Protein Alignment dve and SATB1

DIOPT Version :9

• Sequence 1: NP_477242.1
• Gene: dve / 37546
• FlyBaseID: FBgn0020307
• Length: 1024
• Species: Drosophila melanogaster
• Sequence 2: NP_001182399.1
• Gene: SATB1 / 6304
• HGNCID: 10541
• Length: 795
• Species: Homo sapiens
• Alignment Length: 986
• Identity: 192/986 - (19%)
• Similarity: 332/986 - (33%)
• Gaps: 325/986 - (32%)

  Fly   131 HQQQAQQAGAGVGSGELAGRRSSEGTPPTAHPPTNSEGQALSSSTASSSQNATPKSDRERERERE 195
            |..:|.|   |....|::...|....||              :..|...||.:|
Human     3 HLNEATQ---GKEHSEMSNNVSDPKGPP--------------AKIARLEQNGSP----------- 39

  Fly   196 RDREERVERGSISCLPPAALGMAVGVQQAQHQEKLLSHPALDSRREFDVSKVNPKS---LPLHCV 257
                  :.||.:            |...|:.|...|.|..       .:.|.|.:.   ||:.||
Human    40 ------LGRGRL------------GSTGAKMQGVPLKHSG-------HLMKTNLRKGTMLPVFCV 79

  Fly   258 VESVHSLHASLTIDTRQPWKRRPNIETDSYVIIAAATPWSEIVQTALQRLGYSQEVANTARGSLI 322
            ||...:   ::..|.::        |...:|::.....::::::.||..||||...|..|:|.:.
Human    80 VEHYEN---AIEYDCKE--------EHAEFVLVRKDMLFNQLIEMALLSLGYSHSSAAQAKGLIQ 133

  Fly   323 IKHWKPIPLEQISDNPAVPVSDIVGELTSVITLRIVI--------LRPKTSPFGEIKDKLLKLLV 379
            :..|.|:||..::|.|...|:|::.::..|:||:|.:        |.|:......:::.|..||.
Human   134 VGKWNPVPLSYVTDAPDATVADMLQDVYHVVTLKIQLHSCPKLEDLPPEQWSHTTVRNALKDLLK 198

  Fly   380 LQSHAVLRSTGCPLDEVTLSQICRSSHQNTYALPGGEISDELRRKFDQWWSNQLSPQATAMTPKM 444
            ..:.:.| :..|||.:..:|.|..|::   ||    .:|....::|.:|:.:      ...|..|
Human   199 DMNQSSL-AKECPLSQSMISSIVNSTY---YA----NVSAAKCQEFGRWYKH------FKKTKDM 249

  Fly   445 LPFMTGPSAVPVPVAVPGEMDFPVGTAMAAAAAAAAHAAAAGGAAGGNPLGSMGSRESLLLANEA 509
            :.                |||                              |:..     |:.:.
Human   250 MV----------------EMD------------------------------SLSE-----LSQQG 263

  Fly   510 AHHAGAGQAPGPGHHGSMLVHPMHASMHHHHHHGGGGGHGPPYPN-QKTRMRTSFDPEMELPK-- 571
            |:|...||.|.||:.......|...|      ||.......|.|| ....:.|...|::...:
Human   264 ANHVNFGQQPVPGNTAEQPPSPAQLS------HGSQPSVRTPLPNLHPGLVSTPISPQLVNQQLV 322

  Fly   572 ----LQKWFADNPHPSRQQIQTYVVQLNALESRRGRKPL--------DVNNVVY-WFKNARAAQK 623
                |.:.:|.|...::|.:....:......||...|||        :|::.:| |.
Human   323 MAQLLNQQYAVNRLLAQQSLNQQYLNHPPPVSRSMNKPLEQQVSTNTEVSSEIYQWV-------- 379

  Fly   624 RAEMRGGSLGSAISALGHAAMN---GYLSQHAPLGQNSSSSAGSQPMSMGNLSMSHDYLKSPLSL 685
            |.|::...:..|:.|  ..|.|   |.||:  .|.:.......||.: :.||....::|:.|
Human   380 RDELKRAGISQAVFA--RVAFNRTQGLLSE--ILRKEEDPKTASQSL-LVNLRAMQNFLQLP--- 436

  Fly   686 KSEDIDTMSQHSDDMDEEQSRPNTPQ----LPLSLTTHERHRSSPLMDEDEDEAGEQQQPQEAKS 746
             ..:.|.:.|     ||.:...|...    .||..|...|    |...:....|.|:....|..:
Human   437 -EAERDRIYQ-----DERERSLNAASAMGPAPLISTPPSR----PPQVKTATIATERNGKPENNT 491

  Fly   747 DGMNGSVKDEERQEKSRDELQD-------------------NEKENSNGEDRHL----------- 781
            ..:|.|:.||.:||..|.::..                   ..||:.:.|:|.|
Human   492 MNINASIYDEIQQEMKRAKVSQALFAKVAATKSQGWLCELLRWKEDPSPENRTLWENLSMIRRFL 556

  Fly   782 -----DADAQMEASSNLNNNHNNSS---LHIEQEVGSTPKRSTPKEEDDDLDMDEDEEDNENDAS 838
                 :.||..|..||..::|.:..   :|:..|...:|..:|..:             .|:...
Human   557 SLPQPERDAIYEQESNAVHHHGDRPPHIIHVPAEQIQSPSPTTLGK-------------GESRGV 608

  Fly   839 HLDEFRSPSPDLAGGVVP-----------HKDQLPFPMVPNSMFSQSFMYMSHYIPAFGQAAAGH 892
            .|....:|:|.|  |..|           .:.|.|.|..|...            |..|...
Human   609 FLPGLPTPAPWL--GAAPQQQQQQQQQQQQQQQAPPPPQPQQQ------------PQTGPRL--- 656

  Fly   893 PHHHAAAAAAAAGIQPNALMGGGGLNLSSISNEERRKRNRTFIDPVTEVPKLEQWFAMNTHPSHN 957
            |......|:.|.                  |:||.|::.|    |.|::          :..:..
Human   657 PPRQPTVASPAE------------------SDEENRQKTR----PRTKI----------SVEALG 689

  Fly   958 LILKYTEDLNTMPYRQKFPRLESK------NVQFWFKNRRAKCK---RLKMSLYDSNQCAQLGGL 1013
            ::..:.:|:...|..:....|.::      .:..:|:|:|...|   :||    |::      ||
Human   690 ILQSFIQDVGLYPDEEAIQTLSAQLDLPKYTIIKFFQNQRYYLKHHGKLK----DNS------GL 744

  Fly  1014 GSFVPKYEERD 1024
            ...|.:|:|.:
Human   745 EVDVAEYKEEE 755

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dve	NP_477242.1	SATB1_N	252..358	CDD:211426	29/105 (28%)
		HOX	556..623	CDD:197696	14/81 (17%)
		PPP4R2	<644..778	CDD:286293	33/159 (21%)
		HOX	928..995	CDD:197696	10/72 (14%)
SATB1	NP_001182399.1	ULD	72..170	CDD:406838	30/108 (28%)
		CUTL	176..246	CDD:406861	17/83 (20%)
		CUT	372..444	CDD:396794	19/88 (22%)
		CUT	497..567	CDD:396794	13/69 (19%)
		HOX	676..733	CDD:197696	9/70 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159379
Domainoid	1	1.000	64	1.000	Domainoid score	I10126
eggNOG	1	0.900	-	-		E1_KOG3755
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7927
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm40416
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4065
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.810