Protein Alignment Oatp58Dc and slco1c1

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_005164528.1
• Gene: slco1c1 / 562772
• ZFINID: ZDB-GENE-041210-50
• Length: 710
• Species: Danio rerio
• Alignment Length: 725
• Identity: 202/725 - (27%)
• Similarity: 317/725 - (43%)
• Gaps: 139/725 - (19%)

  Fly   123 IFSMTYAYFN---------GTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRPR 178
            :.::::|||:         .|||.:|:||.|||...|:|....:|...||.|.::|:..|.|||:
Zfish    50 LVALSFAYFSKALSGSYMKSTITQLERRFDIPSYLIGVIDGSFEIGNLLVIAFVSYFGAKLHRPK 114

  Fly   179 WIGFGLLTIVFFCILTTAPHFLYGPGEDALALTSEFGGMPDENATMEAIEEQRSKTLCRLNGG-- 241
            .|..|.|.:.....|...|||:.|        ..:|     |.:...::....|.:.|.|:..
Zfish   115 IIAIGCLLMSLGTFLIALPHFIIG--------RYKF-----ETSIRLSVNSSSSLSPCSLSSAEP 166

  Fly   242 ------GAECEVGEGNFAPQLLLFVAQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLR 300
                  ...|| .|...:..:.:|:...:.|||.:....||:||:||:..:......:.....:.
Zfish   167 STSSVPSTGCE-HESRLSMWIYVFLGNILRGIGETPVQPLGISYIDDHALEENAAFYIGCVQTIS 230

  Fly   301 MLGPAIGYALASFCLRLYI---APQMHPV-INNKDPRWLGAWWLGWLVMGGLLSFSGVFLSMFPK 361
            ::||..||.|.|.|.::|:   ...|..: |...|.||:||||||:|:.|.:...|.|.....||
Zfish   231 VIGPVFGYLLGSVCAKIYVDIGFVNMESISITPGDARWVGAWWLGYLIAGFITLLSAVPFWFLPK 295

  Fly   362 ELPRAVARRKVEENRRREKERLSVKSTEKERL---TAELDQKTTAEAKASF----QDMLKTFRRL 419
            .||             ..:.|||..|.|:...   :|.|:.|..|:..|:|    :|.|.|.|.|
Zfish   296 SLP-------------LPERRLSKYSPERNSFIKDSALLEHKYQADEPANFLEMAKDFLPTLRSL 347

  Fly   420 ITNKT---YMCNTLSSIFYLVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSG 481
            :.|..   |:|.|:.....|:|...|   .|||||..|.|||:.::.:.|.:.:...|:|:...|
Zfish   348 LGNPVYFLYLCVTIIQFNSLIGMVTY---KPKYIEQHYGQSASKANFLMGVINIPAVALGMFSGG 409

  Fly   482 FIISRYK----PRARYMAAWNVIVGFLTVAGILAYAFIGCP------------GNESSVIVNIHD 530
            .|:.::|    ..|::....:::..||:    |.:..:||.            |.||..:.   |
Zfish   410 VIMKKFKLSIMGAAKFALGTSLLGYFLS----LFFFSMGCENASVAGITMSYNGTESLFMA---D 467

  Fly   531 SSLAGNTTTCNSACSCDYVRYSPVCGENNMTYISACHAGCKKLLVNSEGK---KIFYDCSCIPSD 592
            .||   ..:||:||.|....:.|||||:.:||:|.|.|||:    .|.|.   .:|..||||
Zfish   468 GSL---RASCNAACHCPEKNWDPVCGEDGLTYVSPCLAGCR----TSHGSGMDTVFEQCSCI--- 522

  Fly   593 DAGNSTSQFKRLTSFDLSNDEVSQNTSVHSQLEALANGQAMPGACPVNCWTQFVAFLAVMCCLKF 657
            ..||.|:     |:...:|.|                          :|...|..|||:.....|
Zfish   523 GVGNQTA-----TAGQCNNRE--------------------------SCHRIFPYFLALSVITSF 556

  Fly   658 VGASGRASNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWG-KTCTNKG 721
            :.:.|....:::.:||:..:.|:.|:||.......||.||:||:||.:.|..||.|| |.|..:|
Zfish   557 IISLGGTPGYMLLIRCIKPQLKSLALGFHTLTTRTLAGIPAPIYFGAIIDTTCLKWGHKKCGGRG 621

  Fly   722 NCWLYDPLSMR-----YTLNF-TAAVFIAIGAIFDL--GVWYYAKDLKIFDEDVKEVEMKIVQHE 778
            .|.:|:..:.|     .||.. |.:.|:.|..:..|  .|....:...:........|::.::.|
Zfish   622 ACRIYNTAAYRIAYLGLTLGLRTVSFFLCILGLLVLRRHVQKQERSTMVNGGSAAAGELQALRKE 686

  Fly   779 EEANNEKNTE 788
            |  ||..|:|
Zfish   687 E--NNSCNSE 694

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	187/658 (28%)
slco1c1	XP_005164528.1	MFS_SLCO1C_OATP1C	46..572	CDD:341017	163/599 (27%)