Protein Alignment Oatp58Dc and slco5a1a

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_073776477.1
• Gene: slco5a1a / 570033
• ZFINID: ZDB-GENE-090316-1
• Length: 819
• Species: Danio rerio
• Alignment Length: 666
• Identity: 203/666 - (30%)
• Similarity: 323/666 - (48%)
• Gaps: 65/666 - (9%)

  Fly   123 IFSMTY----------AYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRP 177
            :|.|.|          .|.:..|||||||:.:.|..:|::....||...:|...::|:.|:|.||
Zfish   102 LFCMCYLTFIQSLMVSGYLSSVITTIEKRYSLRSSESGLLVSCFDIGSLIVVVFISYFGGRGQRP 166

  Fly   178 RWIGFGLLTIVFFCILTTAPHFLYGPGEDALALTSEFGG---MPDENATMEAIEEQRSKTLCRLN 239
            ||:..|.:.|.....|.:.|||: .|......|.|..||   ....:|:..| ..|...||.|
Zfish   167 RWLAVGGVFIAVGAALFSLPHFI-SPPYQLEELNSTVGGEGLCAGASASANA-SGQEKPTLSR-- 227

  Fly   240 GGGAECEVGEGNFAPQLLLFV-AQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLG 303
               .:.|..|...|..:.||: ||.:.|:|.:..||||.:|:|||.||......|::.|.:..||
Zfish   228 ---CQREQEESEHALYVALFICAQILVGMGSTPIYTLGPTYLDDNVKKENASLYLAIMYVMGALG 289

  Fly   304 PAIGYALASFCLRLYIAPQMHPVINNKDPRWLGAWWLGWLV--MGGLLSFSGVFLSMFPKELPRA 366
            ||.||.|....:..|:.|.....|:..|||::|.||.|:|:  :..||....:|  .|||:||
Zfish   290 PAAGYLLGGILIGFYVDPGTVVNIDQGDPRFVGNWWSGFLLCAVAMLLVIFPMF--SFPKKLP-- 350

  Fly   367 VARRKVEENRRREKERLSVKSTEKERLTAELDQKTTAEAKA-----SFQDMLKTFRRLITNKTYM 426
             .|:|  :::|..|:.....|::.|.    :.:|:.|.:.:     :.:|:.|...|:::|.|::
Zfish   351 -PRQK--KSKRGVKKGAGDVSSDDEM----MKEKSQAVSSSMGFGKNIKDLPKAAVRILSNVTFL 408

  Fly   427 CNTLSSIFYLVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISRYKPRA 491
            ..:||........|.:..|.||:||.|:...|:::|:.||.:.:..:.||:.|.|:||.:.|..|
Zfish   409 FVSLSYTAECAIVTAFITFIPKFIESQFGVPASSASIYTGLIIVPSAGVGIFLGGYIIKKLKLGA 473

  Fly   492 RYMAAWNVIVGFLTVAGILAYAFIGCPGNESSVIVNIHDSSLAGNTTT---------CNSACSCD 547
            |..|...:|...:::........:||   ||..:..|:.....|.|.|         ||..|.|.
Zfish   474 REAAKLAMICSGVSLLCFSTLFIVGC---ESINLGGINIPYTTGPTLTLSHRNLTGSCNVNCGCK 535

  Fly   548 YVRYSPVCGENNMTYISACHAGCKKLLVNSEGKKIFYDCSCIPSDDAGNSTSQFKRLTSFDLSND 612
            ...|:||||.:.:||.:.|.|||..:..::.|.:.:.||:|:          |.:::.:....|.
Zfish   536 IHEYAPVCGSDGITYFNPCLAGCSNIANHTSGIRNYSDCACV----------QSRQVITPSGGNH 590

  Fly   613 EVSQNTSVHSQLEALANGQAMPGACPVNCWTQFVAFLAVMCCLKFVGASGRASNFLVSVRCVPEK 677
            |: |...|.:.|.  .||.|:.|.|...|.| .:.||..:..:..:.|..:.|..:|::|.|.|:
Zfish   591 EL-QLVIVKTYLN--ENGFALAGKCERTCGT-LITFLIFLFIVTLITACAQPSVIIVTLRSVDEE 651

  Fly   678 DKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWGKTCTNKGNCWLYDPLSMRYTLNFTAAVF 742
            |:..|:|....|...||:||:||:||.|.|..|::|.:.|...|:||.||..|:|:.....||..
Zfish   652 DRPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQDCGFHGSCWEYDVTSLRFVYFGLAASL 716

  Fly   743 IAIGAIFDLGVWYYAK 758
            ..:|.:|....||..|
Zfish   717 KFLGFLFIFLTWYSLK 732

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	194/637 (30%)
slco5a1a	XP_073776477.1	None