Protein Alignment Oatp58Dc and Slco1a6

DIOPT Version :9

• Sequence 1: NP_001097409.1
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_570092.1
• Gene: Slco1a6 / 84608
• RGDID: 69304
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 709
• Identity: 183/709 - (25%)
• Similarity: 300/709 - (42%)
• Gaps: 137/709 - (19%)

  Fly   125 SMTYAYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRPRWIGFGLLTIVF 189
            :::..|.|..:|.||:||.|.:...|:|:...::...|:...::|:..|.|||..||.|...:..
  Rat    34 ALSATYMNSMLTQIERRFNISTSIVGLINGSFEVGNLLLIIFVSYFGRKRHRPIMIGIGCAVMGL 98

  Fly   190 FCILTTAPHFLYGPGEDALALTSEFGGMPDENATMEAI--EEQRSKTLCRLNGGGAECEVGEGNF 252
            .|.:.:.||||.|..|....::      |..|.:..:.  .|.|::|| :.....||| |.|...
  Rat    99 GCFIISLPHFLMGRYEYETTIS------PTSNLSSNSFLCMENRTQTL-KPTQDPAEC-VKEMKS 155

  Fly   253 APQLLLFVAQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAIGYALASFCLRL 317
            ...:.:.|...|.|||.:....||:||::|..|...:|..:.:....::.||.....|.|||..:
  Rat   156 LMWIYVLVGNIIRGIGETPIMPLGISYIEDFAKSENSPFYIGILEVGKITGPIAAIWLGSFCATI 220

  Fly   318 YIAPQMHPV------INNKDPRWLGAWWLGWLVMGGLLSFSGV----FLSMFPKELPRAVAR--R 370
            |:  .|..|      |...|.|.:||||:|:||..||.....:    |...||||.|..:|.  :
  Rat   221 YV--DMGSVNTDDLTITPTDTRCVGAWWIGFLVCAGLNILISIPFFFFPKTFPKEGPEDMANETK 283

  Fly   371 KVEENRRREKERLSVKSTEKERLTAELDQKTTAEAKASFQDMLKTFRRLITNKTYMCNTLSSIFY 435
            ..|.::.|||.:     .||..:|               :|.....:.|..|..||...|:|:..
  Rat   284 NDEGDKHREKAK-----EEKRGIT---------------KDFFLFMKSLSCNPIYMLCVLTSVLQ 328

  Fly   436 LVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISRYKPRARYMAAWNVI 500
            :.|:...:.|.|||:|..|.:|::.:..:.|...|....||.|:||||:.::|..
  Rat   329 VNGFVSIFTFKPKYLEHHYGKSSSEAIFLMGLYTLPSVCVGYLISGFIMKKFKIT---------- 383

  Fly   501 VGFLTVAGILAYAFIGCPGNESSVI------VNIHDSSLAGNTTT-----------------CNS 542
               |..|..::|    |.|....::      :...:..:||.||:                 ||:
  Rat   384 ---LKKAAFISY----CLGMSECLLSLCNFMLTCDNVPIAGLTTSYEGIQQSFDMENTVLADCNT 441

  Fly   543 ACSCDYVRYSPVCGENNMTYISACHAGCKKLLVNSEGKKIFYDCSCIPSDDAGNSTSQFKRLTSF 607
            .|||....:.||||:|.:.||:.|.|||:| .|.|....:..|||||.|  :|||:
  Rat   442 RCSCLTKTWDPVCGDNGLAYITPCLAGCEK-SVGSGINMVLQDCSCIQS--SGNSS--------- 494

  Fly   608 DLSNDEVSQNTSVHSQLEALANGQAMPGAC---PVNCWTQFVAFLAVMCCLKFVGASGRASNFLV 669
                                    |:.|.|   | :|..:...||.:.....|..:......:::
  Rat   495 ------------------------AVLGLCNKGP-DCANKLQYFLIITVFCSFFYSLSLIPGYMI 534

  Fly   670 SVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWG-KTCTNKGNCWLYDPLSMRY 733
            .:||:..::|:..:|.......:|..|.:||:||.:.||.||.|| :.|...|.|..|:
  Rat   535 FLRCMKSEEKSLGIGLQAFCMRILGGILAPIYFGVLIDRTCLHWGTQKCGEPGACRTYE------ 593

  Fly   734 TLNFTAAVFIAIGAIFD----LGVWYYAKDLKIFDEDVKEVEMKIVQHEEEANNEKNTE 788
             :|...::::.:.|...    |..::..:.::.| :...::...:..|.|....||.:|
  Rat   594 -INSFRSIYLGLPAALRGSSYLPAFFILRLMRKF-QFPGDINSPVTDHVEMMLTEKESE 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_001097409.1	OATP	112..731	CDD:281175	174/646 (27%)
		MFS	114..>518	CDD:119392	112/406 (28%)
		KAZAL_SLC21	537..590	CDD:238650	25/69 (36%)
Slco1a6	NP_570092.1	oat	1..625	CDD:273279	177/681 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..295		5/18 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	647..670		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820