Protein Alignment Oatp58Dc and slco1b3

DIOPT Version :9

• Sequence 1: NP_001097409.1
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_031753845.1
• Gene: slco1b3 / 613085
• XenbaseID: XB-GENE-5943217
• Length: 690
• Species: Xenopus tropicalis
• Alignment Length: 642
• Identity: 199/642 - (30%)
• Similarity: 294/642 - (45%)
• Gaps: 100/642 - (15%)

  Fly   129 AYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRPRWIGFGLLTIVFFCIL 193
            :|...:||.||:||.|.|...|:|....:|...:|.|:::|:..:.||||.|..|.:.:.....|
 Frog    59 SYMKSSITQIERRFDISSSTVGMIDGSFEIGNLMVIAIVSYFGAQFHRPRIIAAGCILMSLGSFL 123

  Fly   194 TTAPHFLYGPGEDALALTSEFGGMP--DENATMEAIEEQRSKTLCRLNGGGAECEVGEGNFAPQL 256
            |..|||..|     |......||..  :.|||:.......:::|  ::....:| |.|......:
 Frog   124 TAMPHFFMG-----LYKYETVGGPTSLNSNATINVSPCLANRSL--VDTPKPDC-VTENGSHMWV 180

  Fly   257 LLFVAQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAIGYALASFCLRLY--- 318
            .|.|...:.|||.:....||:||:||.::...||..::..:.:.|.||..|:.|.||..|||
 Frog   181 FLLVGNILRGIGETPIAPLGISYLDDFSRPENTPLHIACLHTVAMFGPMTGFMLGSFLARLYVDI 245

  Fly   319 ---------IAPQMHPVINNKDPRWLGAWWLGWLVMGGLLSFSGVFLSMFPKELPRAVARRKVEE 374
                     |.||        |.||:||||:|:|:.|.:...|.:.....|:.|..  .:|:.::
 Frog   246 GFVDTDTITITPQ--------DTRWVGAWWIGFLLSGAVNLMSAIPFFFLPESLKE--EQREGQK 300

  Fly   375 NRRREKERLSVKSTEKERLTAELDQKTTAEAKASFQDMLKT--FRRLITNKTYMCNTLSSIFYLV 437
            .:.::.|....|..||..|             ..|...|||  |.||..  ..||.||......:
 Frog   301 PQTKQGEEKGHKQKEKPTL-------------RGFFAALKTLCFNRLFV--MLMCLTLLQTNSFL 350

  Fly   438 GYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISRYK---PRARYMAAWNV 499
            |:..|   .|||:|.||.||.:.::.|||...|..:|:|:.|.|.|:.|||   ..|..||....
 Frog   351 GFITY---KPKYMEQQYGQSISKANFVTGVSTLPAAALGMFLGGLIMKRYKFGLLGASKMAYGTS 412

  Fly   500 IVGFLTVAGILAYAFIGCPGNESSVIVNIHDSSLAGN------TTTCNSACSCDYVRYSPVCGEN 558
            ::.||.   .|:..||||..|..:.|...:|.....|      .:.|||.|.|...::.||||||
 Frog   413 LLAFLL---SLSAFFIGCENNNVAGITVTYDRVKVNNFQDRIIYSPCNSDCHCSSKQWDPVCGEN 474

  Fly   559 NMTYISACHAGCKKLLVNSEGKKIFYDCSCIPSDDAGNSTSQFKRLTSFDLSNDEVSQNTSVHSQ 623
            .:||:|||.||||....:..| .::::||||   |...||                :.|:|.|.
 Frog   475 GVTYVSACLAGCKASTGSGLG-TVYHNCSCI---DTALST----------------AVNSSAHL- 518

  Fly   624 LEALANGQAMPGACP--VNCWTQFVAFLAVMCCLKFVGASGRASNFLVSVRCVPEKDKTAAMGFG 686
                       |:||  .:|...|:.::.......|:.|.|.:|.:::.:..|..:.|:.|:|..
 Frog   519 -----------GSCPRGPDCSRMFMFYVVTQAINTFIFALGASSAYVLLLWSVNPEMKSLAVGVY 572

  Fly   687 MTLCSMLAFIPSPIFFGWVFDRVCLVWG-KTCTNKGNCWLYDPLSMRYT-LNFTAAV 741
            |.|...||.||:||:||.:.|:.||.|| :.|..:|.|.|||..|.|.. |..||.:
 Frog   573 MLLIRTLAGIPAPIYFGAIIDKSCLKWGTRLCGGRGACRLYDADSFRRRFLGLTAGI 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_001097409.1	OATP	112..731	CDD:281175	194/629 (31%)
		MFS	114..>518	CDD:119392	124/407 (30%)
		KAZAL_SLC21	537..590	CDD:238650	24/52 (46%)
slco1b3	XP_031753845.1	MFS_SLCO1B_OATP1B	40..558	CDD:341015	169/569 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010