Protein Alignment Oatp58Dc and Oatp74D

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_648989.1
• Gene: Oatp74D / 39954
• FlyBaseID: FBgn0036732
• Length: 819
• Species: Drosophila melanogaster
• Alignment Length: 767
• Identity: 234/767 - (30%)
• Similarity: 362/767 - (47%)
• Gaps: 116/767 - (15%)

  Fly    37 NGKSYDKEKEAGNQDGEETTPKTGKSKKKKQKSEQDRL-MTAEINKLLAESPLEKNVTCGFWIFK 100
            ||.|. .||.|     .|..|.||..|...:.||.:.. ..:::|   ..|..|.:.:||.:..:
  Fly   108 NGHSL-SEKYA-----HEQAPLTGGYKLPPRSSESEESDFDSDLN---GGSSAESSSSCGLFGCR 163

  Fly   101 GTFYQRFANQTAYVLLYGIVGCIFSMTYAYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSA 165
            ..:.:|||:...:::::.:...:..|...||...||||||.|:|.||.|||:...:::.|...:.
  Fly   164 PRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAM 228

  Fly   166 VLAYYAGKGHRPRWIGFGLLTI---VFFCILTTAPHFLYGPGEDAL---ALTSEFGGMPDENA-- 222
            :|.|:||:|||||||..|::..   .|.|.|   |||::  ||..:   .:..:....|..|:
  Fly   229 LLTYFAGRGHRPRWIACGMVLFSIAAFSCAL---PHFIF--GEQLMHSSVILQQTQVSPPNNSFS 288

  Fly   223 --TMEAIEEQRSKTLCRLNG----GGAECEVGEGNFAPQL--------------LLFVAQFISGI 267
              .:.|..||.:..||.|.|    .|:||     |...||              :.|.:...|||
  Fly   289 SHWLNASSEQVNPNLCILGGNQTHSGSEC-----NEERQLEQASHSKITVIVLCIFFGSLLSSGI 348

  Fly   268 GGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAIGYALASFCLRLYIAPQMHPVINNKDP 332
            |.:...|||:.|:|||....::|..::::..:|:||||.|:...|||.|.|: ...:|..:..||
  Fly   349 GQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYV-NFSNPGFDATDP 412

  Fly   333 RWLGAWWLGWLVMGGLLSFSGVFLSMFPKELPRAVARRKVEENRRREKERLSVKSTEKERLTAEL 397
            ||:||||||.:.:|.|:..:.:.:..|||:|     |.|.:...:.......|:..||.:|
  Fly   413 RWIGAWWLGPVAIGSLMLLASIAMFSFPKQL-----RGKQKPPGQTATPAAPVEPEEKPKL---- 468

  Fly   398 DQKTTAEAKASFQDMLKTFRRLITNKTYMCNTLSSIFYLVGYTPYWIFTPKYIEVQYRQSAATSS 462
                        :|..||.||.::|...|..|.|.:|:|:.....:.|.|||:|.|:|.:...::
  Fly   469 ------------KDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDAN 521

  Fly   463 MVTGTVALAFSAVGVLLSGFIISRYKPRARYMAAWNVIVGFLTVAGILAYAFIGCPGNESSVIVN 527
            |:.....:....:|:::||..|.:.||.||.:|||......:..||::...||||..|:.:....
  Fly   522 MIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIGCSMNDFAGYKP 586

  Fly   528 IHDSSLAGNTTTCNSA--CSCDYVRYSPVCGENNMTYISACHAGC-KKLLVNSEGKKIFYDCSCI 589
            ...:|.|....||::|  |:||...::|:|.:..| ||||||||| ...|..|:.:.::.||:||
  Fly   587 SDGNSPALIEPTCSAALNCTCDKENFAPICADGKM-YISACHAGCSSSSLRPSDNRTLYSDCACI 650

  Fly   590 PSDDAGNSTSQFKRLTSFDLSNDEVSQNTSVHSQLEALANGQAMPGACPVNCWTQFVAFLAVMCC 654
            |  ||                                   .:|:.|.|..|| ..|:.|:.:...
  Fly   651 P--DA-----------------------------------PEAVNGYCDNNC-KNFIYFILIFAI 677

  Fly   655 LKFVGASGRASNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWGKTCTN 719
            ..|:.::....:.|:.:||...|||..|||...:...:...:|.||.:|.|.|..||:|...|..
  Fly   678 CVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWKSVCGK 742

  Fly   720 KGNCWLYDPLSMR-YTLNFTAAV-FIAIGAIFDLGVWYYAKDLKIFDEDVKE 769
            .|.|.|||..:.| |.|..||.: |:|.  :.||.||..|..:.|..||.:|
  Fly   743 HGACSLYDADTFRQYFLGITAGIMFLAF--LMDLVVWRKAHRIDIAPEDPQE 792

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	197/648 (30%)
Oatp74D	NP_648989.1	OATP	175..754	CDD:460821	197/649 (30%)