Protein Alignment Oatp58Dc and Y70G10A.3

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_499267.1
• Gene: Y70G10A.3 / 190573
• WormBaseID: WBGene00013499
• Length: 690
• Species: Caenorhabditis elegans
• Alignment Length: 693
• Identity: 185/693 - (26%)
• Similarity: 314/693 - (45%)
• Gaps: 111/693 - (16%)

  Fly    80 NKLLAESPLEKNVTCGFWIFKGTFYQRFANQTAYVLLYGIVGCIFSMTY---AYFNGTITTIEKR 141
            :|:..|...|| :.||:.....::.|.|.|....:::.||  |.|..::   |.|...::|:|:|
 Worm    18 HKIEDEDDAEK-LLCGYGACTPSWLQGFHNAKCLLVVLGI--CAFIQSFVVNAIFPVGLSTLERR 79

  Fly   142 FKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRPRWIGFGLLTIVFFCILTTAPHF---LYGP 203
            ||:.|.:|||||...|.:..||...:.::...||:.||||:|.:.:....::...||:   :|.|
 Worm    80 FKMTSTHTGIISSWYDFAVLLVVFPVCHWGNNGHKGRWIGWGGVIMALGSLICALPHWMVDIYHP 144

  Fly   204 GEDALALTSEFGGMPDENATMEAIEEQRSKTLCRLNGGGAECEVGEGN---FAPQLLLFV-AQFI 264
            ..:.|...::||                   .| .|....|| .|:.:   |.|...:|: .|.:
 Worm   145 DVNDLTNQTDFG-------------------QC-ANRDDPEC-AGKPHSSWFNPYFWMFILGQTL 188

  Fly   265 SGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAIGYALASFCLRLYIAPQMHPV--- 326
            .|:|.:..:::|.:|||:|..:..:|..|::...|...||.||.....|.|.||  .....|
 Worm   189 HGVGSTPLFSIGTTYMDENVSQKASPVYLAIHAVLTSFGPVIGVFAGGFLLNLY--DDFDRVERI 251

  Fly   327 -INNKDPRWLGAWWLGWLVMGGLLSFSGVFLSM----FPKELPRAVARRKVEENRRREKERLSVK 386
             :...||||:||||:|:::.    |.|.:.::.    |.:|||.|      :.:|.::..:..|.
 Worm   252 PMERSDPRWVGAWWVGFIIS----SISALMIAFPILAFARELPEA------KRHRAKDVNQCHVA 306

  Fly   387 STEKERLTAELDQKTTAEAKASFQDMLK---TFRRLITNKTYMCNTLSSIFYLVGYTPYWIFTPK 448
            :.:             ..|||. :|::|   ...::::|.|::......||..:....:..|.||
 Worm   307 NGD-------------VNAKAP-RDLMKLPACVWKILSNPTFLVCIFVGIFESIIINGFAAFMPK 357

  Fly   449 YIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISRYKPRARYMAAWNV---IVGFLTVAGIL 510
            .:|.....:...:|.::..|..| :|.||::.|.||.:.|.:...|....:   :...|...|:|
 Worm   358 ILETLLSTNPTLASYLSSVVIFA-AATGVMVGGTIIRQLKLQVGGMLKMIIVCHVFALLFTTGLL 421

  Fly   511 AYA----FIGCP-GNESSVIVNIHDSSLAGNTTTCNSACSCDYVRYSPVCGEN-NMTYISACHAG 569
            ::.    |:|.. |.|...|..:||.|:   ::|||:.|.|. :.::|||..| ...|.||||||
 Worm   422 SHCPQREFVGINLGYEDLSIEKMHDFSI---SSTCNADCHCK-MEWNPVCDRNTGHMYYSACHAG 482

  Fly   570 CKKLLVNSEGKKIFYDCSCIPSDDAGNSTSQFKRLTSFDLSNDEVSQNTSVHSQLEALANGQAMP 634
            |.. ....:|...:..|.|:.|    |||  |..|.      ..:.::..|.:|
 Worm   483 CTG-RTTIDGSSQWSGCGCLTS----NST--FHNLI------HGIKEHPDVLNQ----------- 523

  Fly   635 GACPVNC-WTQFVAFLAVMCCLKFVGASGRASNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPS 698
            |.|..:| :.:::..:.:...:....|||..:. .:.:|.||...:|.|:|...|...:|.|||.
 Worm   524 GYCHQDCGYREYILMVTLFITVVASFASGIPTQ-QIMLRVVPFDQRTLALGVNWTFVRLLGFIPG 587

  Fly   699 PIFFGWVFDRVCLVWGKTCTNKGNCWLYDPLSMRYTLNFTAAV 741
            .|.||.:.|..||.||::|....:|.:|||..:.:|:...|.|
 Worm   588 GILFGIIIDTACLEWGESCGKATSCLVYDPFKLSWTITGLAIV 630

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	173/648 (27%)
Y70G10A.3	NP_499267.1	MFS_SLCO4_OATP4	47..561	CDD:340961	149/592 (25%)