Protein Alignment Oatp58Dc and slco3a1b

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_699020.3
• Gene: slco3a1b / 570448
• ZFINID: ZDB-GENE-161017-34
• Length: 690
• Species: Danio rerio
• Alignment Length: 720
• Identity: 192/720 - (26%)
• Similarity: 300/720 - (41%)
• Gaps: 144/720 - (20%)

  Fly    89 EKNVTCGFWIFKGTFYQRFAN-------QTAYVLLYGIVGCIFSMTYAYFNGTITTIEKRFKIPS 146
            :|..:|            |:|       :.|.:|..|.||       ||....:||:|:||.:.|
Zfish    16 QKKTSC------------FSNIKIFLISECALMLAQGTVG-------AYLVSVLTTLERRFNLQS 61

  Fly   147 KNTGIISVGNDISQTLVSAVLAYYAGKGHRPRWIGFGLLTIVFFCILTTAPHFL----------- 200
            .:.|:|:...:|....:...::|:..:.||||.||.|.:.:....:|:..|.||
Zfish    62 ADVGVIASSFEIGNLALILFVSYFGARAHRPRLIGCGGIVMALGALLSALPEFLTHQYQYQTGES 126

  Fly   201 --YGPGEDALALTSEFGGMPDENATMEAIEEQRSKTLCRLNGGGAECEVGEGNFAPQLLLFVAQF 263
              .|.|::..:.:|..|                      |:..|..|..........|||..||.
Zfish   127 RPVGQGQNVCSNSSRAG----------------------LSDPGYICGNRTNTNMMYLLLIGAQM 169

  Fly   264 ISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAIGYALASFCLRLYIAPQMHPV-- 326
            :.|:|.:....|||||:||:.::..:...:.:.:...:.|||.|:.|.|.|.::|:.......
Zfish   170 LLGVGATPLQPLGVSYIDDHVRREDSSLYIGILFSTLVFGPACGFILGSLCTKVYVDAVFIDTTT 234

  Fly   327 --INNKDPRWLGAWWLGWLVMGGLLSFSGVFLSMFPKELPRAVARRKVEENRRREKERLSVKSTE 389
              |...||||:||||.|:::.|..|..|..|:..||:.|              .|........:|
Zfish   235 LDITPDDPRWIGAWWGGFIICGLFLFVSSFFMFGFPQSL--------------NEPGEGPGGESE 285

  Fly   390 KERLTAELDQ-----KTTAEAKAS--------FQDMLKTFRRLITNKTYMCNTLSSIFYLVGYTP 441
            :..|.|||.|     ||:.:.:.|        .|.:.|..:.|::|..:.|..|::...:.....
Zfish   286 QAMLPAELVQEYEGVKTSDDLEISTGLTCCQHLQVIPKVTKHLLSNPVFTCVILAACMEIAVVAG 350

  Fly   442 YWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISRYKPRARYMAAWNVIVGFLTV 506
            :..|..||:|.|:..|.::::.:.|..|:..:.:|:.|.|.::.:....|.......:||..::.
Zfish   351 FAAFLGKYLEQQFNLSTSSANQLLGMTAIPCACLGIFLGGLLVKKLDLSALGAIRLAMIVNIIST 415

  Fly   507 AGILAYAFIGC-PGNESSVIVNIHDSSLAG---NTTTCNSACSCDYVRYSPVCGENNMTYISACH 567
            |..:::.|:|| .|..:.|.|...:.||..   ....|.|.|:|.....|||||.|.:||:|||.
Zfish   416 ACYVSFLFLGCDTGPVAGVTVAYGNESLGSWERTEAACLSGCNCYKSSLSPVCGSNGVTYLSACL 480

  Fly   568 AGCKKLLVNSEGKKIFYDCSCIPSDDAGNSTSQFKRLTSFDLSNDEVSQNTSVHSQLEALANGQA 632
            |||.:  .|..|      |.||                              .||  |.|  |.|
Zfish   481 AGCTR--TNLTG------CKCI------------------------------AHS--EGL--GTA 503

  Fly   633 MPGACP-VNCWTQFVAFLAVMCCLKFVGASGRASNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFI 696
            .||.|| ..|...|:.||||:|....:||..:..:.::.:|.|..:.|:.|:|....|..:|.||
Zfish   504 TPGKCPSPGCQQAFLTFLAVVCACSMIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFI 568

  Fly   697 PSPIFFGWVFDRVCLVWGKTCTNKGNCWLYDPLSMRYTLNFTAAVFIAIGAIFDLGVWY-----Y 756
            |.|:.||...|..||:|...|..||.|.|||.::.||.....|.|..:...|.....|.     |
Zfish   569 PPPLIFGIGIDSTCLLWSSMCGIKGACMLYDNVTYRYLYVSIAIVLKSSAFILYAVTWQCLRHNY 633

  Fly   757 AKDLK 761
            .|.:|
Zfish   634 CKYIK 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	178/652 (27%)
slco3a1b	XP_699020.3	MFS	25..544	CDD:475125	155/603 (26%)