Protein Alignment Oatp58Dc and Oatp26F

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: XP_061514349.1
• Gene: Oatp26F / 1275562
• VectorBaseID: AGAMI1_012141
• Length: 783
• Species: Anopheles gambiae
• Alignment Length: 840
• Identity: 197/840 - (23%)
• Similarity: 329/840 - (39%)
• Gaps: 180/840 - (21%)

  Fly    42 DKEKEAGNQ--DGEETTPKTGKSKKKKQKSEQDRLMTAEINKLLAE------------------- 85
            |..|.:.|.  :...|||.||.:..:.:.::......|..:.:..|
Mosquito     9 DSVKMSSNNAPNSAATTPSTGGTTVQTESTKCGGSYGAPSSPIALEEGGCPPIKVAAGDEEPALQ 73

  Fly    86 ---SPLEKNVTCGFWIFKGTFYQRFANQTAYVLLYGIVGCIFSMTY-AYFNGTITTIEKRFKIPS 146
               :|..:...||::..:..:.:||......:......|.:..:.. .:.|..|||||:||.:.|
Mosquito    74 RPATPPPRAYHCGWFALRPKWMERFMTPKWALFWLCWAGAVQGLVVNGFINVVITTIERRFGLRS 138

  Fly   147 KNTGIISVGNDISQTLVSAVLAYYAGK--GHRPRWIGFGLLTIVFFCILTTAPHFLYG----PGE 205
            ..||:::.|.||:..|....::|:.|:  ..:|||||:|:..:.....:...||||.|    ...
Mosquito   139 TQTGLVASGYDIASFLCLVPVSYFGGRLGASKPRWIGWGVAVMGLGAFVFALPHFLVGQYRATNS 203

  Fly   206 D------ALALTSEFGGMPDENATMEAIEEQ---RSKTLCRL-NGGGAECEVGEGNFAPQLLLFV 260
            |      |.||.:...|     |::||:.|.   ...|:..| |||.......|.........|.
Mosquito   204 DQNVCTLATALVTNGTG-----ASVEALTELVGCNHDTVSPLANGGQGPTSDSENLSWNVWFFFT 263

  Fly   261 AQFISGIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAIGYALASFCLRLY------- 318
            ||.:.|.|.|..|||||:|:|:|..|..:...|.:.|.:.::|||.||.:....|..|
Mosquito   264 AQLLLGAGASPLYTLGVTYIDENVSKKMSSVYLGIYYTMAVVGPAAGYVIGGQLLLFYTDMFVVD 328

  Fly   319 -----IAPQMHPVINNKDPRWLGAWWLGWLVMGGLLSFSGVFLSMFPKELPRAVARRKVEENRRR 378
                 :.|  |..:      |:||||:|::.|........|.:..:|..||.:...:||.|..|.
Mosquito   329 ATTLGLTP--HSKV------WVGAWWIGFVFMAAFCLLLAVPILAYPPALPGSEKLQKVSEAHRG 385

  Fly   379 EKERLSVKSTEKERLTAELDQKTTAEAKASFQDMLKTFRRLITNKTYMCNTLSSIFYLVGYTPYW 443
            ..:.               |.:.:.|.....:.:.:....|:.|.|:....|:.....:..:.:.
Mosquito   386 GDDG---------------DGERSQETFTKIKQIPRALLALLRNPTFFFLNLAGASEGLVISGFA 435

  Fly   444 IFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISRYKPRARYMAAWNVIVGFLTVAG 508
            :|.||.||.|:..:|..|:::.|.:.:.....|..|.|:::.:..      .:.:.|:.|...|.
Mosquito   436 VFLPKLIENQFSVTAVWSALLMGIITVPAGGGGTFLGGYLVKKLH------LSCSGIIKFCLFAT 494

  Fly   509 ILAYA-----FIGCPGNESSVIV-------NIHDSSLAGNT-------------TTCNSACSCDY 548
            |.|..     |:.||....:.:.       |: |:..|.:|             ..||..|:|..
Mosquito   495 IFAALFTVCFFLSCPNLTFAGVTAPYFPHENL-DTPYARSTEPRDLYYLPKNLDNACNDRCACSR 558

  Fly   549 VRYSPVCGENNMTYISACHAGCKKLLVNSEGKKIFYDCSCIPSDDAGNSTSQFKRLTSFDLSNDE 613
            ..|.|:||.:.:.|.|.|||||.: .:|.|..|::.||:||
Mosquito   559 RNYEPICGADGIMYYSPCHAGCSE-EINLENAKVYRDCTCI------------------------ 598

  Fly   614 VSQNTSVHSQLEALANG---QAMPGACPVNC---W--------TQFVAFLAVMCCLKFVGASGRA 664
               |.:.|.:..||..|   .|:...|...|   |        ..|..|||.|..|.
Mosquito   599 ---NATFHGEQSALYGGGSYDAVNTMCQSQCDHLWIFVMLCFLVMFFTFLATMPALS-------- 652

  Fly   665 SNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWGK-TCTNKGNCWLYDP 728
                .::|||.:..::.|:|.......:|..||:|:.||.:.|..|::|.: :|.:.|.|.:||.
Mosquito   653 ----ATLRCVHDDQRSFALGIQWIKVRVLGTIPAPMIFGRLIDETCILWQESSCDDHGACLVYDN 713

  Fly   729 LSMRYTLNFTAAVFIAIGAIFDLGVWYYAKDLKIFDEDVKEVEMKIVQHEEEANNEKNTE 788
            ..|...:...|.:..|...:|..|.|:|            .:..|.:.:.:.|.::|.|:
Mosquito   714 AFMSKYMLLLALIGKACSILFFFGAWFY------------YIPPKTITNGDTATHQKQTD 761

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	171/686 (25%)
Oatp26F	XP_061514349.1	None