Protein Alignment Oatp58Dc and F21G4.1

DIOPT Version :9

• Sequence 1: NP_001097409.1
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_509659.3
• Gene: F21G4.1 / 181203
• WormBaseID: WBGene00009023
• Length: 640
• Species: Caenorhabditis elegans
• Alignment Length: 709
• Identity: 196/709 - (27%)
• Similarity: 306/709 - (43%)
• Gaps: 129/709 - (18%)

  Fly   113 YVLLYGIVGCIFSMTYAYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRP 177
            :|||..:|..:......|..|.:||:||||...|:.:|.:....||..|:...::.|.....|.|
 Worm    19 FVLLMVLVIAVQGTYLGYVVGMLTTLEKRFGFSSEKSGWLLSLYDIGHTMAILLIGYIGSHYHLP 83

  Fly   178 RWIGFGLLTIVFFCILTTAPHFLYGPGEDALALTSEFGGMPD--ENATMEAIEEQRSKTLCRLNG 240
            |..|.|:       ||::...|:       |||...|.|..|  :...|:..|....:..|..||
 Worm    84 RITGIGV-------ILSSLSMFM-------LALPVLFYGTADYTQEQLMQKKEAYSVEMSCDTNG 134

  Fly   241 ------GGAEC--EVGEGNFAPQLLLFVAQFISGIGGSLYYTLGVSYMDDNTK-KSKTPALLSLS 296
                  .|.:|  |..|...|..:|.| .|..:||..:.:.|:...|:|.|.| |.::|.||.|.
 Worm   135 RREISSQGEDCWREHHEHTNAFIILAF-GQLFAGIFAAPFNTIAYVYIDSNVKQKRESPFLLGLL 198

  Fly   297 YFLRMLGPAIGYALASFCLRLYI----APQMHPVINNKDPRWLGAWWLGWLVMGGLLSFSGVFLS 357
            ..:...|||:|:.|:|....:|.    ||. |  |...|..|:||||||:||.|.......|...
 Worm   199 TSMYAFGPALGFMLSSILNGVYTSLGDAPD-H--IGTHDEHWIGAWWLGFLVCGSAYLILAVPFF 260

  Fly   358 MFPKELPRAVARRKVEENRRRE---KERLSVKSTEKERLTAELDQKTTAEAKASFQDMLKTFRRL 419
            .||:......:...:.|:.|.:   ::||    |.||.:|..|.:         |..:||   :|
 Worm   261 FFPRTYKHPDSFHLMLEHSRPQVSPEDRL----TFKENITLFLRE---------FPMVLK---KL 309

  Fly   420 ITNKTYMCNTLSSIF--YLVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGF 482
            ||||.|:...::.:|  ||:|  .|..:.||:||.||.:||:.:.:.:|.:::...||...|.|:
 Worm   310 ITNKVYITMVIAWMFGSYLIG--GYQTYLPKFIETQYGRSASMADIYSGIISVGAIAVSTALGGW 372

  Fly   483 IISRYK--PRAR---YMAAWNVIVGFLTVAGILAYAF---IGC--PGNESSVIVNI----HDSSL 533
            |:|||.  ||:.   .:.:|.||        :::|..   :||  |..|....|:.    |....
 Worm   373 ILSRYNIAPRSSIICLIGSWIVI--------LVSYIIGMNLGCSQPKVEGLTYVDYASRWHFYHH 429

  Fly   534 AGNTTTCNSACSCDYVRYSPVCGENNMTYISACHAGCKKLLVNSEGKKIFYDCSCIPSDDAGNST 598
            ......|...|:|:.|........|...:.|.|||||.:..:.|   ..:.:|.|.    .||..
 Worm   430 REREQECLEYCNCETVLKFDGVSYNGQNFYSPCHAGCTEYDIYS---NTWSNCQCA----YGNMV 487

  Fly   599 SQFKRLTSFDLSNDEVSQNTSVHSQLEALANGQAMPGACPVNCWTQFVAFLAVMCCLKFVGASGR 663
            .:                             |...|. |.:     |.|:||||....|:|....
 Worm   488 DK-----------------------------GLVHPD-CGI-----FFAYLAVMLIGLFIGNLFF 517

  Fly   664 ASNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWGKTCTN-KGNCWLYD 727
            ....::.:|.|.:::|..|:.....:.::..|||:|:.:|:..|..|::|.:.|.| :|||.|||
 Worm   518 MVTMMIVLRSVFDEEKVIALSLASFITNLFGFIPAPVIYGFFIDLCCILWNRQCPNERGNCVLYD 582

  Fly   728 PLSMRYTLNFTAA-VFIAIGAIFDLGVWYY-AKDLKIFDE----DVKEVEMKIVQHEEE 780
              :..:|..|... .|..:.||...|:.|: :|.:|:.:|    |..|...:..:.|||
 Worm   583 --NDMFTKMFHGVNSFFQVFAIIFAGICYWLSKTVKLPEEMPMVDFPESREREYRDEEE 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_001097409.1	OATP	112..731	CDD:281175	181/652 (28%)
		MFS	114..>518	CDD:119392	130/433 (30%)
		KAZAL_SLC21	537..590	CDD:238650	14/52 (27%)
F21G4.1	NP_509659.3	OATP	18..586	CDD:281175	181/654 (28%)
		MFS	20..>402	CDD:119392	128/425 (30%)
		KAZAL_SLC21	433..481	CDD:238650	13/50 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3626
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28658
OrthoDB	1	1.010	-	-		D1029129at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.830