Protein Alignment Oatp58Dc and Slco3a1

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_076397.2
• Gene: Slco3a1 / 108116
• MGIID: 1351867
• Length: 710
• Species: Mus musculus
• Alignment Length: 763
• Identity: 195/763 - (25%)
• Similarity: 321/763 - (42%)
• Gaps: 146/763 - (19%)

  Fly    48 GNQDGEETTPKTGKSKKKKQKSEQDRLMTAEINKLLAESPLEKNVTC--GFWIFKGTFYQRFANQ 110
            |.:.||....:..::||||:|                       |:|  ...||       ..::
Mouse    12 GGRSGELQGDEAQRNKKKKKK-----------------------VSCFSNIKIF-------LVSE 46

  Fly   111 TAYVLLYGIVGCIFSMTYAYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGH 175
            .|.:|..|.||       ||....:||:|:||.:.|.:.|:|:...:|....:...::|:..:||
Mouse    47 CALMLAQGTVG-------AYLVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGH 104

  Fly   176 RPRWIGFGLLTIVFFCILTTAPHFL-----YGPGEDALALTSEFGGMPDENATMEAIEEQRSKTL 235
            |||.||.|.:.:....:|:..|.||     |..||      ..:|.              ..:.:
Mouse   105 RPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGE------IRWGA--------------EGRDV 149

  Fly   236 CRLNGGGAE--------CEVGEGNFAPQLLLFVAQFISGIGGSLYYTLGVSYMDDNTKKSKTPAL 292
            |..||..::        |..........|||..||.:.|||.:....|||||:||:.::..:...
Mouse   150 CATNGSSSDEGPDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLY 214

  Fly   293 LSLSYFLRMLGPAIGYALASFCLRLYI----APQMHPVINNKDPRWLGAWWLGWLVMGGLLSFSG 353
            :.:.:.:.:.|||.|:.|.|||.::|:    ....:..|...||||:||||.|:|:.|.||.||.
Mouse   215 IGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSS 279

  Fly   354 VFLSMFPKELPRAVARRKVEENRRREKERLSVKSTEKER-------LTAELDQKTTAEAKASFQD 411
            :.:..||:.||       ...:...|.|:..:...|.||       |...|:..::|......:.
Mouse   280 LLMFGFPQSLP-------PHSDPGMESEQAMLPEREYERPKPSNGVLRHPLEPDSSASCFQQLRV 337

  Fly   412 MLKTFRRLITNKTYMCNTLSSIFYLVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVG 476
            :.|..:.|::|..:.|..|::...:.....:..|..||:|.|:..:.::::.:.|..|:..:.:|
Mouse   338 IPKVTKHLLSNPVFTCIVLAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLG 402

  Fly   477 VLLSGFIISRYKPRARYMAAWNVIVGFLTVAGILAYAFIGC-PGNESSVIVNIHDSSLAGNT--- 537
            :.|.|.::.:....|.......::|..::.|..:::.|:|| .|..:.|.|...::|..|:.
Mouse   403 IFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVRYGNNSARGSALDP 467

  Fly   538 -TTCNSACSCDYVRYSPVCGENNMTYISACHAGCKKLLVNSEGKKIFYDCSCIPSDDAGNSTSQF 601
             :.||:.|.|....::||||.:.:||:|||.|||..  .|..|      |:|:
Mouse   468 YSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNS--TNLTG------CACL------------ 512

  Fly   602 KRLTSFDLSNDEVSQNTSVHSQLEALANGQAMPGACP-VNCWTQFVAFLAVMCCLKFVGASGRAS 665
                            |:|..:     |...:||.|| ..|...|:.||.|||....:||..:..
Mouse   513 ----------------TTVPPE-----NASVVPGKCPSPGCQEAFLTFLCVMCVCSLIGAMAQTP 556

  Fly   666 NFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWGKTCTNKGNCWLYDPLS 730
            :.::.:|.|..:.|:.|:|....|..:|.|||.|:.||...|..||.|...|..:|.|.|||.:.
Mouse   557 SVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACVLYDNVV 621

  Fly   731 MRYTLNFTAAVFIAIGAIFDLGVWYYAKDLKIFDEDVKEVEMKIVQHE 778
            .||.....|....:...|.....|...:         |..:..|..||
Mouse   622 YRYLYVSIAIALKSFAFILYTTTWQCLR---------KNYKRYIKNHE 660

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	173/647 (27%)
Slco3a1	NP_076397.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		3/12 (25%)
		MFS_SLCO3_OATP3	39..563	CDD:340960	153/605 (25%)