:..:.|..|:|:..:|..:.|.|....|.|..|:|..|.|.:   .||.:       |||
Zfish   482 PAEALLPLQHLSWLDLSGNKLELILNATIYMLPRLRYLNLKDNILVNLPVSIPES-------LDQ 539

  Fly   466 LWLGDNPWICDCHSPLFVDFYDYLTAKP-----------------AKIKDRNHLRCAAPA 508
            |||..|.|.|||.:.   .|.|::..||                 ..|...|::.||:|:
Zfish   540 LWLSGNNWKCDCSAK---PFRDFILQKPQVVPLQVEMLGEGEEPHTLITVYNNVTCASPS 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5819	NP_611660.1	RNA1	<56..193	CDD:444072	48/181 (27%)
		leucine-rich repeat	56..78	CDD:275380	9/46 (20%)
		leucine-rich repeat	79..102	CDD:275380	6/22 (27%)
		leucine-rich repeat	103..130	CDD:275380	13/46 (28%)
		leucine-rich repeat	131..155	CDD:275380	9/23 (39%)
		LRR	134..>466	CDD:443914	90/360 (25%)
		leucine-rich repeat	158..182	CDD:275380	5/23 (22%)
		leucine-rich repeat	204..227	CDD:275380	7/22 (32%)
		leucine-rich repeat	254..274	CDD:275380	5/19 (26%)
		leucine-rich repeat	275..298	CDD:275380	6/22 (27%)
		leucine-rich repeat	299..322	CDD:275380	5/22 (23%)
		leucine-rich repeat	323..346	CDD:275380	7/33 (21%)
		leucine-rich repeat	347..391	CDD:275380	8/43 (19%)
		leucine-rich repeat	392..413	CDD:275380	6/22 (27%)
		leucine-rich repeat	414..437	CDD:275380	6/22 (27%)
		LRRCT	471..517	CDD:214507	14/55 (25%)
igfals	XP_003198203.1	LRRNT	48..81	CDD:396168	10/32 (31%)
		leucine-rich repeat	65..83	CDD:275380	4/17 (24%)
		leucine-rich repeat	84..107	CDD:275380	5/22 (23%)
		LRR_8	85..142	CDD:404697	14/56 (25%)
		leucine-rich repeat	108..131	CDD:275380	4/22 (18%)
		LRR_8	131..214	CDD:404697	25/82 (30%)
		leucine-rich repeat	132..155	CDD:275380	6/22 (27%)
		leucine-rich repeat	156..203	CDD:275380	13/46 (28%)
		LRR	<196..507	CDD:443914	80/331 (24%)
		leucine-rich repeat	204..227	CDD:275380	9/25 (36%)
		leucine-rich repeat	228..251	CDD:275380	5/23 (22%)
		leucine-rich repeat	252..275	CDD:275380	6/22 (27%)
		leucine-rich repeat	276..299	CDD:275380	7/22 (32%)
		leucine-rich repeat	300..323	CDD:275380	6/22 (27%)
		leucine-rich repeat	324..347	CDD:275380	7/29 (24%)
		leucine-rich repeat	348..369	CDD:275380	6/20 (30%)
		leucine-rich repeat	396..419	CDD:275380	3/22 (14%)
		leucine-rich repeat	420..443	CDD:275380	6/22 (27%)
		leucine-rich repeat	444..467	CDD:275380	5/30 (17%)
		leucine-rich repeat	468..486	CDD:275380	6/17 (35%)
		leucine-rich repeat	492..515	CDD:275380	6/22 (27%)
		leucine-rich repeat	516..540	CDD:275380	9/30 (30%)