DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Oatp58Dc and LOC556735

DIOPT Version :9

Sequence 1:	NP_001097409.1	Gene:	Oatp58Dc / 37545	FlyBaseID:	FBgn0034716	Length:	789	Species:	Drosophila melanogaster
Sequence 2:	XP_684701.3	Gene:	LOC556735 / 556735	-ID:	-	Length:	859	Species:	Danio rerio

Alignment Length:	691	Identity:	203/691 - (29%)
Similarity:	320/691 - (46%)	Gaps:	103/691 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 IFSMTY----------AYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRP 177
            :|.|.|          .|.:..|||||||:.:.|..:|::....||...||...::|:.|:|.||
Zfish   145 LFCMCYLTFIQSLMVSGYLSSVITTIEKRYSLRSSESGLLVSCFDIGSLLVVVFISYFGGRGQRP 209

  Fly   178 RWIGFGLLTIVFFCILTTAPHFLYGPGEDALALTSEFGGMPDENATMEAIEEQRSKTLCRLNGGG 242
            ||:..|.:.|.....|.:.|||:..|.:           :.:.|::|      .::.|| |||..
Zfish   210 RWLAVGGVFIAVGAALFSLPHFISPPYQ-----------IKEVNSSM------GNEGLC-LNGNR 256

  Fly   243 AECEVG--------EGN-FAPQLLLFV-AQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSY 297
            :...:.        ||| .:..:.||| ||.:.|:|.:..||||.:|:|||.||......|::.|
Zfish   257 SRDALDVSSCPRDQEGNDHSIYVALFVCAQVLVGMGSTPIYTLGPTYLDDNVKKENASLYLAIMY 321

  Fly   298 FLRMLGPAIGYALASFCLRLYIAPQMHPVINNKDPRWLGAWWLGWLVMGGLLSFSGVF----LSM 358
            .:..||||.||.|....:..|:.|:....|...|||::|.||.|:|    |.:|:.:.    :..
Zfish   322 VMGALGPAAGYLLGGVLIGFYVDPKTIVNIEQSDPRFVGNWWSGFL----LCAFAMLLVIFPMFT 382

  Fly   359 FPKELPRAVARRKVEENRRREKERLSVKSTEKERLTAELDQ---KTTAEAKA---SFQDMLKTFR 417
            |||:||   .|.|    ::::|......|.:.:.:..|...   :|.|.:..   ..:|:.|...
Zfish   383 FPKKLP---PRHK----KKKKKHAADSASNDDDDVLKEKSNSKGQTVASSMGFGRDIKDLPKAAI 440

  Fly   418 RLITNKTYMCNTLSSIFYLVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGF 482
            |:::|.|::..:||........|.:..|.||:||.|:...|:.:|:.||.:.:..:.||::|.|:
Zfish   441 RILSNMTFLFVSLSYTAESAIVTAFITFIPKFIESQFGIPASNASIYTGVIIVPSAGVGIVLGGY 505

  Fly   483 IISRYKPRARYMAAWNVIVGFLTVAGILAYAFIGCPGNESSVIVNIHDSSLAGNTTT-------- 539
            ||.:.|..||..|...:|...:::........:||   ||..:..|:.....|.|.|
Zfish   506 IIKKLKLGARESAKLAMICSGVSLLCFSTLFIVGC---ESINLGGINIPYTTGPTLTLTHRNLTG 567

  Fly   540 -CNSACSCDYVRYSPVCGENNMTYISACHAGCKKLLVNSEGKKIFYDCSCI--------PSDDAG 595
             ||..|.|....|:||||.:.:||.:.|.|||..:..:|.|.:.:.||:|:        |:...|
Zfish   568 GCNVNCGCRINEYAPVCGSDGITYFNPCLAGCSTVGNDSTGIRNYTDCACVQSRQVITPPTSGQG 632

  Fly   596 NSTSQFKRLTSFDLSNDEVSQNTSVHSQLEALANGQAMPGACPVNCWTQFVAFLAVMCCLKFVGA 660
            |..                 |...|.:.|.  .||.|:.|.|...|.| .:.||..:..:..:.|
Zfish   633 NQL-----------------QLVIVKTYLN--ENGFALSGKCDRTCNT-LIPFLIFLFIVTLITA 677

  Fly   661 SGRASNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWGKTCTNKGNCWL 725
            ..:.|..:|::|.|.|:::..|:|....|...||:||:||:||.|.|..|::|.:.|...|:||.
Zfish   678 CAQPSAIIVTLRSVDEQERPFALGMQFVLLRTLAYIPTPIYFGAVIDTTCMLWQQDCGIHGSCWE 742

  Fly   726 YDPLSMRYTLNFTAAVFIAIGAIFDLGVWYYAKDLKIFDED 766
            ||..|.|:.....||....:|.||....||..|    :.||
Zfish   743 YDVTSFRFVYFGLAASLKFVGFIFIFLTWYSIK----YKED 779

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_001097409.1	OATP	112..731	CDD:281175	191/654 (29%)
		MFS	114..>518	CDD:119392	122/424 (29%)
		KAZAL_SLC21	537..590	CDD:238650	22/69 (32%)
LOC556735	XP_684701.3	OATP	143..748	CDD:281175	191/654 (29%)
		MFS	146..>545	CDD:119392	125/430 (29%)
		KAZAL_SLC21	565..619	CDD:238650	20/53 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810