Protein Alignment Oatp58Dc and Slco4c1

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_766246.1
• Gene: Slco4c1 / 227394
• MGIID: 2442784
• Length: 722
• Species: Mus musculus
• Alignment Length: 808
• Identity: 216/808 - (26%)
• Similarity: 357/808 - (44%)
• Gaps: 130/808 - (16%)

  Fly     7 PSSLGAELQDLEHGRRESRDESDVESRLL----NNGKSYDKEKEAGNQDGEETTPKTGKSKKKKQ 67
            |||.|..       ||.|...|.||...:    .||.|..:|.|...:..|.:.|.:......:.
Mouse    14 PSSPGTP-------RRASASPSQVEVSAVASRNQNGGSQPRESEEPQKSTEPSPPSSNPPASDEP 71

  Fly    68 KSEQDRLMTAEINKLLAESPLEKNVTCGFWIFKGTFYQRFANQTAYVLLYGIVGCIFSMTYA-YF 131
            ...|    .:|    |.|.|      ||:..|.....||......::|.|    |:.::|.. ..
Mouse    72 PGSQ----LSE----LEEGP------CGWRGFHPQCLQRCNTPQGFLLHY----CLLALTQGIVV 118

  Fly   132 NG----TITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRPRWIGFGLLTIVFFCI 192
            ||    :|:|||||:::.|..||:||...|||..::|..::::..:||:|||:.|....|....:
Mouse   119 NGLVNISISTIEKRYEMKSSLTGLISSSYDISFCVLSLFVSFFGERGHKPRWLAFASFMIGLGAL 183

  Fly   193 LTTAPHFLYGPGEDALALTSEFGGMPDENATMEAIEEQRSKTLCRLNGGGAECEVGEGNFAPQLL 257
            :.:.|||..|        ..|.|.:.::..               |......|.......:....
Mouse   184 VFSLPHFFSG--------RYELGSIFEDTC---------------LTRNSTRCSSSTSLLSNYFY 225

  Fly   258 LFV-AQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAIGYALASFCLRLY--I 319
            :|| .|.:.|.||:..||||.:::||:....|:...:.:.|.:.:|||||||.|....|.:|  |
Mouse   226 VFVLGQLLLGTGGTPLYTLGTAFIDDSVPTHKSSLYIGIGYSMSILGPAIGYVLGGQLLTMYIDI 290

  Fly   320 APQMHPVINNKDPRWLGAWWLGWLVMGGLLSFSGVF-LSMFPKELPRAVARRKVEENRRREKERL 383
            |......:...|||||||||:|:| :..|.::|.:. .|.|||.||   ...|::..
Mouse   291 AMGQSSDLTEDDPRWLGAWWIGFL-LAWLFAWSLIMPFSCFPKHLP---GTAKIQAG-------- 343

  Fly   384 SVKSTEKERLTAELDQKTTAEAKASFQDMLKTFRRLITNKTYMCNTLSSIFYLVGYTPYWIFTPK 448
              |:::..:..:...|.|......|.:|.....:.|:.|..::|..||:....:..|.:..|.||
Mouse   344 --KTSQTHQNNSTSFQHTDENFGKSIKDFPTAVKNLMRNTVFICLVLSTTSEALITTGFATFLPK 406

  Fly   449 YIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISRYKPRARYMAAWNVIVGFLTVAG---IL 510
            :||.|:..:::.::.:.|.|.:..:|:|.:|.|.::|::|.:.:     |.:...|..:|   :|
Mouse   407 FIENQFGLTSSFAATLGGAVLIPGAALGQILGGVLVSKFKMKCK-----NTMKFALCTSGVALVL 466

  Fly   511 AYAFI--GCPGNE--SSVIVNIHDSSLAGN-TTTCNSACSCDYVRYSPVCGENNMTYISACHAGC 570
            ::.||  .|. ||  :.|..:.:.:...|| |..||:.|:|....|.|:||.:.:.|.|.|.|||
Mouse   467 SFVFIYAKCE-NEPFAGVSESYNGTGEMGNLTAPCNANCNCLRSYYYPLCGSDGIQYFSPCFAGC 530

  Fly   571 KKLLVNSEGKKIFYDCSCIPSDDAGNSTSQFKRLTSFDLSNDEVSQNTSVHSQLEALANGQAMPG 635
            ...:.|.: .|::|:||||.           :::||           |:..:..||.|      |
Mouse   531 LNSVSNRK-PKVYYNCSCIE-----------RKITS-----------TAESTDFEAKA------G 566

  Fly   636 ACPVNCWTQFVAFLAV-MCCLKFVGASGRASNFLVSV-RCVPEKDKTAAMGFGMTLCSMLAFIPS 698
            .|...| :....||.: ...:.|...:|  :...||: |||..:.::.|:|....|..:|..||.
Mouse   567 KCRTRC-SNLPIFLGIFFITVIFTFMAG--TPITVSILRCVNHRHRSLALGVQFMLLRLLGTIPG 628

  Fly   699 PIFFGWVFDRVCLVWG-KTCTNKGNCWLYDPLSMRYTLNFTAAVFIAIGAIFD-LGVWYY----- 756
            ||.||.:.|..|::|. ..|..||.||:||.:.|.:.|...:.....|...|: |.:..|
Mouse   629 PIIFGVIIDSTCVLWDVNECGIKGACWIYDNIKMAHMLVAISVTCKVITIFFNGLAIVLYKPPPP 693

  Fly   757 AKDLKIFDEDVKEVEMKIVQHEEEANNE 784
            ..::....::|....:.:.:..::|.||
Mouse   694 GTEVSFQSQNVIVSTISVEEDLDKAENE 721

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	179/637 (28%)
Slco4c1	NP_766246.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		20/81 (25%)
		MFS_SLCO4C_OATP4C	100..602	CDD:341021	156/580 (27%)