Protein Alignment Oatp58Dc and slco2a1

DIOPT Version :10

• Sequence 1: NP_611659.2
• Gene: Oatp58Dc / 37545
• FlyBaseID: FBgn0034716
• Length: 789
• Species: Drosophila melanogaster
• Sequence 2: NP_001428961.1
• Gene: slco2a1 / 100038802
• ZFINID: ZDB-GENE-060606-3
• Length: 625
• Species: Danio rerio
• Alignment Length: 673
• Identity: 186/673 - (27%)
• Similarity: 301/673 - (44%)
• Gaps: 119/673 - (17%)

  Fly   107 FANQTAYVLLYGIVGCIFSMTYAYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYA 171
            |.|...:||.:|::.....:..:||..||||||:|:.:.|.::|.||..:::..|::.|.::|..
Zfish    16 FCNIKIFVLCHGLLQLTQLLYSSYFKSTITTIERRYGLDSLSSGTISSLHEVGNTVLIAFVSYLG 80

  Fly   172 GKGHRPRWIGFGLLTIVFFCILTTAPHFLYGPGEDALALTSEFGGMPDENATMEAIEEQRSKTLC 236
            .:.||||:||.|.|.:....::...||||..|                  .|.:::.....:.:|
Zfish    81 SRVHRPRFIGLGGLLMSISAMILALPHFLSQP------------------YTYDSVLHASRQDMC 127

  Fly   237 --RLNGGGAECEVGEGNFAPQL-------LLFVAQFISGIGGSLYYTLGVSYMDDNTKKSKTPAL 292
              |.|..|||. .|:.:....:       |:..||.:.|||.......|:||:||......:|..
Zfish   128 YLRANVTGAEA-CGQEDSRKLMDTSKFWVLMATAQLLFGIGSVPIQPFGISYIDDFAGAGNSPLY 191

  Fly   293 LSLSYFLRMLGPAIGYALASFCLRLYI---------APQMHPVINNKDPRWLGAWWLGWLVMGGL 348
            :::.:.:.:.||:.||.|.|..||:|:         |.::.||    ||||:||||:|.|:..|.
Zfish   192 IAILFAVSVFGPSFGYLLGSVVLRIYVDVDKSSAGEALELTPV----DPRWVGAWWIGLLITSGG 252

  Fly   349 LSFSGVFLSMFPKELPRAVARRKVEENRRREKERLSVKSTEKERLTAELDQKTTAEAKASFQDML 413
            |:.:.:....||:.|       .||::...|.|.:      ||      |.|.:..:...|..|.
Zfish   253 LALTSIPYFFFPRSL-------HVEQSFNLEGEIM------KE------DPKKSESSLLDFFKMF 298

  Fly   414 -KTFRRLITNKTYMCNTLSSIFYLVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGV 477
             |.|.||:.:..:|...|....:.........|..|::|.||..|||.||::.|.:.|...|:|:
Zfish   299 PKIFVRLLLSPLFMLLVLCQCCFSSVIAGLATFLNKFLERQYSASAAYSSLLIGALNLPSIAIGM 363

  Fly   478 LLSGFIISRYKPRARYMAAWNVIVGFLTVAGILAYAFIGCPGNESSVIVNIHDSSLAGNTTTCNS 542
            :|.|.|:.|:....|.:..::|::..::|...:...|:|||..:.:.:..|..:|..|...||::
Zfish   364 VLGGLIMKRWGLSFRAIPRFSVVMLTISVFCCVPLFFMGCPTQDVAGVYPIKSNSTNGIHLTCSA 428

  Fly   543 ACSCDYVRYSPVCGE-NNMTYISACHAGCKKLLVNSEGK---KIFYDCSCIPSDDAGNSTSQFKR 603
            .|||....::||||| ||:.|||.|||||.....:.:..   :.:.:|.|||:
Zfish   429 NCSCPISTFNPVCGEGNNIEYISPCHAGCANYTTDPKNPYRVQSYINCKCIPT------------ 481

  Fly   604 LTSFDLSNDEVSQNTSVHSQLEALANGQAMPGACPVNCWTQFVAFLAVMCCLKFVGASGRASN-- 666
                                      |.|.||.|...| ..::  |.||..:...|.....::
Zfish   482 --------------------------GTAKPGPCSNTC-PHYL--LPVMLLISLAGLIASLTHNP 517

  Fly   667 -FLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWGKTCTNKGNCWLYDP-- 728
             :::.:|.||.::|:.|:|....|..:|.::|:|..||...|..|:.|...|..|..|..||.
Zfish   518 IYMMVLRAVPPEEKSFAIGIQFLLLRVLTWLPAPALFGMTIDSTCIWWKTACEKKQGCGYYDNNL 582

  Fly   729 LSMRY--------TLNFTAAVFI 743
            |..||        ||......||
Zfish   583 LRNRYLGLQVGYKTLGIALLAFI 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Oatp58Dc	NP_611659.2	OATP	113..731	CDD:460821	178/645 (28%)
slco2a1	NP_001428961.1	None