Protein Alignment CG5819 and Lingo4

DIOPT Version :10

• Sequence 1: NP_611660.1
• Gene: CG5819 / 37547
• FlyBaseID: FBgn0034717
• Length: 915
• Species: Drosophila melanogaster
• Sequence 2: NP_001102659.1
• Gene: Lingo4 / 499668
• RGDID: 1562025
• Length: 618
• Species: Rattus norvegicus
• Alignment Length: 528
• Identity: 139/528 - (26%)
• Similarity: 198/528 - (37%)
• Gaps: 157/528 - (29%)

  Fly     4 VLELALLVLGVISSCRAVNCPWPCRCTWVVDSLYADCSRRSLQTYPNFDGIPV--EHLDLSGNKF 66
            :|.|.||..|.|||     ||..|.||....::.  |:.|.|.|.|.  |:|:  |.||||||:.
  Rat    42 LLFLLLLPGGSISS-----CPTLCDCTSQTRAVL--CAHRRLDTVPG--GLPLDTEVLDLSGNRL 97

  Fly    67 LEFPT-LYADIDSLIYLDLSSNYISSIGAKTLIGFTSLRTLLLANNSIDSWESLSPNEAFKYAPS 130
            ..... :.:.:..|..||||.|.:|                           :|.|. ||....|
  Rat    98 WGLQRGMLSRLGQLQELDLSYNQLS---------------------------TLEPG-AFHGLQS 134

  Fly   131 LKRLGLDGNRLGSFGNGESFELLTSSSLTDLGLSSCGISSIGGDQMVNQLPNLERLNLANNQLAQ 195
            |..|.|.||||...|.| .|..|::.:|.||.|:...:..   |....:|.:|::|.:.:|.|..
  Rat   135 LLTLRLQGNRLRIVGPG-IFSGLSALTLLDLRLNQIVLFL---DGAFGELGSLQQLEVGDNHLVF 195

  Fly   196 IAALPSRTLRVLDLSNCSIKNLSGFFLDAMQNLEALNLSRNTELQFDSLSEDPILTYMLRKLDVS 260
            :|                    .|.| ..:..|..:.|.|
  Rat   196 VA--------------------PGAF-SGLAKLSTITLER------------------------- 214

  Fly   261 YCNLDSI---ELSGLPQLTEVRLQGNLLRVVDVNTFANNSMLEVVDLSQNVLRHIGQDAFAKLKR 322
             |||.::   .|:.||.|..:||:                .|::..|....||.:||
  Rat   215 -CNLSTVPGLALAQLPALVALRLR----------------ELDIERLPSGALRGLGQ-------- 254

  Fly   323 LKELNL-AFNEIARLDRNFIRNNDVLVELNLSRNVLQKLTKIVSNSVRTINMSWCEITSIESTAL 386
            ||||.: .:..:..||..      .||.||||                ::.::.|.::|:...||
  Rat   255 LKELEIHHWPSLEALDPG------SLVGLNLS----------------SLAITHCNLSSVPFQAL 297

  Fly   387 SSLSVIQKLDLSNNLITDMPTFMRSE--TLQQLNLANCRLTTVRNNTFREFPELADLHLNGNRLT 449
            ..||.:|.||||.|.|:.:|....|.  .||:|.|:...||::..:.|........|.:..|.|.
  Rat   298 HHLSFLQVLDLSQNPISAIPARRLSPLVRLQELRLSGACLTSIAAHAFHGLTAFHLLDVADNALQ 362

  Fly   450 SPIPPNYFDGNKFLDQLWLGDNPWICDCHSPLFVDF---YDYLTAKPAKIKDRNHLRCAAPAVFY 511
            : :....|.....|..|.|..||..|||.....:..   .|:.|:.||         ||.|....
  Rat   363 T-LEETAFPSPDKLVTLRLSGNPLTCDCRLLWLLRLRRRLDFGTSPPA---------CAGPQHVQ 417

  Fly   512 GK-LWEFA 518
            || |.||:
  Rat   418 GKNLREFS 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5819	NP_611660.1	RNA1	<56..193	CDD:444072	39/139 (28%)
		leucine-rich repeat	56..78	CDD:275380	7/24 (29%)
		leucine-rich repeat	79..102	CDD:275380	7/22 (32%)
		leucine-rich repeat	103..130	CDD:275380	4/26 (15%)
		leucine-rich repeat	131..155	CDD:275380	11/23 (48%)
		LRR	134..>466	CDD:443914	80/337 (24%)
		leucine-rich repeat	158..182	CDD:275380	6/23 (26%)
		leucine-rich repeat	204..227	CDD:275380	2/22 (9%)
		leucine-rich repeat	254..274	CDD:275380	5/22 (23%)
		leucine-rich repeat	275..298	CDD:275380	3/22 (14%)
		leucine-rich repeat	299..322	CDD:275380	6/22 (27%)
		leucine-rich repeat	323..346	CDD:275380	6/23 (26%)
		leucine-rich repeat	347..391	CDD:275380	11/43 (26%)
		leucine-rich repeat	392..413	CDD:275380	9/22 (41%)
		leucine-rich repeat	414..437	CDD:275380	7/22 (32%)
		LRRCT	471..517	CDD:214507	15/49 (31%)
Lingo4	NP_001102659.1	leucine-rich repeat	87..110	CDD:275380	7/22 (32%)
		LRR	<88..441	CDD:443914	119/473 (25%)
		leucine-rich repeat	111..134	CDD:275380	11/50 (22%)
		leucine-rich repeat	135..158	CDD:275380	11/23 (48%)
		leucine-rich repeat	159..182	CDD:275380	6/25 (24%)
		leucine-rich repeat	183..206	CDD:275380	7/43 (16%)
		leucine-rich repeat	207..230	CDD:275380	8/48 (17%)
		leucine-rich repeat	231..254	CDD:275380	7/38 (18%)
		leucine-rich repeat	255..302	CDD:275380	17/68 (25%)
		leucine-rich repeat	303..326	CDD:275380	9/22 (41%)
		leucine-rich repeat	327..348	CDD:275380	7/20 (35%)
		leucine-rich repeat	351..374	CDD:275380	4/23 (17%)
		IG_like	445..526	CDD:214653
		Ig strand B	456..460	CDD:409353
		Ig strand C	469..473	CDD:409353
		Ig strand E	492..496	CDD:409353
		Ig strand F	506..511	CDD:409353
		Ig strand G	519..522	CDD:409353