DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5819 and Lingo4

DIOPT Version :9

Sequence 1:NP_001246458.1 Gene:CG5819 / 37547 FlyBaseID:FBgn0034717 Length:915 Species:Drosophila melanogaster
Sequence 2:NP_001102659.1 Gene:Lingo4 / 499668 RGDID:1562025 Length:618 Species:Rattus norvegicus


Alignment Length:528 Identity:139/528 - (26%)
Similarity:198/528 - (37%) Gaps:157/528 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 VLELALLVLGVISSCRAVNCPWPCRCTWVVDSLYADCSRRSLQTYPNFDGIPV--EHLDLSGNKF 66
            :|.|.||..|.|||     ||..|.||....::.  |:.|.|.|.|.  |:|:  |.||||||:.
  Rat    42 LLFLLLLPGGSISS-----CPTLCDCTSQTRAVL--CAHRRLDTVPG--GLPLDTEVLDLSGNRL 97

  Fly    67 LEFPT-LYADIDSLIYLDLSSNYISSIGAKTLIGFTSLRTLLLANNSIDSWESLSPNEAFKYAPS 130
            ..... :.:.:..|..||||.|.:|                           :|.|. ||....|
  Rat    98 WGLQRGMLSRLGQLQELDLSYNQLS---------------------------TLEPG-AFHGLQS 134

  Fly   131 LKRLGLDGNRLGSFGNGESFELLTSSSLTDLGLSSCGISSIGGDQMVNQLPNLERLNLANNQLAQ 195
            |..|.|.||||...|.| .|..|::.:|.||.|:...:..   |....:|.:|::|.:.:|.|..
  Rat   135 LLTLRLQGNRLRIVGPG-IFSGLSALTLLDLRLNQIVLFL---DGAFGELGSLQQLEVGDNHLVF 195

  Fly   196 IAALPSRTLRVLDLSNCSIKNLSGFFLDAMQNLEALNLSRNTELQFDSLSEDPILTYMLRKLDVS 260
            :|                    .|.| ..:..|..:.|.|                         
  Rat   196 VA--------------------PGAF-SGLAKLSTITLER------------------------- 214

  Fly   261 YCNLDSI---ELSGLPQLTEVRLQGNLLRVVDVNTFANNSMLEVVDLSQNVLRHIGQDAFAKLKR 322
             |||.::   .|:.||.|..:||:                .|::..|....||.:||        
  Rat   215 -CNLSTVPGLALAQLPALVALRLR----------------ELDIERLPSGALRGLGQ-------- 254

  Fly   323 LKELNL-AFNEIARLDRNFIRNNDVLVELNLSRNVLQKLTKIVSNSVRTINMSWCEITSIESTAL 386
            ||||.: .:..:..||..      .||.||||                ::.::.|.::|:...||
  Rat   255 LKELEIHHWPSLEALDPG------SLVGLNLS----------------SLAITHCNLSSVPFQAL 297

  Fly   387 SSLSVIQKLDLSNNLITDMPTFMRSE--TLQQLNLANCRLTTVRNNTFREFPELADLHLNGNRLT 449
            ..||.:|.||||.|.|:.:|....|.  .||:|.|:...||::..:.|........|.:..|.|.
  Rat   298 HHLSFLQVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQ 362

  Fly   450 SPIPPNYFDGNKFLDQLWLGDNPWICDCHSPLFVDF---YDYLTAKPAKIKDRNHLRCAAPAVFY 511
            : :....|.....|..|.|..||..|||.....:..   .|:.|:.||         ||.|....
  Rat   363 T-LEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLRLRRRLDFGTSPPA---------CAGPQHVQ 417

  Fly   512 GK-LWEFA 518
            || |.||:
  Rat   418 GKNLREFS 425

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5819NP_001246458.1 leucine-rich repeat 56..78 CDD:275380 7/24 (29%)
LRR_RI <58..236 CDD:238064 44/178 (25%)
LRR_8 78..141 CDD:290566 17/62 (27%)
leucine-rich repeat 79..102 CDD:275380 7/22 (32%)
leucine-rich repeat 103..130 CDD:275380 4/26 (15%)
leucine-rich repeat 131..155 CDD:275380 11/23 (48%)
LRR_8 156..214 CDD:290566 11/57 (19%)
leucine-rich repeat 158..182 CDD:275380 6/23 (26%)
LRR_8 202..285 CDD:290566 14/85 (16%)
leucine-rich repeat 204..227 CDD:275380 2/22 (9%)
leucine-rich repeat 254..274 CDD:275380 5/22 (23%)
LRR_8 273..333 CDD:290566 14/60 (23%)
leucine-rich repeat 275..298 CDD:275380 3/22 (14%)
LRR_RI 277..>471 CDD:238064 49/196 (25%)
leucine-rich repeat 299..322 CDD:275380 6/22 (27%)
LRR_8 321..402 CDD:290566 24/81 (30%)
leucine-rich repeat 323..346 CDD:275380 6/23 (26%)
leucine-rich repeat 347..391 CDD:275380 11/43 (26%)
leucine-rich repeat 392..413 CDD:275380 9/22 (41%)
LRR_8 393..448 CDD:290566 18/56 (32%)
leucine-rich repeat 414..437 CDD:275380 7/22 (32%)
LRRCT 471..517 CDD:214507 15/49 (31%)
Lingo4NP_001102659.1 leucine-rich repeat 87..110 CDD:275380 7/22 (32%)
LRR_8 88..145 CDD:290566 24/84 (29%)
LRR_4 88..126 CDD:289563 15/64 (23%)
LRR_RI 110..345 CDD:238064 87/359 (24%)
leucine-rich repeat 111..134 CDD:275380 11/50 (22%)
LRR_8 134..193 CDD:290566 21/62 (34%)
leucine-rich repeat 135..158 CDD:275380 11/23 (48%)
leucine-rich repeat 159..182 CDD:275380 6/25 (24%)
LRR_8 182..237 CDD:290566 18/101 (18%)
leucine-rich repeat 183..206 CDD:275380 7/43 (16%)
leucine-rich repeat 207..230 CDD:275380 8/48 (17%)
leucine-rich repeat 231..254 CDD:275380 7/38 (18%)
leucine-rich repeat 255..302 CDD:275380 17/68 (25%)
LRR_8 278..334 CDD:290566 22/71 (31%)
leucine-rich repeat 303..326 CDD:275380 9/22 (41%)
LRR_8 326..385 CDD:290566 15/59 (25%)
leucine-rich repeat 327..348 CDD:275380 7/20 (35%)
leucine-rich repeat 351..374 CDD:275380 4/23 (17%)
IG_like 445..526 CDD:214653
Ig 456..526 CDD:299845
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166348967
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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