DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG5819 and conv

DIOPT Version :9

Sequence 1:NP_001246458.1 Gene:CG5819 / 37547 FlyBaseID:FBgn0034717 Length:915 Species:Drosophila melanogaster
Sequence 2:NP_001286416.1 Gene:conv / 36588 FlyBaseID:FBgn0261269 Length:1092 Species:Drosophila melanogaster


Alignment Length:710 Identity:171/710 - (24%)
Similarity:284/710 - (40%) Gaps:180/710 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 ADCSRRSLQ-----TY--------PNFDGIPVEH------LDLSGNKFLE-----FPTLYADIDS 78
            |:.||||..     ||        .|...||:::      |:.|.|...|     ||.||    .
  Fly   402 ANFSRRSFDETTFATYFQLSYNNLTNLAQIPIQNMTGLKVLNASYNSITEIPKNCFPKLY----E 462

  Fly    79 LIYLDLSSNYISSIGAKTLIGFTSLRTLLLANNSIDSWESLSPNEAFKYAPSLKRLGLDGNRLGS 143
            |..:|:|.|.||||.........|||::.|::||:...:|    ..|...|:|..:.|..|.|.|
  Fly   463 LHTIDVSHNNISSIFNGVFQTLFSLRSIDLSHNSMREIKS----STFGTLPTLLEMDLSHNELVS 523

  Fly   144 FGNGESFELLTSSSLTDLGLSSCGISSIGGDQMVNQLPNLERLNLANNQL----AQIAALPSRT- 203
            ...|...:|   :||..|.|::            |||..|.:|.::.|:|    .::..:||.| 
  Fly   524 VVRGSLAKL---TSLRQLYLNN------------NQLEKLFQLPISLNELYFSHNRLTNIPSGTW 573

  Fly   204 -----LRVLDLSNCSIKNLSGFFLDAMQNLEALNLSRNTELQFDSLSEDP----ILTYMLRKLDV 259
                 |..||||:    |..|..|:. ::...|.:.:..:||.:.:|:.|    .:...|:.|.:
  Fly   574 PVMNSLIYLDLSH----NQLGDTLNG-ESFTGLLVVQRLKLQNNGISQPPKDAVAVMSTLQYLHL 633

  Fly   260 SYCNLDSIELSG---LPQLTEVRLQGNLLRVVDVNTFANNSMLEVVDLSQNVLRHIGQDAFAKLK 321
            ...|:.::|.|.   ||.|.|:.|.||.::.:....|.....|..::||.|.::.:..|.|..|.
  Fly   634 ENNNITTLERSAFGKLPVLFELNLYGNQVKDISKRAFEGLLQLLTLNLSSNGIQTLQNDIFVGLP 698

  Fly   322 RLKELNLAFNEIARLDRNFIRNNDVLVE------LNLSRNVLQKLTK-------IVSNSVRTINM 373
            .|:.|:|:||.:.:||.   :.|.||.:      |:||.|.:..:||       .:..::|.:|:
  Fly   699 SLRNLDLSFNSLTKLDN---KTNGVLDDLLSLETLDLSHNRISFVTKKTFPSHQYIPYNLRNLNL 760

  Fly   374 SW------------------------CEITSIESTALSSLSVIQKLDLSNNLITDMPT----FMR 410
            |:                        .:|..:....:|:.:.:|.||:|.|.::::.:    |..
  Fly   761 SYNLMPILTYDITFGTKKLVRLDVSHNQINDLRRGVISNFTSLQSLDMSYNELSNLKSEEHIFDL 825

  Fly   411 SETLQQLNLANCRLTTVRNNTFREFPELADLHLNGNRLTSPIPPNYFDGNKFLDQLWLGDNPWIC 475
            .:.|..|:|::.::..:......:...|..:.|..|.| ..:|.:.....:...|:.|..||..|
  Fly   826 PQNLSWLDLSHNKIYHLPFANLVKVKSLKYVDLTNNSL-EDVPASIVGSMRNGSQVLLAGNPLHC 889

  Fly   476 DCHS-PL--FV--------DFYDYLTAKPAKIKDR-------NHLRCAA------PAVFYGKLWE 516
            .|:: ||  |:        |........||.|||:       .:|.||.      ..:.|.:|  
  Fly   890 GCNARPLKYFMLQQTIAGEDLKSIYCGTPALIKDKQLISLDDEYLHCAEDEQEMYKGIDYEQL-- 952

  Fly   517 FACADVWILNARTSSTGEKAWSIIMLTLLGLGALVLGYACLQK---YLRKRK---VRQSDREYEE 575
               .||.....:|:..|       ||||..   .|.|::.:..   |:|...   :.|||..|..
  Fly   953 ---TDVRFREVKTNKAG-------MLTLCW---YVSGFSDVSDFHVYIRSSSNDVLHQSDYAYNN 1004

  Fly   576 NDDEL--RRIRDLNERILREEATPSLQHTQEISLLPSYED----------ALRMPKLVRP 623
            ...::  ..:..|.|..||         ..||.::....|          ..::|.|.||
  Fly  1005 RTAQIPVEELSTLGEEKLR---------GAEICIVSRDSDGNTRKWFSGQCQQLPSLKRP 1055

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG5819NP_001246458.1 leucine-rich repeat 56..78 CDD:275380 8/32 (25%)
LRR_RI <58..236 CDD:238064 55/198 (28%)
LRR_8 78..141 CDD:290566 20/62 (32%)
leucine-rich repeat 79..102 CDD:275380 8/22 (36%)
leucine-rich repeat 103..130 CDD:275380 7/26 (27%)
leucine-rich repeat 131..155 CDD:275380 7/23 (30%)
LRR_8 156..214 CDD:290566 19/67 (28%)
leucine-rich repeat 158..182 CDD:275380 6/23 (26%)
LRR_8 202..285 CDD:290566 26/95 (27%)
leucine-rich repeat 204..227 CDD:275380 8/22 (36%)
leucine-rich repeat 254..274 CDD:275380 6/22 (27%)
LRR_8 273..333 CDD:290566 19/59 (32%)
leucine-rich repeat 275..298 CDD:275380 6/22 (27%)
LRR_RI 277..>471 CDD:238064 49/234 (21%)
leucine-rich repeat 299..322 CDD:275380 7/22 (32%)
LRR_8 321..402 CDD:290566 26/117 (22%)
leucine-rich repeat 323..346 CDD:275380 8/22 (36%)
leucine-rich repeat 347..391 CDD:275380 12/80 (15%)
leucine-rich repeat 392..413 CDD:275380 6/24 (25%)
LRR_8 393..448 CDD:290566 12/58 (21%)
leucine-rich repeat 414..437 CDD:275380 3/22 (14%)
LRRCT 471..517 CDD:214507 18/69 (26%)
convNP_001286416.1 leucine-rich repeat 125..148 CDD:275380
leucine-rich repeat 150..175 CDD:275380
leucine-rich repeat 176..199 CDD:275380
LRR_8 198..258 CDD:290566
leucine-rich repeat 200..223 CDD:275380
LRR_RI 201..545 CDD:238064 47/165 (28%)
leucine-rich repeat 224..271 CDD:275380
LRR_8 245..306 CDD:290566
leucine-rich repeat 272..295 CDD:275380
LRR_8 296..354 CDD:290566
leucine-rich repeat 296..319 CDD:275380
LRR_8 322..401 CDD:290566
leucine-rich repeat 322..343 CDD:275380
leucine-rich repeat 344..367 CDD:275380
leucine-rich repeat 371..390 CDD:275380
leucine-rich repeat 391..414 CDD:275380 5/11 (45%)
leucine-rich repeat 416..438 CDD:275380 5/21 (24%)
LRR_8 437..495 CDD:290566 20/61 (33%)
leucine-rich repeat 439..462 CDD:275380 8/26 (31%)
leucine-rich repeat 463..486 CDD:275380 8/22 (36%)
LRR_RI 486..738 CDD:238064 77/278 (28%)
LRR_8 486..545 CDD:290566 21/77 (27%)
leucine-rich repeat 487..510 CDD:275380 7/26 (27%)
leucine-rich repeat 511..534 CDD:275380 7/25 (28%)
leucine-rich repeat 535..554 CDD:275380 8/30 (27%)
LRR_8 554..614 CDD:290566 16/64 (25%)
leucine-rich repeat 555..578 CDD:275380 5/22 (23%)
leucine-rich repeat 579..603 CDD:275380 9/28 (32%)
leucine-rich repeat 604..627 CDD:275380 4/22 (18%)
LRR_8 626..710 CDD:290566 25/83 (30%)
leucine-rich repeat 628..649 CDD:275380 5/20 (25%)
leucine-rich repeat 652..672 CDD:275380 6/19 (32%)
LRR_8 698..765 CDD:290566 19/69 (28%)
leucine-rich repeat 700..726 CDD:275380 10/28 (36%)
leucine-rich repeat 727..745 CDD:275380 6/17 (35%)
LRR_8 777..839 CDD:290566 11/61 (18%)
leucine-rich repeat 779..802 CDD:275380 2/22 (9%)
leucine-rich repeat 829..852 CDD:275380 3/22 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR45617
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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