Protein Alignment Oatp58Dc and SLCO1C1

DIOPT Version :9

• Sequence 1: NP_001097409.1
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001139418.1
• Gene: SLCO1C1 / 53919
• HGNCID: 13819
• Length: 730
• Species: Homo sapiens
• Alignment Length: 657
• Identity: 179/657 - (27%)
• Similarity: 297/657 - (45%)
• Gaps: 104/657 - (15%)

  Fly   122 CIFSMTY-------AYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRPRW 179
            |..|..|       .|...|||.||:||.|||...|:|....:|...||...::|:..|.|||:.
Human    47 CALSFVYFAKALAEGYLKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKI 111

  Fly   180 IGFGLLTIVFFCILTTAPHFL--------YGPGEDALALTSEFGGMPDENATMEAIEEQRSKTLC 236
            ||.|.:.:....:|...|.|.        |.|..::....|...........:..:|:.:||.
Human   112 IGAGCVIMGVGTLLIAMPQFFMEQYKYERYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKI-- 174

  Fly   237 RLNGGGAECEVGEGNFAPQLLLFVAQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRM 301
                 ..|||| :.:.:..:.:|:...:.|||.:....||::|:||...:......:.....:.:
Human   175 -----SNECEV-DTSSSMWIYVFLGNLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAI 233

  Fly   302 LGPAIGYALASFCLRLYI----APQMHPVINNKDPRWLGAWWLGWLVMGGLLSFSGVFLSMFPKE 362
            :||..|:.|.|.|.:||:    ....|..|..|||:|:||||||:|:.|.:...:.|.....||.
Human   234 IGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPKS 298

  Fly   363 LPRAVARRKVEENRRREKERLSVKSTEKERLTAELDQKTTAEAKASFQDMLKTFRRLITNKT--- 424
            |||:.:|.  :.|...||.:..:    .:....:..|...|:.....:|.|.:.:.|..|..
Human   299 LPRSQSRE--DSNSSSEKSKFII----DDHTDYQTPQGENAKIMEMARDFLPSLKNLFGNPVYFL 357

  Fly   425 YMCNT---LSSIFYLVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISR 486
            |:|.:   .:|:|.:|.|      .|||||.||.||::.::.|.|.:.:...|:|:...|.::.:
Human   358 YLCTSTVQFNSLFGMVTY------KPKYIEQQYGQSSSRANFVIGLINIPAVALGIFSGGIVMKK 416

  Fly   487 YKPR---ARYMAAWNVIVGFLTVAGILAYAFIGCPGNESSVI---------VNIHDSSLAGNTTT 539
            ::..   |..:...:.:.|:|....:.|   :||..::.:.:         |:.|:.:|..:
Human   417 FRISVCGAAKLYLGSSVFGYLLFLSLFA---LGCENSDVAGLTVSYQGTKPVSYHERALFSD--- 475

  Fly   540 CNSACSCDYVRYSPVCGENNMTYISACHAGCKKLLVNSEGKK-IFYDCSC--IPSDDAGNSTSQF 601
            |||.|.|...::.|:||||.:||:|||.|||:  ..|..||. |||:|:|  |.:..:|||:
Human   476 CNSRCKCSETKWEPMCGENGITYVSACLAGCQ--TSNRSGKNIIFYNCTCVGIAASKSGNSS--- 535

  Fly   602 KRLTSFDLSNDEVSQNTSVHSQLEALANGQAMPGACPVN--CWTQFVAFLAVMCCLKFVGASGRA 664
                                          .:.|.|..:  |...|:.||.:.....:..:.|..
Human   536 ------------------------------GIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGI 570

  Fly   665 SNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWG-KTCTNKGNCWLYDP 728
            ..:::.:||:..:.|:.|:|.......:||.||:|::||.:.|..||.|| |.|.::|:|.|||.
Human   571 PGYILLLRCIKPQLKSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDS 635

  Fly   729 LSMRYTL 735
            ...||.:
Human   636 NVFRYQI 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_001097409.1	OATP	112..731	CDD:281175	177/651 (27%)
		MFS	114..>518	CDD:119392	112/423 (26%)
		KAZAL_SLC21	537..590	CDD:238650	26/55 (47%)
SLCO1C1	NP_001139418.1	MFS_SLCO1C_OATP1C	42..579	CDD:341017	153/592 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820