Protein Alignment Oatp58Dc and slco1d1

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001335015.1
• Gene: slco1d1 / 326845
• ZFINID: ZDB-GENE-030131-5044
• Length: 689
• Species: Danio rerio
• Alignment Length: 683
• Identity: 185/683 - (27%)
• Similarity: 296/683 - (43%)
• Gaps: 135/683 - (19%)

  Fly   129 AYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRPRWIGFGLLTIVFFCIL 193
            :|...::|.||:||.:||...|.|....:|....|.|.::|:..|.||||.|..|.|.:.....:
Zfish    33 SYMKSSVTQIERRFDVPSSLIGFIDGSFEIGNLFVIAFVSYFGAKLHRPRLIAAGCLVMSAGSFI 97

  Fly   194 TTAPHFLYGP----------------GEDAL-ALTSEFGGMPDENATMEAIEEQRSKTLCRLNGG 241
            |..|||..|.                .|:.| .||:.......|..|:|:
Zfish    98 TAMPHFFQGQYKYESTISHFSASVNGTENVLPCLTNASLAQDSEIPTVES--------------- 147

  Fly   242 GAECEVGEGNFAPQLLLFVAQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAI 306
            .||||....: :..|.:|:...:.|||.:....||:||:||.:::..|...|:|...:.::||..
Zfish   148 QAECEKASSS-SLWLFVFLGNMLRGIGETPVMPLGLSYLDDFSREENTAFYLALIQTVGIMGPMF 211

  Fly   307 GYALASFCLRLYI---APQMHPV-INNKDPRWLGAWWLGWLVMGGLLSFSGVFLSMFPKELPRAV 367
            |:.|.|||.:||:   ...:..: ||.||.||:||||||:||.||::..:|:.....||.|.|
Zfish   212 GFMLGSFCAKLYVDIGTVDLDSITINYKDSRWVGAWWLGFLVTGGVMLLAGIPFWFLPKSLTR-- 274

  Fly   368 ARRKVEENRRREKERLSVKSTEKERLTAELDQKTTAEAK-------ASFQDMLKTFRRLITNKTY 425
                 :.....||:..:.:..|:||...:.::.....:|       |..:|.|.:.::|.:|..|
Zfish   275 -----QGEPESEKKPGAPEGGEQERFIPDNNKHNPPASKPAPVTMSALAKDFLPSLKKLFSNTIY 334

  Fly   426 MCNTLSSIFYLVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISRYKPR 490
            :....:.:..:.|:.....|.||::|..|.|||:.:..:.|.:.|...|:|::..|||:.|:|..
Zfish   335 VLLVCTGLIQVSGFIGMITFKPKFMEQVYGQSASRAIFLIGIMNLPAVALGIVTGGFIMKRFKVN 399

  Fly   491 ARYMAAWNVIVGFLTVAGILAYAFIGCPGNESSVIVNIHDSSLAGNTTT---------------- 539
            ....|...::...|....:|...|:.|           .:|.:||.|.|
Zfish   400 VLGAAKICIVASVLAFCSMLIQYFLQC-----------DNSQVAGLTVTYQGAPEVSYQTETLIS 453

  Fly   540 -CNSACSCDYVRYSPVCGENNMTYISACHAGCKKLLVNSEG---KKIFYDCSCIPSDDAGNSTSQ 600
             ||..|||....:.|:|..|.:||.|.|.|||:    .|.|   :.:|::||||.
Zfish   454 QCNIGCSCSLKHWDPICASNGVTYTSPCLAGCQ----TSTGIGKEMVFHNCSCIG---------- 504

  Fly   601 FKRLTSFDLSNDEVSQNTSVHSQLEAL---ANGQAMPGACP--VNCWTQFVAFLAVMCCLKFVGA 660
                                    |||   .|..|:.|.||  .:|...|..::||.....|..|
Zfish   505 ------------------------EALLPYTNMSAVLGQCPRKSDCDFMFKIYMAVTVIGAFFSA 545

  Fly   661 SGRASNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWG-KTCTNKGNCW 724
            .|....:::.:|.:..:.|:.|:|....:...|..||.||:||.:.|:.||.|| |.|..:|.|.
Zfish   546 VGATPGYIILLRSITPELKSLALGMHTLIVRTLGGIPPPIYFGALIDKTCLKWGLKQCGGRGACR 610

  Fly   725 LYDP-------LSMRYTLNFTAAVFIAIGAIFD 750
            :||.       |.:.|.|  .::.::..|.:::
Zfish   611 IYDSGAFRNAFLGLIYAL--YSSSYLLFGLLYN 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	182/662 (27%)
slco1d1	NP_001335015.1	MFS	14..558	CDD:475125	159/596 (27%)