Protein Alignment Oatp58Dc and Slco1a3

DIOPT Version :9

• Sequence 1: NP_001097409.1
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_110464.2
• Gene: Slco1a3 / 80899
• RGDID: 621387
• Length: 670
• Species: Rattus norvegicus
• Alignment Length: 721
• Identity: 197/721 - (27%)
• Similarity: 309/721 - (42%)
• Gaps: 139/721 - (19%)

  Fly   121 GC-------IFSMTYAY----FNGT-----ITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAY 169
            ||       :.::|.||    .:||     :|.||::|.||:...|.|:...:|...|:...::|
  Rat    14 GCFAKIKVFLMALTCAYVSKSLSGTFMSSMLTQIERQFGIPTAIVGFINGSFEIGNLLLIIFVSY 78

  Fly   170 YAGKGHRPRWIGFGLLTIVFFCILTTAPHFLYGPGEDALALTSEFGGMPDENATMEAI--EEQRS 232
            :..|.|||..||.|...:...|.:.:.||||.|..|....:      :|..|.:..:.  .|.::
  Rat    79 FGMKLHRPIVIGVGCAVMGLGCFIISLPHFLMGRYEYETTI------LPTSNLSSNSFLCMENQT 137

  Fly   233 KTLCRLNGGGAECEVGEGNFAPQLLLFVAQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSY 297
            :||.... ..||| |.|......:.:.|...|.|||.:....|||||:::..|...:|..:.:..
  Rat   138 QTLNPAQ-DPAEC-VKEVKSLMWIYVLVGNIIRGIGETPIMPLGVSYIENFAKSENSPLYIGILE 200

  Fly   298 FLRMLGPAIGYALASFCLRLYI----APQMHPVINNKDPRWLGAWWLGWLVMGGLLSFSGVFLSM 358
            ..:|:||..|..|.|||..:|:    .......|...|.||:||||:|:||..|:.....:....
  Rat   201 TGKMIGPIFGLLLGSFCASIYVDTGSVNTDDLTITPTDIRWVGAWWIGFLVCAGVNILISIPFFF 265

  Fly   359 FPKELPRAVARRKVE--ENRRREKERLSVKSTEKERLTAELDQKTTAEAKASFQDMLKTFRRLIT 421
            |||.||:...:..|:  ||.:.||.|...|. ||..:|               :|.....:.|..
  Rat   266 FPKTLPKEGLQENVDGTENAKEEKHREKAKE-EKRGIT---------------KDFFPFLKSLSC 314

  Fly   422 NKTYMCNTLSSIFYLVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISR 486
            |..||..||.|:..:..:..|:.|.|||:|.||.:|.|....:.|...|....:|.|::||::.:
  Rat   315 NPIYMLFTLISVLQVNAFNIYFSFLPKYLENQYGKSTAEVIFLMGVYNLPAICIGYLIAGFMMKK 379

  Fly   487 YKPRARYMAAWNVIVGFLTVA-GILAYAFIGCPGNESSVIVNIHDSSLAGNTTT----------- 539
            :|...:..|       ||... .:..|:|..|     :.::...:..:||.|.:
  Rat   380 FKITVKTAA-------FLAFCLSLSEYSFGFC-----NFLITCDNVPVAGLTNSYERDQKPLYLE 432

  Fly   540 ------CNSACSCDYVRYSPVCGENNMTYISACHAGCKKLLVNSEGKKIFYDCSCIPSDDAGNST 598
                  ||:.|||....:.||||:|.:.|:|||.|||:| .|.:....:|::||||.|  .|||:
  Rat   433 NNVLADCNTRCSCLTKTWDPVCGDNGLAYMSACLAGCEK-SVGTGTNMVFHNCSCIQS--PGNSS 494

  Fly   599 SQFKRLTSFDLSNDEVSQNTSVHSQLEALANGQAMPGAC---PVNCWTQFVAFLAVMCCLKFVGA 660
                                             |:.|.|   | .|..:....|.:...|..:.:
  Rat   495 ---------------------------------AVLGLCNKGP-ECTNKLQYLLILSGFLSILYS 525

  Fly   661 SGRASNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWG-KTCTNKGNCW 724
            ......::|.:||:..::|:..:|.......:.|.||:||:||.:.||.||.|| :.|...|.|.
  Rat   526 FAAIPGYMVFLRCIKSEEKSLGIGIHAFCIRVFAGIPAPIYFGALIDRTCLHWGTQKCGAPGACR 590

  Fly   725 LYDPLSM-RYTLNFTAA----------VFIAIGAIFDL-GVWYYAKDLKIFDEDVKEVEMKIVQH 777
            :||..|. |..|..:||          |.:.:...|.| |        ||...:::..|||:.:.
  Rat   591 MYDINSFRRIYLGMSAALRGSSYLPAFVIVILTRKFSLPG--------KINSSEMEIAEMKLTEK 647

  Fly   778 EEEANN 783
            |.:..:
  Rat   648 ESQCTD 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_001097409.1	OATP	112..731	CDD:281175	182/655 (28%)
		MFS	114..>518	CDD:119392	120/421 (29%)
		KAZAL_SLC21	537..590	CDD:238650	24/69 (35%)
Slco1a3	NP_110464.2	oat	1..625	CDD:273279	188/683 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820