Protein Alignment Oatp58Dc and slco1f4

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001074135.2
• Gene: slco1f4 / 791184
• ZFINID: ZDB-GENE-070112-2172
• Length: 644
• Species: Danio rerio
• Alignment Length: 646
• Identity: 189/646 - (29%)
• Similarity: 294/646 - (45%)
• Gaps: 117/646 - (18%)

  Fly   125 SMTYAYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRPRWIGFGLLTIVF 189
            |||.:|...|||.|||||:|||...|.|....::...||..:::|...|.|||:.||.|:|.:..
Zfish    41 SMTGSYTKSTITQIEKRFEIPSSTVGFIDGSFEMGNMLVITLVSYIGAKFHRPKIIGAGVLLMGI 105

  Fly   190 FCILTTAPHFLYGPGE--DALALTSEFGGMPDENATMEAIEEQRSKTLCRLNGGGAECEVGEGNF 252
            ..:|..:||||.|..:  .|...|::.|..    ..:........:||.:...|   |:..|...
Zfish   106 GTLLMASPHFLMGRYKYGTAATHTNDAGNF----TVISTCSSDSQETLQQPFSG---CQKEEAES 163

  Fly   253 AP-QLLLFVAQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAIGYALASFCLR 316
            :| .:::.:...:.|||.:....||:|::||..:...:...:.....|:.:||..||.|.|.|..
Zfish   164 SPFWVIVVLGNTMRGIGEASIVPLGMSFIDDYARPENSAFYIGCLNTLKGIGPIFGYMLGSLCAN 228

  Fly   317 LYI----APQMHPVINNKDPRWLGAWWLGWLVMGGLLSFSGVFLSMF-PKELPRAVARRKVEENR 376
            ||:    ..|....|..:|.||:||||||: |:.|||:....|...| ||.||
Zfish   229 LYVDFGLVDQESVTITPQDSRWVGAWWLGY-VVSGLLTLLAAFPFWFLPKVLP------------ 280

  Fly   377 RREKERLSVKSTEKERLTAELDQKTTAEAKASFQDMLKTFRRLITNKTYMCNTLSSIFYLVGYTP 441
              |..::|:.....::      .|||.......:|...||:||:|||.|:   |...:.:|.:..
Zfish   281 --ENSQISLLDNTPQQ------HKTTPSLTEIVKDFAPTFKRLLTNKIYI---LYLAYSIVAFND 334

  Fly   442 YWI---FTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISRYKPRARYMAAWNVI--- 500
            :.|   :||||:|.|:.|||:.::.:.|..::...|:||.|||.::.|:|        |.::
Zfish   335 FAIVATYTPKYLEQQFGQSASKANFLIGVTSIPAVALGVFLSGLMMKRFK--------WGLLASA 391

  Fly   501 -VGFLTVAGILAYAFIGCPGNESSVIVNIHDSSLAGNTT-----------------TCNSACSCD 547
             |..||   |:|..|:..|    ...::..:..:||.|.                 :||:.|.|.
Zfish   392 RVNLLT---IVATVFLAVP----FFALSCENLDIAGVTVPYQGSTEVQGVTSDVLPSCNADCGCP 449

  Fly   548 YVRYSPVCGENNMTYISACHAGCKKLLVNSEGKKI-FYDCSCIPSDDAGNSTSQFKRLTSFDLSN 611
            .:::.||||||.:||||.|||||..  ....|:.: |:||.||               .|:.||
Zfish   450 DLQWDPVCGENGVTYISPCHAGCNS--TQGAGRNMTFHDCRCI---------------QSWGLS- 496

  Fly   612 DEVSQNTSVHSQLEALANGQAMPGAC--PVNCWTQFVAFLAVMCCLKFVGASGRASNFLVSVRCV 674
                           :.|..|:.|.|  ...|......:|.:.....|:...|....|.:|:|.|
Zfish   497 ---------------VGNSSAVLGQCSRDPKCNRMIYIYLGLQSLAFFLCGLGIIPFFTMSLRIV 546

  Fly   675 PEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWG--KTCTNKGNCWLYDPLSMRY 733
            ..:.|:.::|..:....:|..||:||:||.:.|..||.||  |:| .:|.|.:||..:.|:
Zfish   547 DPELKSLSVGMLLLAVRVLGGIPAPIYFGALIDSTCLKWGQNKSC-GRGACRIYDIETFRF 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	188/642 (29%)
slco1f4	NP_001074135.2	MFS	26..544	CDD:475125	166/581 (29%)