Protein Alignment CG5819 and igfals

DIOPT Version :9

• Sequence 1: NP_001246458.1
• Gene: CG5819 / 37547
• FlyBaseID: FBgn0034717
• Length: 915
• Species: Drosophila melanogaster
• Sequence 2: XP_002940278.2
• Gene: igfals / 100489984
• XenbaseID: XB-GENE-1008441
• Length: 601
• Species: Xenopus tropicalis
• Alignment Length: 603
• Identity: 150/603 - (24%)
• Similarity: 241/603 - (39%)
• Gaps: 120/603 - (19%)

  Fly     4 VLELALLVLGVIS----SCRAVNCPWPCRCTWVVDSLYA-DCSRRSLQTYPNFDGIPVEHLDLSG 63
            ||...:||.|.:.    |.....||.||.|::.....|: .||.|:|...|.........|.|.|
 Frog    12 VLVWNILVCGSLEAEPRSPEPAPCPPPCVCSYDYSEEYSVFCSSRNLTRVPEPPPPAARSLWLDG 76

  Fly    64 NKFLEFPT-LYADIDSLIYLDLSSNYISSIGAKTLIGFTSLRTLLLANNSIDSWESLSPNEAFKY 127
            |....... .:.::..|.:|:|.|:.::|:..:.|.|..:|..|.|..|.|   :||:|: .|.:
 Frog    77 NNLTTVQAGAFRNLSHLDFLNLQSSQVASLEQQALHGLKALAHLHLERNMI---KSLAPS-TFTH 137

  Fly   128 APSLKRLGLDGNRLGSFGNGESFELLTSSSLTDLGLSSCGISSIG-------GDQMVNQLPNLER 185
            ..:|..|.|:.|.|....:|     |.|      |||:....::|       .|.:.:.|.||..
 Frog   138 TQNLVSLTLNNNFLTKIEDG-----LFS------GLSNLWYLNLGWNLLVVLPDMVFHDLLNLRE 191

  Fly   186 LNLANNQLAQIAA---LPSRTLRVLDLSNCSIKNLSGFFLDAMQNLEALNLSRN-----TELQFD 242
            |.||.|:|..:..   |....|:.||||..|:|.:........|....|.|:.|     ....|.
 Frog   192 LVLAGNRLVYLQPSLFLSLGELKELDLSGNSLKGIKANVFTRQQKTHKLYLNHNHISTVAPRAFS 256

  Fly   243 SLSEDPILTYMLRKLDVSYCNLDSI---ELSGLPQLTEVRLQGNLLRVVDVNTFANNSMLEVVDL 304
            .:..       ||.||:|:..|.::   ...|||.|..:||..|.|..:....|.:...|..::|
 Frog   257 GMKN-------LRWLDLSHNRLTALYEDTFFGLPSLNVLRLSNNSLTSLRPRIFKDLQFLVELNL 314

  Fly   305 SQNVLRHIGQDAFAKLKRLKELNLAFNEIARL-DRNFIRNNDVLVELNLSRNVLQKLT------- 361
            .||.::.:.:..|..|.:|:.|:|..|.:..: ..:|:...:|.| :|||.|.|:.|.
 Frog   315 GQNKIKILLERTFEGLAQLELLSLNHNNVQEIRPGSFLGLLNVAV-INLSGNCLKSLAEHCFKGL 378

  Fly   362 -KIVS-------------------NSVRTINMSWCEITSIESTALSSLSVIQKLDLSNNLITDMP 406
             |:.|                   :|:|.:.:...||.:||..:.:.|..:.:|||.:|.:|.:.
 Frog   379 GKLHSLHMESSCLSHIKPQMFAGLSSIRRLFLQNNEIVAIEDHSFTDLHGLLELDLRSNKLTHLT 443

  Fly   407 T--FMRSETLQQLNLANCRLTTVRNNTFREFPELADLHLNGNRLTS------------------- 450
            |  |...:.|..|.|::.::.|:....|....:|..|.|:.|:|.:
 Frog   444 TRSFTGLKNLSYLLLSSNQILTISPEVFSPVQQLQWLDLSDNQLKALTEDIFLPLSSLRYLSLKN 508

  Fly   451 ----PIPPNYFDGNKFLDQLWLGDNPWICDC-----------HSPLFVDFYDYL-----TAKPAK 495
                .|..|:......:.||||..|.|.|.|           :|.:.......:     ||.|.
 Frog   509 NCLKTISVNFLIPPPTMQQLWLNGNQWDCGCALKGLRDLALRNSTIVPHLVQSISEGDDTASPV- 572

  Fly   496 IKDRNHLRCAAPAVFYGK 513
               .|::.||:|....|:
 Frog   573 ---YNNITCASPPEAMGQ 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5819	NP_001246458.1	leucine-rich repeat	56..78	CDD:275380	4/22 (18%)
		LRR_RI	<58..236	CDD:238064	52/188 (28%)
		LRR_8	78..141	CDD:290566	20/62 (32%)
		leucine-rich repeat	79..102	CDD:275380	7/22 (32%)
		leucine-rich repeat	103..130	CDD:275380	9/26 (35%)
		leucine-rich repeat	131..155	CDD:275380	7/23 (30%)
		LRR_8	156..214	CDD:290566	19/67 (28%)
		leucine-rich repeat	158..182	CDD:275380	6/30 (20%)
		LRR_8	202..285	CDD:290566	25/90 (28%)
		leucine-rich repeat	204..227	CDD:275380	7/22 (32%)
		leucine-rich repeat	254..274	CDD:275380	8/22 (36%)
		LRR_8	273..333	CDD:290566	17/59 (29%)
		leucine-rich repeat	275..298	CDD:275380	6/22 (27%)
		LRR_RI	277..>471	CDD:238064	56/246 (23%)
		leucine-rich repeat	299..322	CDD:275380	6/22 (27%)
		LRR_8	321..402	CDD:290566	26/108 (24%)
		leucine-rich repeat	323..346	CDD:275380	5/23 (22%)
		leucine-rich repeat	347..391	CDD:275380	16/70 (23%)
		leucine-rich repeat	392..413	CDD:275380	7/22 (32%)
		LRR_8	393..448	CDD:290566	16/56 (29%)
		leucine-rich repeat	414..437	CDD:275380	5/22 (23%)
		LRRCT	471..517	CDD:214507	13/59 (22%)
igfals	XP_002940278.2	leucine-rich repeat	69..92	CDD:275380	4/22 (18%)
		PLN00113	71..>534	CDD:215061	120/485 (25%)
		leucine-rich repeat	93..116	CDD:275380	7/22 (32%)
		leucine-rich repeat	117..140	CDD:275380	9/26 (35%)
		leucine-rich repeat	141..164	CDD:275380	10/33 (30%)
		leucine-rich repeat	165..188	CDD:275380	3/22 (14%)
		leucine-rich repeat	189..212	CDD:275380	7/22 (32%)
		leucine-rich repeat	213..236	CDD:275380	7/22 (32%)
		leucine-rich repeat	237..260	CDD:275380	4/22 (18%)
		leucine-rich repeat	261..284	CDD:275380	8/22 (36%)
		leucine-rich repeat	285..308	CDD:275380	6/22 (27%)
		leucine-rich repeat	309..332	CDD:275380	6/22 (27%)
		leucine-rich repeat	333..354	CDD:275380	5/20 (25%)
		leucine-rich repeat	357..380	CDD:275380	8/23 (35%)
		leucine-rich repeat	381..404	CDD:275380	1/22 (5%)
		leucine-rich repeat	405..428	CDD:275380	6/22 (27%)
		leucine-rich repeat	429..450	CDD:275380	7/20 (35%)
		leucine-rich repeat	453..472	CDD:275380	4/18 (22%)
		leucine-rich repeat	477..500	CDD:275380	5/22 (23%)
		leucine-rich repeat	525..537	CDD:275378	6/11 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910