Protein Alignment Oatp58Dc and F47E1.4

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_509532.1
• Gene: F47E1.4 / 181146
• WormBaseID: WBGene00018568
• Length: 728
• Species: Caenorhabditis elegans
• Alignment Length: 777
• Identity: 182/777 - (23%)
• Similarity: 302/777 - (38%)
• Gaps: 186/777 - (23%)

  Fly   113 YVLLYGIVGCIFSMTYAYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRP 177
            :::|:.:|..:.|:..:|....:.:||::|::.|..:|::....:........:::|:..||:|.
 Worm     7 FIVLFVVVFFLESIGASYIYTALQSIERQFQMSSGISGLLVSATECGYIPCVVIMSYFGSKGNRS 71

  Fly   178 RWIGFGLLTIVFFCILTTAPHFLY----------------------------------------- 201
            ||||.|:|.:....::...|:||:
 Worm    72 RWIGGGVLLMSITYLMLGTPNFLFPTRQQKTNGLNISESLRPTPSQLLPNSTLKDLLSYPLMEDQ 136

  Fly   202 ----------------GPGEDALALTSEFGGMPD------------------------------- 219
                            .|.|......:|.|..|:
 Worm   137 LPSSTYQFLLNLTDDKTPIEQTQTEPTEQGSNPNVTFGIDGYLMKGILIEADNLVKNNYSQNSIK 201

  Fly   220 ----------ENATMEAIEEQRSK-----TLC-------RLNGGGAECEVGEGNFAPQLLLFVAQ 262
                      .|.:::.|::.::|     |:|       |.:...::|..|..|..|.|:.||:.
 Worm   202 QLLSMFIHRRVNRSIDDIQKMKTKAVVPFTVCGKLTNFLRASIENSKCRAGSSNIWPFLVFFVSL 266

  Fly   263 FISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAIGYALASFCLRLYIAPQMHPVI 327
            |..|:|.::.:.||:..:|||.||...|........:|:|||..||.:.||..:.|...|....:
 Worm   267 FFLGVGRTIPWNLGIPLLDDNIKKKHLPMYFGAIASIRVLGPICGYLIGSFSNQFYYTLQAPSGL 331

  Fly   328 NNKDPRWLGAWWLGWLVMGGLLSFSGVFLSMFPKELPRAVARRKVEENRR-REKERLSVKSTEKE 391
            ...:..|:||||||:|::|.|..|..:.|..||:.....:..|::.||:. |..|...:|...||
 Worm   332 TPVNQGWIGAWWLGFLLIGALSMFPSLLLFFFPQGKNSTLQLREIRENKNGRASESKPIKMKIKE 396

  Fly   392 RLTAELDQKTTAEAKASFQDMLKTFRRLITNKTYMCNTLSSIFYLVGYTPYWIFTPKYIEVQYRQ 456
            .:             .|.:.:|.|  ::.|.  .:...:..||...||.   :|.|||:|.|:..
 Worm   397 FV-------------ISCKSVLGT--KIFTG--CLLGRVCDIFAFKGYV---VFLPKYLETQFGI 441

  Fly   457 SAATSSMVTGTVALAFSAVGVLLSGFIISRYKPRARYMAAWNVIVGFLTVAGILAYAFIGCPGNE 521
            .............:....:|:.|.|||..:::...|..|...:||..|.:....:..||||
 Worm   442 PQYLVHRYMSMFGVFGFGLGIALGGFITKKFRLTGRQTALLMMIVSVLNITVYSSKIFIGC---- 502

  Fly   522 SSVIVN---IHDSSLAGN-TTTCNSACSCDYVRYSPVCGENNMTYISACHAGCKKLLVNSEGKKI 582
             ::|||   ::...|..| |..|||.|||:.....|||..:...|.|.|||||::.........|
 Worm   503 -NLIVNSIGLNSRELNYNFTNECNSQCSCENAHLYPVCSADGTAYFSPCHAGCREATQFGSDPVI 566

  Fly   583 -FYDCSCIPSDDAGNSTSQFKRLTSFDLSNDEVSQNTSVHSQLEALANGQAMPGACPVNCWTQFV 646
             |..|.|:.|                                      |......|...|....:
 Worm   567 GFASCECVES--------------------------------------GVVSKSFCQNKCQFSSI 593

  Fly   647 AFLAVMCCLKFVGASGRASNFLVSVRCVPEKDKTAAMGF-GMTLCSMLAFIPSPIFFGWVFDRVC 710
            .|||.:....||.......:.|:.:|.|....::.:||. ||.: |:...:||.|.:|.|.|..|
 Worm   594 LFLATVLLGSFVAGVAVVPDMLILLRSVDVGSRSLSMGLQGMAI-SLFGTLPSSIIWGLVIDTAC 657

  Fly   711 LVWGKTCTN-KGNCWLYDPLSMRYTLN--FTAAVFIAIGAIFDLGVWYYAKDLKIFDEDVKE 769
            .||.|||.. .|:|.:||...:|..::  :....||::  :.|:.||..|.:|||.|:.|.:
 Worm   658 RVWDKTCNGANGSCSIYDSDHLRIWMHLLYVGVRFISL--LSDIYVWKNAGNLKIMDDPVAD 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	170/735 (23%)
F47E1.4	NP_509532.1	oat	95..707	CDD:273279	155/677 (23%)